FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136169294> ?p ?o ?g. }

• W3136169294 abstract "Abstract Background Eukaryote genomes frequently harbor supernumerary B chromosomes in addition to the “standard” A chromosome set. B chromosomes are thought to arise as byproducts of genome rearrangements and have mostly been considered intraspecific oddities. However, their evolutionary transcendence beyond species level has remained untested. Results Here we reveal that the large metacentric B chromosomes reported in several fish species of the genus Astyanax arose in a common ancestor at least 4 million years ago. We generated transcriptomes of A. scabripinnis and A. paranae 0B and 1B individuals and used these assemblies as a reference for mapping all gDNA and RNA libraries to quantify coverage differences between B-lacking and B-carrying genomes. We show that the B chromosomes of A. scabripinnis and A. paranae share 19 protein-coding genes, of which 14 and 11 were also present in the B chromosomes of A. bockmanni and A. fasciatus , respectively. Our search for B-specific single-nucleotide polymorphisms (SNPs) identified the presence of B-derived transcripts in B-carrying ovaries, 80% of which belonged to nobox , a gene involved in oogenesis regulation. Importantly, the B chromosome nobox paralog is expressed > 30× more than the A chromosome paralog. This indicates that the normal regulation of this gene is altered in B-carrying females, which could potentially facilitate B inheritance at higher rates than Mendelian law prediction. Conclusions Taken together, our results demonstrate the long-term survival of B chromosomes despite their lack of regular pairing and segregation during meiosis and that they can endure episodes of population divergence leading to species formation." @default.
• W3136169294 created "2021-03-29" @default.
• W3136169294 creator A5029842594 @default.
• W3136169294 creator A5036696248 @default.
• W3136169294 creator A5038969481 @default.
• W3136169294 creator A5041200276 @default.
• W3136169294 creator A5053443859 @default.
• W3136169294 creator A5053700120 @default.
• W3136169294 creator A5068341780 @default.
• W3136169294 creator A5071742653 @default.
• W3136169294 creator A5073364328 @default.
• W3136169294 creator A5073509953 @default.
• W3136169294 creator A5075534410 @default.
• W3136169294 creator A5077055220 @default.
• W3136169294 creator A5077669562 @default.
• W3136169294 creator A5088581760 @default.
• W3136169294 date "2021-03-19" @default.
• W3136169294 modified "2023-10-18" @default.
• W3136169294 title "Long-term persistence of supernumerary B chromosomes in multiple species of Astyanax fish" @default.
• W3136169294 cites W130804182 @default.
• W3136169294 cites W1411064714 @default.
• W3136169294 cites W1507784575 @default.
• W3136169294 cites W1526341273 @default.
• W3136169294 cites W1813860635 @default.
• W3136169294 cites W1969264427 @default.
• W3136169294 cites W1970973227 @default.
• W3136169294 cites W1979831442 @default.
• W3136169294 cites W1983682804 @default.
• W3136169294 cites W1986098668 @default.
• W3136169294 cites W1995109463 @default.
• W3136169294 cites W1996889845 @default.
• W3136169294 cites W1997241567 @default.
• W3136169294 cites W2000961959 @default.
• W3136169294 cites W2003972150 @default.
• W3136169294 cites W2011657487 @default.
• W3136169294 cites W2012912155 @default.
• W3136169294 cites W2013007044 @default.
• W3136169294 cites W2018144419 @default.
• W3136169294 cites W2023345960 @default.
• W3136169294 cites W2027131349 @default.
• W3136169294 cites W2032281322 @default.
• W3136169294 cites W2032412658 @default.
• W3136169294 cites W2043879337 @default.
• W3136169294 cites W2045175915 @default.
• W3136169294 cites W2048463417 @default.
• W3136169294 cites W2050163580 @default.
• W3136169294 cites W2050832931 @default.
• W3136169294 cites W2051902571 @default.
• W3136169294 cites W2054960781 @default.
• W3136169294 cites W2055043387 @default.
• W3136169294 cites W2056009248 @default.
• W3136169294 cites W2056688430 @default.
• W3136169294 cites W2061874742 @default.
• W3136169294 cites W2064194489 @default.
• W3136169294 cites W2083364153 @default.
• W3136169294 cites W2086798639 @default.
• W3136169294 cites W2091988250 @default.
• W3136169294 cites W2104312285 @default.
• W3136169294 cites W2107277218 @default.
• W3136169294 cites W2108234281 @default.
• W3136169294 cites W2110835349 @default.
• W3136169294 cites W2125027155 @default.
• W3136169294 cites W2129892332 @default.
• W3136169294 cites W2131584682 @default.
• W3136169294 cites W2142619120 @default.
• W3136169294 cites W2144857015 @default.
• W3136169294 cites W2152905141 @default.
• W3136169294 cites W2156125289 @default.
• W3136169294 cites W2158589954 @default.
• W3136169294 cites W2158596411 @default.
• W3136169294 cites W2158804744 @default.
• W3136169294 cites W2159957100 @default.
• W3136169294 cites W2160378127 @default.
• W3136169294 cites W2162098634 @default.
• W3136169294 cites W2164154943 @default.
• W3136169294 cites W2164271264 @default.
• W3136169294 cites W2166120425 @default.
• W3136169294 cites W2176906216 @default.
• W3136169294 cites W2260045688 @default.
• W3136169294 cites W2297731476 @default.
• W3136169294 cites W2556696447 @default.
• W3136169294 cites W2567514794 @default.
• W3136169294 cites W2604196160 @default.
• W3136169294 cites W2623519628 @default.
• W3136169294 cites W2758644456 @default.
• W3136169294 cites W2801159594 @default.
• W3136169294 cites W2898255300 @default.
• W3136169294 cites W2904427482 @default.
• W3136169294 cites W2950119471 @default.
• W3136169294 cites W2952837230 @default.
• W3136169294 cites W2954540077 @default.
• W3136169294 cites W2991383315 @default.
• W3136169294 cites W2997741234 @default.
• W3136169294 cites W3014180560 @default.
• W3136169294 cites W3087838994 @default.
• W3136169294 cites W4247492703 @default.
• W3136169294 doi "https://doi.org/10.1186/s12915-021-00991-9" @default.
• W3136169294 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7976721" @default.
• W3136169294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33740955" @default.
• W3136169294 hasPublicationYear "2021" @default.

• next