Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136194905> ?p ?o ?g. }
- W3136194905 endingPage "1606" @default.
- W3136194905 startingPage "1596" @default.
- W3136194905 abstract "The presence of antibodies against endemic coronaviruses has been linked to disease severity after SARS-CoV-2 infection. Assays capable of concomitantly detecting antibodies against endemic coronaviridae such as OC43, 229E, NL63, and SARS-CoV-2 may help to elucidate this question. We developed a serum screening platform using a bead-based Western blot system called DigiWest, capable of running hundreds of assays using microgram amounts of protein prepared directly from different viruses. Characterization of the immunoassay for detection of SARS-CoV-2 specific antibodies revealed a sensitivity of 90.3% and a diagnostic specificity of 98.1%. Concordance analysis with the SARS-CoV-2 immunoassays available by Roche, Siemens, and Euroimmun indicates comparable assay performances (Cohen’s κ ranging from 0.8874 to 0.9508). Analogous assays for OC43, 229E, and NL63 were established and combined into one multiplex with the SARS-CoV-2 assay. Seroreactivity for different coronaviruses was detected with high incidence, and the multiplex assay was adapted for serum screening." @default.
- W3136194905 created "2021-03-29" @default.
- W3136194905 creator A5006267026 @default.
- W3136194905 creator A5006282362 @default.
- W3136194905 creator A5017065625 @default.
- W3136194905 creator A5017998451 @default.
- W3136194905 creator A5020573475 @default.
- W3136194905 creator A5020673989 @default.
- W3136194905 creator A5022087100 @default.
- W3136194905 creator A5025026489 @default.
- W3136194905 creator A5030389428 @default.
- W3136194905 creator A5035343659 @default.
- W3136194905 creator A5037039636 @default.
- W3136194905 creator A5048584651 @default.
- W3136194905 creator A5058234708 @default.
- W3136194905 creator A5058726143 @default.
- W3136194905 creator A5059556502 @default.
- W3136194905 creator A5060216300 @default.
- W3136194905 creator A5070896162 @default.
- W3136194905 creator A5079441890 @default.
- W3136194905 creator A5080106313 @default.
- W3136194905 creator A5085570746 @default.
- W3136194905 creator A5088161106 @default.
- W3136194905 date "2021-03-16" @default.
- W3136194905 modified "2023-09-25" @default.
- W3136194905 title "Multiplexed Serum Antibody Screening Platform Using Virus Extracts from Endemic <i>Coronaviridae</i> and SARS-CoV-2" @default.
- W3136194905 cites W2020070069 @default.
- W3136194905 cites W2111817213 @default.
- W3136194905 cites W2132346896 @default.
- W3136194905 cites W2521489366 @default.
- W3136194905 cites W3003217347 @default.
- W3136194905 cites W3004896487 @default.
- W3136194905 cites W3007929363 @default.
- W3136194905 cites W3008090866 @default.
- W3136194905 cites W3010074729 @default.
- W3136194905 cites W3017376323 @default.
- W3136194905 cites W3024554369 @default.
- W3136194905 cites W3025320502 @default.
- W3136194905 cites W3025631553 @default.
- W3136194905 cites W3030877763 @default.
- W3136194905 cites W3033938970 @default.
- W3136194905 cites W3036931136 @default.
- W3136194905 cites W3040725637 @default.
- W3136194905 cites W3041283001 @default.
- W3136194905 cites W3041450977 @default.
- W3136194905 cites W3046765517 @default.
- W3136194905 cites W3047159181 @default.
- W3136194905 cites W3047706242 @default.
- W3136194905 cites W3087128437 @default.
- W3136194905 cites W3089759643 @default.
- W3136194905 cites W3091214020 @default.
- W3136194905 cites W3096867322 @default.
- W3136194905 cites W3131755888 @default.
- W3136194905 cites W4294214983 @default.
- W3136194905 doi "https://doi.org/10.1021/acsinfecdis.0c00725" @default.
- W3136194905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8101008" @default.
- W3136194905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33724771" @default.
- W3136194905 hasPublicationYear "2021" @default.
- W3136194905 type Work @default.
- W3136194905 sameAs 3136194905 @default.
- W3136194905 citedByCount "5" @default.
- W3136194905 countsByYear W31361949052021 @default.
- W3136194905 countsByYear W31361949052022 @default.
- W3136194905 countsByYear W31361949052023 @default.
- W3136194905 crossrefType "journal-article" @default.
- W3136194905 hasAuthorship W3136194905A5006267026 @default.
- W3136194905 hasAuthorship W3136194905A5006282362 @default.
- W3136194905 hasAuthorship W3136194905A5017065625 @default.
- W3136194905 hasAuthorship W3136194905A5017998451 @default.
- W3136194905 hasAuthorship W3136194905A5020573475 @default.
- W3136194905 hasAuthorship W3136194905A5020673989 @default.
- W3136194905 hasAuthorship W3136194905A5022087100 @default.
- W3136194905 hasAuthorship W3136194905A5025026489 @default.
- W3136194905 hasAuthorship W3136194905A5030389428 @default.
- W3136194905 hasAuthorship W3136194905A5035343659 @default.
- W3136194905 hasAuthorship W3136194905A5037039636 @default.
- W3136194905 hasAuthorship W3136194905A5048584651 @default.
- W3136194905 hasAuthorship W3136194905A5058234708 @default.
- W3136194905 hasAuthorship W3136194905A5058726143 @default.
- W3136194905 hasAuthorship W3136194905A5059556502 @default.
- W3136194905 hasAuthorship W3136194905A5060216300 @default.
- W3136194905 hasAuthorship W3136194905A5070896162 @default.
- W3136194905 hasAuthorship W3136194905A5079441890 @default.
- W3136194905 hasAuthorship W3136194905A5080106313 @default.
- W3136194905 hasAuthorship W3136194905A5085570746 @default.
- W3136194905 hasAuthorship W3136194905A5088161106 @default.
- W3136194905 hasBestOaLocation W31361949051 @default.
- W3136194905 hasConcept C104317684 @default.
- W3136194905 hasConcept C142724271 @default.
- W3136194905 hasConcept C153911025 @default.
- W3136194905 hasConcept C159047783 @default.
- W3136194905 hasConcept C159654299 @default.
- W3136194905 hasConcept C203014093 @default.
- W3136194905 hasConcept C2776415932 @default.
- W3136194905 hasConcept C2776844884 @default.
- W3136194905 hasConcept C2777648638 @default.
- W3136194905 hasConcept C2779134260 @default.
- W3136194905 hasConcept C2780420688 @default.