FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136201537> ?p ?o ?g. }

• W3136201537 endingPage "111696" @default.
• W3136201537 startingPage "111696" @default.
• W3136201537 abstract "The importance of macromolecules paves the way towards a detailed molecular level investigation as all most all cellular processes occurring at the interior of cells in the form of proteins, enzymes, and other biological molecules are significantly affected because of their crowding. Thus, exploring the role of crowding environment on the denaturation and renaturation kinetics of protein molecules is of great importance. Here, CRABP I (cellular retinoic acid binding protein I) is employed as a model protein along with different molecular weights of Polyethylene glycol (PEG) as molecular crowders. The experimental evaluations are done by accessing the protein secondary structure analysis using circular dichroism (CD) spectroscopy and unfolding kinetics using intrinsic fluorescence of CRABP I at 37 °C to mimic the in vivo crowding environment. The unfolding kinetics results indicated that both PEG 2000 and PEG 4000 act as stabilizers by retarding the unfolding kinetic rates. Both kinetic and stability outcomes presented the importance of crowding environment on stability and kinetics of CRABP I. The molecular dynamics (MD) studies revealed that thirteen PEG 2000 molecules assembled during the 500 ns simulation, which increases the stability and percentage of β-sheet. The experimental findings are well supported by the molecular dynamics simulation results." @default.
• W3136201537 created "2021-03-29" @default.
• W3136201537 creator A5024442050 @default.
• W3136201537 creator A5028294599 @default.
• W3136201537 creator A5051383694 @default.
• W3136201537 creator A5084461060 @default.
• W3136201537 date "2021-06-01" @default.
• W3136201537 modified "2023-10-06" @default.
• W3136201537 title "Polyethylene glycol perturbs the unfolding of CRABP I: A correlation between experimental and theoretical approach" @default.
• W3136201537 cites W1965051751 @default.
• W3136201537 cites W1976488701 @default.
• W3136201537 cites W1981021420 @default.
• W3136201537 cites W1991346168 @default.
• W3136201537 cites W1995700633 @default.
• W3136201537 cites W1995816895 @default.
• W3136201537 cites W2010084208 @default.
• W3136201537 cites W2010921894 @default.
• W3136201537 cites W2016069760 @default.
• W3136201537 cites W2016081971 @default.
• W3136201537 cites W2025817849 @default.
• W3136201537 cites W2027913596 @default.
• W3136201537 cites W2034763972 @default.
• W3136201537 cites W2036854355 @default.
• W3136201537 cites W2043680686 @default.
• W3136201537 cites W2060222676 @default.
• W3136201537 cites W2060872711 @default.
• W3136201537 cites W2065208158 @default.
• W3136201537 cites W2069122773 @default.
• W3136201537 cites W2076121886 @default.
• W3136201537 cites W2081457168 @default.
• W3136201537 cites W2084572582 @default.
• W3136201537 cites W2085519055 @default.
• W3136201537 cites W2091967731 @default.
• W3136201537 cites W2096898733 @default.
• W3136201537 cites W2104017463 @default.
• W3136201537 cites W2132589721 @default.
• W3136201537 cites W2150766477 @default.
• W3136201537 cites W2152284567 @default.
• W3136201537 cites W2161636675 @default.
• W3136201537 cites W2164907095 @default.
• W3136201537 cites W263380825 @default.
• W3136201537 cites W2747715328 @default.
• W3136201537 cites W2754219958 @default.
• W3136201537 cites W2894639568 @default.
• W3136201537 cites W3092037569 @default.
• W3136201537 doi "https://doi.org/10.1016/j.colsurfb.2021.111696" @default.
• W3136201537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33770701" @default.
• W3136201537 hasPublicationYear "2021" @default.
• W3136201537 type Work @default.
• W3136201537 sameAs 3136201537 @default.
• W3136201537 citedByCount "1" @default.
• W3136201537 countsByYear W31362015372022 @default.
• W3136201537 crossrefType "journal-article" @default.
• W3136201537 hasAuthorship W3136201537A5024442050 @default.
• W3136201537 hasAuthorship W3136201537A5028294599 @default.
• W3136201537 hasAuthorship W3136201537A5051383694 @default.
• W3136201537 hasAuthorship W3136201537A5084461060 @default.
• W3136201537 hasConcept C10138342 @default.
• W3136201537 hasConcept C121332964 @default.
• W3136201537 hasConcept C12554922 @default.
• W3136201537 hasConcept C133571119 @default.
• W3136201537 hasConcept C13965031 @default.
• W3136201537 hasConcept C144618238 @default.
• W3136201537 hasConcept C147597530 @default.
• W3136201537 hasConcept C148898269 @default.
• W3136201537 hasConcept C162324750 @default.
• W3136201537 hasConcept C178790620 @default.
• W3136201537 hasConcept C181990884 @default.
• W3136201537 hasConcept C185592680 @default.
• W3136201537 hasConcept C204328495 @default.
• W3136201537 hasConcept C204389451 @default.
• W3136201537 hasConcept C2776923230 @default.
• W3136201537 hasConcept C2776964284 @default.
• W3136201537 hasConcept C32909587 @default.
• W3136201537 hasConcept C54400483 @default.
• W3136201537 hasConcept C55493867 @default.
• W3136201537 hasConcept C59593255 @default.
• W3136201537 hasConcept C62520636 @default.
• W3136201537 hasConcept C62614982 @default.
• W3136201537 hasConcept C8010536 @default.
• W3136201537 hasConcept C86803240 @default.
• W3136201537 hasConceptScore W3136201537C10138342 @default.
• W3136201537 hasConceptScore W3136201537C121332964 @default.
• W3136201537 hasConceptScore W3136201537C12554922 @default.
• W3136201537 hasConceptScore W3136201537C133571119 @default.
• W3136201537 hasConceptScore W3136201537C13965031 @default.
• W3136201537 hasConceptScore W3136201537C144618238 @default.
• W3136201537 hasConceptScore W3136201537C147597530 @default.
• W3136201537 hasConceptScore W3136201537C148898269 @default.
• W3136201537 hasConceptScore W3136201537C162324750 @default.
• W3136201537 hasConceptScore W3136201537C178790620 @default.
• W3136201537 hasConceptScore W3136201537C181990884 @default.
• W3136201537 hasConceptScore W3136201537C185592680 @default.
• W3136201537 hasConceptScore W3136201537C204328495 @default.
• W3136201537 hasConceptScore W3136201537C204389451 @default.
• W3136201537 hasConceptScore W3136201537C2776923230 @default.
• W3136201537 hasConceptScore W3136201537C2776964284 @default.
• W3136201537 hasConceptScore W3136201537C32909587 @default.

• next