Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136139429> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3136139429 abstract "Abstract Brain tumors are characterised by infiltration along the white matter tracts, posing significant challenges to precise treatment. Mounting evidence shows that an infiltrative tumor can interfere with the brain network diffusely. Therefore, quantifying structural connectivity has potential to identify tumor invasion and stratify patients more accurately. The tract-based statistics (TBSS) is widely used to measure the white matter integrity. This voxel-wise method, however, cannot directly quantify the connectivity of brain regions. Tractography is a fiber tracking approach, which has been widely used to quantify brain connectivity. However, the performance of tractography on the brain with tumors is biased by the tumor mass effect. A robust method of quantifying the structural connectivity in brain tumor patients is still lacking. Here we propose a method which could provide robust estimation of tract strength for brain tumor patients. Specifically, we firstly construct an unbiased tract template in healthy subjects using tractography. The voxel projection procedure of TBSS is employed to quantify the tract connectivity in patients, based on the location of each tract fiber from the template. To further improve the standard TBSS, we propose an approach of iterative projection of tract voxels, under the guidance of tract orientation measured by voxel-wise eigenvectors. Compared to the conventional tractography methods, our approach is more sensitive in reflecting functional relevance. Further, the different extent of network disruption revealed by our approach correspond to the clinical prior knowledge of tumor histology. The proposed method could provide a robust estimation of the structural connectivity for brain tumor patients." @default.
- W3136139429 created "2021-03-29" @default.
- W3136139429 creator A5069648079 @default.
- W3136139429 creator A5079386554 @default.
- W3136139429 creator A5087866299 @default.
- W3136139429 date "2021-03-24" @default.
- W3136139429 modified "2023-09-23" @default.
- W3136139429 title "Quantifying structural connectivity in brain tumor patients" @default.
- W3136139429 cites W1591163814 @default.
- W3136139429 cites W1967424170 @default.
- W3136139429 cites W1978415409 @default.
- W3136139429 cites W2000133863 @default.
- W3136139429 cites W2019042031 @default.
- W3136139429 cites W2058046532 @default.
- W3136139429 cites W2060464767 @default.
- W3136139429 cites W2126838454 @default.
- W3136139429 cites W2145132952 @default.
- W3136139429 cites W2150667092 @default.
- W3136139429 cites W2504084072 @default.
- W3136139429 cites W2677983544 @default.
- W3136139429 cites W2766098209 @default.
- W3136139429 cites W2890740202 @default.
- W3136139429 cites W2905468184 @default.
- W3136139429 cites W2945276566 @default.
- W3136139429 cites W2970898057 @default.
- W3136139429 cites W2995125302 @default.
- W3136139429 cites W3009019117 @default.
- W3136139429 cites W3135033332 @default.
- W3136139429 doi "https://doi.org/10.1101/2021.03.19.21253837" @default.
- W3136139429 hasPublicationYear "2021" @default.
- W3136139429 type Work @default.
- W3136139429 sameAs 3136139429 @default.
- W3136139429 citedByCount "3" @default.
- W3136139429 countsByYear W31361394292021 @default.
- W3136139429 countsByYear W31361394292022 @default.
- W3136139429 crossrefType "posted-content" @default.
- W3136139429 hasAuthorship W3136139429A5069648079 @default.
- W3136139429 hasAuthorship W3136139429A5079386554 @default.
- W3136139429 hasAuthorship W3136139429A5087866299 @default.
- W3136139429 hasBestOaLocation W31361394291 @default.
- W3136139429 hasConcept C126838900 @default.
- W3136139429 hasConcept C142724271 @default.
- W3136139429 hasConcept C143409427 @default.
- W3136139429 hasConcept C149550507 @default.
- W3136139429 hasConcept C153180895 @default.
- W3136139429 hasConcept C154945302 @default.
- W3136139429 hasConcept C169760540 @default.
- W3136139429 hasConcept C2779130545 @default.
- W3136139429 hasConcept C2781192897 @default.
- W3136139429 hasConcept C41008148 @default.
- W3136139429 hasConcept C54170458 @default.
- W3136139429 hasConcept C71924100 @default.
- W3136139429 hasConcept C84787856 @default.
- W3136139429 hasConcept C86803240 @default.
- W3136139429 hasConceptScore W3136139429C126838900 @default.
- W3136139429 hasConceptScore W3136139429C142724271 @default.
- W3136139429 hasConceptScore W3136139429C143409427 @default.
- W3136139429 hasConceptScore W3136139429C149550507 @default.
- W3136139429 hasConceptScore W3136139429C153180895 @default.
- W3136139429 hasConceptScore W3136139429C154945302 @default.
- W3136139429 hasConceptScore W3136139429C169760540 @default.
- W3136139429 hasConceptScore W3136139429C2779130545 @default.
- W3136139429 hasConceptScore W3136139429C2781192897 @default.
- W3136139429 hasConceptScore W3136139429C41008148 @default.
- W3136139429 hasConceptScore W3136139429C54170458 @default.
- W3136139429 hasConceptScore W3136139429C71924100 @default.
- W3136139429 hasConceptScore W3136139429C84787856 @default.
- W3136139429 hasConceptScore W3136139429C86803240 @default.
- W3136139429 hasLocation W31361394291 @default.
- W3136139429 hasOpenAccess W3136139429 @default.
- W3136139429 hasPrimaryLocation W31361394291 @default.
- W3136139429 hasRelatedWork W134083710 @default.
- W3136139429 hasRelatedWork W1966036178 @default.
- W3136139429 hasRelatedWork W2012065213 @default.
- W3136139429 hasRelatedWork W2041545311 @default.
- W3136139429 hasRelatedWork W2055612249 @default.
- W3136139429 hasRelatedWork W2085041496 @default.
- W3136139429 hasRelatedWork W2475888236 @default.
- W3136139429 hasRelatedWork W2506178460 @default.
- W3136139429 hasRelatedWork W2753427450 @default.
- W3136139429 hasRelatedWork W3174049805 @default.
- W3136139429 isParatext "false" @default.
- W3136139429 isRetracted "false" @default.
- W3136139429 magId "3136139429" @default.
- W3136139429 workType "article" @default.