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• W3136152072 startingPage "929" @default.
• W3136152072 abstract "Owing to its superior water absorption capacity, superabsorbent polymer (SAP) based on a poly (acrylic acid) network is extensively used in industrial products such as diapers, wound dressing, or surgical pads. However, because SAP does not degrade naturally, a massive amount of non-degradable waste is discarded daily, posing serious environmental problems. Considering that diapers are the most widely used end-product of SAP, we created one that is degradable by a human urinary enzyme. We chose three enzyme candidates, all of which have substrates that were modified with polymerizable groups to be examined for cleavable crosslinkers of SAP. We found that the urokinase-type plasminogen activator (uPA) substrate, end-modified with acrylamide groups at sufficient distances from the enzymatic cleavage site, can be successfully used as a cleavable crosslinker of SAP. The resulting SAP slowly degraded over several days in the aqueous solution containing uPA at a physiological concentration found in human urine and became shapeless in ~30 days." @default.
• W3136152072 created "2021-03-29" @default.
• W3136152072 creator A5014299141 @default.
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• W3136152072 date "2021-03-17" @default.
• W3136152072 modified "2023-09-27" @default.
• W3136152072 title "Superabsorbent Polymer Network Degradable by a Human Urinary Enzyme" @default.
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• W3136152072 doi "https://doi.org/10.3390/polym13060929" @default.
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