Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136137750> ?p ?o ?g. }
- W3136137750 endingPage "5300" @default.
- W3136137750 startingPage "5291" @default.
- W3136137750 abstract "An innovative biosensing assay was developed for simplified, cost-effective, and sensitive detection. By rapid, direct treatment of target proteins with iron porphyrin (TPPFe) in situ, a carboxyl group of amino acid conjugates with an Fe atom of the TPPFe molecule, forming a stable protein complex. We have shown that this complex not only maintains the integrity and functions of original proteins but also acquires peroxidase activity that can turn TMB to a comparably visible signal like that in ELISA. This study is unique since such conversion is difficult to achieve with standard chemical modification or molecular biology methods. In addition, the proposed immunoassay is superior to traditional ELISA as it eliminates an expensive and complicated cross-linking process of an enzyme-labeled antibody. From a practical point of view, we extended this assay to rapid detection of clinically relevant proteins and glucose in blood samples. The results show that this simple immunoassay provides clinical diagnosis, food safety, and environmental monitoring in an easy-to-implement manner." @default.
- W3136137750 created "2021-03-29" @default.
- W3136137750 creator A5000678915 @default.
- W3136137750 creator A5006554681 @default.
- W3136137750 creator A5016462503 @default.
- W3136137750 creator A5025982296 @default.
- W3136137750 creator A5039995219 @default.
- W3136137750 creator A5046735380 @default.
- W3136137750 creator A5068484115 @default.
- W3136137750 creator A5074586582 @default.
- W3136137750 creator A5087102112 @default.
- W3136137750 date "2021-03-18" @default.
- W3136137750 modified "2023-10-18" @default.
- W3136137750 title "De Novo Development of a Universal Biosensing Platform by Rapid Direct Native Protein Modification" @default.
- W3136137750 cites W1717177505 @default.
- W3136137750 cites W2006385105 @default.
- W3136137750 cites W2026353155 @default.
- W3136137750 cites W2028364955 @default.
- W3136137750 cites W2028514569 @default.
- W3136137750 cites W2049188949 @default.
- W3136137750 cites W2049991844 @default.
- W3136137750 cites W2052507172 @default.
- W3136137750 cites W2053329137 @default.
- W3136137750 cites W2054682788 @default.
- W3136137750 cites W2055605961 @default.
- W3136137750 cites W2081938042 @default.
- W3136137750 cites W2234759986 @default.
- W3136137750 cites W2249321396 @default.
- W3136137750 cites W2254963963 @default.
- W3136137750 cites W2261430354 @default.
- W3136137750 cites W2274967631 @default.
- W3136137750 cites W2293587153 @default.
- W3136137750 cites W2299493855 @default.
- W3136137750 cites W2460414839 @default.
- W3136137750 cites W2464585615 @default.
- W3136137750 cites W2468124188 @default.
- W3136137750 cites W2485032695 @default.
- W3136137750 cites W2522577652 @default.
- W3136137750 cites W2527322609 @default.
- W3136137750 cites W2549471832 @default.
- W3136137750 cites W2557128058 @default.
- W3136137750 cites W2564904876 @default.
- W3136137750 cites W2571286449 @default.
- W3136137750 cites W2579700567 @default.
- W3136137750 cites W2588285222 @default.
- W3136137750 cites W2591310089 @default.
- W3136137750 cites W2592375018 @default.
- W3136137750 cites W2603262868 @default.
- W3136137750 cites W2670390373 @default.
- W3136137750 cites W2751140261 @default.
- W3136137750 cites W2765723941 @default.
- W3136137750 cites W2770832678 @default.
- W3136137750 cites W2778741038 @default.
- W3136137750 cites W2784004756 @default.
- W3136137750 cites W2790553494 @default.
- W3136137750 cites W2794443911 @default.
- W3136137750 cites W2799529459 @default.
- W3136137750 cites W2803928887 @default.
- W3136137750 cites W2886783312 @default.
- W3136137750 cites W2891032897 @default.
- W3136137750 cites W2895287270 @default.
- W3136137750 cites W2912829358 @default.
- W3136137750 cites W2914650232 @default.
- W3136137750 cites W2922090852 @default.
- W3136137750 cites W2931006058 @default.
- W3136137750 cites W2937099783 @default.
- W3136137750 cites W2938787043 @default.
- W3136137750 cites W2962660071 @default.
- W3136137750 cites W2982531510 @default.
- W3136137750 cites W2986289837 @default.
- W3136137750 cites W2990846908 @default.
- W3136137750 cites W3008228982 @default.
- W3136137750 cites W3026028284 @default.
- W3136137750 cites W3030698288 @default.
- W3136137750 doi "https://doi.org/10.1021/acs.analchem.1c00341" @default.
- W3136137750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33734672" @default.
- W3136137750 hasPublicationYear "2021" @default.
- W3136137750 type Work @default.
- W3136137750 sameAs 3136137750 @default.
- W3136137750 citedByCount "3" @default.
- W3136137750 countsByYear W31361377502022 @default.
- W3136137750 countsByYear W31361377502023 @default.
- W3136137750 crossrefType "journal-article" @default.
- W3136137750 hasAuthorship W3136137750A5000678915 @default.
- W3136137750 hasAuthorship W3136137750A5006554681 @default.
- W3136137750 hasAuthorship W3136137750A5016462503 @default.
- W3136137750 hasAuthorship W3136137750A5025982296 @default.
- W3136137750 hasAuthorship W3136137750A5039995219 @default.
- W3136137750 hasAuthorship W3136137750A5046735380 @default.
- W3136137750 hasAuthorship W3136137750A5068484115 @default.
- W3136137750 hasAuthorship W3136137750A5074586582 @default.
- W3136137750 hasAuthorship W3136137750A5087102112 @default.
- W3136137750 hasConcept C104317684 @default.
- W3136137750 hasConcept C134306372 @default.
- W3136137750 hasConcept C159654299 @default.
- W3136137750 hasConcept C160756335 @default.
- W3136137750 hasConcept C162008176 @default.
- W3136137750 hasConcept C171250308 @default.