Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136135645> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3136135645 endingPage "23" @default.
- W3136135645 startingPage "23" @default.
- W3136135645 abstract "T-helper 17 plays a novel role in inflammation in gastritis by producing IL-17A, IL-17A gene polymorphisms that might be responsible for disease susceptibility and development of different gastric lesions.The aims of study was to determine the association of IL-17A (G197A) genotype and allele frequency with disease phenotype and risk with different gastric lesions.Case controlled study involved 30 gastroduodenal ulcer, 30 chronic gastritis and 30 subjects as a control group with negative endoscopic findings. After genomic DNA extraction, IL-17A (G197A)ARMS-PCR genotyping were done for all cases. Serum IL-17A was measured using ELISA method and tissue expression was visualized using immunohistochemistry staining method.The results showed that allele A was significantly frequent in gastroduodenal ulcer more than that in healthy control odd ratio= 4 (1.42-10.46), and none significantly with chronic gastritis p=0.071. Serum IL-17A was significantly higher in gastroduodenal ulcer (116.45±48.09 pg/ml), chronic gastritis (78.02±30.17pg/ml) and healthy control 19.36±9.28 pg/ml).However, the serum IL-17A level is not related to the allele pattern of each group. The tissue expression was expressed as dense granular cytoplasmic and membranous of inflammatory cells. Interestingly, the percentage of IL-17A protein expression was significantly higher in gastroduodenal ulcer (38.2±16.55%), chronic gastritis (30.89±14.02%) and normal mucosa (2.8±3.02%). Furthermore, patients with strong intensity of IL-17A stained mucosa were frequently carrier for mutant allele (68%).IL-17A might predispose for aggressive inflammation of advanced lesions in stomach like ulcer." @default.
- W3136135645 created "2021-03-29" @default.
- W3136135645 creator A5027479547 @default.
- W3136135645 creator A5028004681 @default.
- W3136135645 creator A5062460751 @default.
- W3136135645 date "2021-01-01" @default.
- W3136135645 modified "2023-10-16" @default.
- W3136135645 title "Interleukin- 17agene Polymorphism, Serum Level and Its Tissue Expression in Iraqi Patients Gastric Lesions" @default.
- W3136135645 cites W2004186675 @default.
- W3136135645 cites W2025940700 @default.
- W3136135645 cites W2055271346 @default.
- W3136135645 cites W2092289533 @default.
- W3136135645 cites W2092304883 @default.
- W3136135645 cites W2113860198 @default.
- W3136135645 cites W2114518240 @default.
- W3136135645 cites W2134728320 @default.
- W3136135645 cites W2143100947 @default.
- W3136135645 cites W2149549727 @default.
- W3136135645 cites W2162450874 @default.
- W3136135645 cites W2162859744 @default.
- W3136135645 cites W2163927668 @default.
- W3136135645 cites W2464998802 @default.
- W3136135645 cites W2529822899 @default.
- W3136135645 cites W2584985211 @default.
- W3136135645 cites W2774344582 @default.
- W3136135645 cites W2782400666 @default.
- W3136135645 cites W2947282733 @default.
- W3136135645 cites W3091883823 @default.
- W3136135645 doi "https://doi.org/10.5455/medarh.2021.75.23-26" @default.
- W3136135645 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8116103" @default.
- W3136135645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34012194" @default.
- W3136135645 hasPublicationYear "2021" @default.
- W3136135645 type Work @default.
- W3136135645 sameAs 3136135645 @default.
- W3136135645 citedByCount "0" @default.
- W3136135645 crossrefType "journal-article" @default.
- W3136135645 hasAuthorship W3136135645A5027479547 @default.
- W3136135645 hasAuthorship W3136135645A5028004681 @default.
- W3136135645 hasAuthorship W3136135645A5062460751 @default.
- W3136135645 hasBestOaLocation W31361356452 @default.
- W3136135645 hasConcept C104317684 @default.
- W3136135645 hasConcept C126322002 @default.
- W3136135645 hasConcept C135763542 @default.
- W3136135645 hasConcept C142724271 @default.
- W3136135645 hasConcept C180754005 @default.
- W3136135645 hasConcept C204232928 @default.
- W3136135645 hasConcept C2776409635 @default.
- W3136135645 hasConcept C2776914184 @default.
- W3136135645 hasConcept C2778677798 @default.
- W3136135645 hasConcept C2779422922 @default.
- W3136135645 hasConcept C2780561475 @default.
- W3136135645 hasConcept C2781443798 @default.
- W3136135645 hasConcept C31467283 @default.
- W3136135645 hasConcept C47348012 @default.
- W3136135645 hasConcept C55493867 @default.
- W3136135645 hasConcept C71924100 @default.
- W3136135645 hasConcept C86803240 @default.
- W3136135645 hasConcept C90924648 @default.
- W3136135645 hasConceptScore W3136135645C104317684 @default.
- W3136135645 hasConceptScore W3136135645C126322002 @default.
- W3136135645 hasConceptScore W3136135645C135763542 @default.
- W3136135645 hasConceptScore W3136135645C142724271 @default.
- W3136135645 hasConceptScore W3136135645C180754005 @default.
- W3136135645 hasConceptScore W3136135645C204232928 @default.
- W3136135645 hasConceptScore W3136135645C2776409635 @default.
- W3136135645 hasConceptScore W3136135645C2776914184 @default.
- W3136135645 hasConceptScore W3136135645C2778677798 @default.
- W3136135645 hasConceptScore W3136135645C2779422922 @default.
- W3136135645 hasConceptScore W3136135645C2780561475 @default.
- W3136135645 hasConceptScore W3136135645C2781443798 @default.
- W3136135645 hasConceptScore W3136135645C31467283 @default.
- W3136135645 hasConceptScore W3136135645C47348012 @default.
- W3136135645 hasConceptScore W3136135645C55493867 @default.
- W3136135645 hasConceptScore W3136135645C71924100 @default.
- W3136135645 hasConceptScore W3136135645C86803240 @default.
- W3136135645 hasConceptScore W3136135645C90924648 @default.
- W3136135645 hasIssue "1" @default.
- W3136135645 hasLocation W31361356451 @default.
- W3136135645 hasLocation W31361356452 @default.
- W3136135645 hasLocation W31361356453 @default.
- W3136135645 hasOpenAccess W3136135645 @default.
- W3136135645 hasPrimaryLocation W31361356451 @default.
- W3136135645 hasRelatedWork W1991714105 @default.
- W3136135645 hasRelatedWork W2041339719 @default.
- W3136135645 hasRelatedWork W2241145060 @default.
- W3136135645 hasRelatedWork W2393990627 @default.
- W3136135645 hasRelatedWork W2396120344 @default.
- W3136135645 hasRelatedWork W2416219706 @default.
- W3136135645 hasRelatedWork W2466041147 @default.
- W3136135645 hasRelatedWork W2912166899 @default.
- W3136135645 hasRelatedWork W1776694564 @default.
- W3136135645 hasRelatedWork W2463872201 @default.
- W3136135645 hasVolume "75" @default.
- W3136135645 isParatext "false" @default.
- W3136135645 isRetracted "false" @default.
- W3136135645 magId "3136135645" @default.
- W3136135645 workType "article" @default.