Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136149497> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W3136149497 endingPage "071" @default.
- W3136149497 startingPage "069" @default.
- W3136149497 abstract "Abstract Background During 19th century, the Circassians were secluded from their lands and forced to migrate to Ottoman Empire properties. Approximately 2,346 Circassians were exiled from Istanbul to Cyprus Island. During the deportation journey, many of Circassian passed away in consequence of malaria and unknown reasons. Overall, 1,351 survivor Circassians managed to reach the island, however, many of them had faced with endemic malaria again in Cyprus. An autosomal recessive hematological disorder thalassemia was the second endemic health condition after malaria, whereas thalassemia carriers show resistance to malaria infections. Materials and Methods A large Cypriot family with 57 members whose grandparents were supposed to be in that ship journey has been investigated in this study. Polymerase chain reaction (PCR)–amplification refractory mutation system (ARMS) analysis technique was used for genotyping the HHB gene. Results The human β-globin (HBB) gene c.316–106C > G (IVS-II-745) (II-745) heterozygous variation have been detected. Conclusion Overall, this study is a very good example for a typical natural selection. In this case, one single gene point mutation did not limit survival in the society; natively, it increased their survival changes to form new colonization and the inheritance of the mutation to the next generations." @default.
- W3136149497 created "2021-03-29" @default.
- W3136149497 creator A5007697614 @default.
- W3136149497 creator A5051448503 @default.
- W3136149497 creator A5069666764 @default.
- W3136149497 creator A5081967935 @default.
- W3136149497 date "2021-03-16" @default.
- W3136149497 modified "2023-09-27" @default.
- W3136149497 title "The Story of a Ship Journey, Malaria, and the HBB Gene IVS-II-745 Mutation: Circassian Immigration to Cyprus" @default.
- W3136149497 cites W1974119586 @default.
- W3136149497 cites W1985830102 @default.
- W3136149497 cites W1988206524 @default.
- W3136149497 cites W2023374624 @default.
- W3136149497 cites W2043490826 @default.
- W3136149497 cites W2107325655 @default.
- W3136149497 cites W2120441099 @default.
- W3136149497 cites W2405830484 @default.
- W3136149497 doi "https://doi.org/10.1055/s-0041-1726336" @default.
- W3136149497 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8110339" @default.
- W3136149497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33987626" @default.
- W3136149497 hasPublicationYear "2021" @default.
- W3136149497 type Work @default.
- W3136149497 sameAs 3136149497 @default.
- W3136149497 citedByCount "0" @default.
- W3136149497 crossrefType "journal-article" @default.
- W3136149497 hasAuthorship W3136149497A5007697614 @default.
- W3136149497 hasAuthorship W3136149497A5051448503 @default.
- W3136149497 hasAuthorship W3136149497A5069666764 @default.
- W3136149497 hasAuthorship W3136149497A5081967935 @default.
- W3136149497 hasBestOaLocation W31361494971 @default.
- W3136149497 hasConcept C104317684 @default.
- W3136149497 hasConcept C135763542 @default.
- W3136149497 hasConcept C144024400 @default.
- W3136149497 hasConcept C149923435 @default.
- W3136149497 hasConcept C166957645 @default.
- W3136149497 hasConcept C203014093 @default.
- W3136149497 hasConcept C205649164 @default.
- W3136149497 hasConcept C2777799968 @default.
- W3136149497 hasConcept C2778048844 @default.
- W3136149497 hasConcept C31467283 @default.
- W3136149497 hasConcept C501734568 @default.
- W3136149497 hasConcept C54355233 @default.
- W3136149497 hasConcept C60961049 @default.
- W3136149497 hasConcept C70036468 @default.
- W3136149497 hasConcept C86803240 @default.
- W3136149497 hasConceptScore W3136149497C104317684 @default.
- W3136149497 hasConceptScore W3136149497C135763542 @default.
- W3136149497 hasConceptScore W3136149497C144024400 @default.
- W3136149497 hasConceptScore W3136149497C149923435 @default.
- W3136149497 hasConceptScore W3136149497C166957645 @default.
- W3136149497 hasConceptScore W3136149497C203014093 @default.
- W3136149497 hasConceptScore W3136149497C205649164 @default.
- W3136149497 hasConceptScore W3136149497C2777799968 @default.
- W3136149497 hasConceptScore W3136149497C2778048844 @default.
- W3136149497 hasConceptScore W3136149497C31467283 @default.
- W3136149497 hasConceptScore W3136149497C501734568 @default.
- W3136149497 hasConceptScore W3136149497C54355233 @default.
- W3136149497 hasConceptScore W3136149497C60961049 @default.
- W3136149497 hasConceptScore W3136149497C70036468 @default.
- W3136149497 hasConceptScore W3136149497C86803240 @default.
- W3136149497 hasIssue "02" @default.
- W3136149497 hasLocation W31361494971 @default.
- W3136149497 hasLocation W31361494972 @default.
- W3136149497 hasOpenAccess W3136149497 @default.
- W3136149497 hasPrimaryLocation W31361494971 @default.
- W3136149497 hasRelatedWork W1562693820 @default.
- W3136149497 hasRelatedWork W1836753393 @default.
- W3136149497 hasRelatedWork W1895018249 @default.
- W3136149497 hasRelatedWork W2068588654 @default.
- W3136149497 hasRelatedWork W2109451199 @default.
- W3136149497 hasRelatedWork W2135257384 @default.
- W3136149497 hasRelatedWork W2260169894 @default.
- W3136149497 hasRelatedWork W2384774992 @default.
- W3136149497 hasRelatedWork W4315629143 @default.
- W3136149497 hasRelatedWork W631795973 @default.
- W3136149497 hasVolume "08" @default.
- W3136149497 isParatext "false" @default.
- W3136149497 isRetracted "false" @default.
- W3136149497 magId "3136149497" @default.
- W3136149497 workType "article" @default.