FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136207010> ?p ?o ?g. }

• W3136207010 abstract "We describe the chromosomal abnormalities found in 104 previously untreated patients with non-Hodgkin's lymphoma (NHL) and the correlations of these abnormalities with disease characteristics. The cytogenetic method used was a 24- to 48-hour culture, followed by G- banding. Several significant associations were discovered. A trisomy 3 was correlated with high-grade NHL. In the patients with an immunoblastic NHL, an abnormal chromosome no. 3 or 6 was found significantly more frequently. As previously described, a t(14;18) was significantly correlated with a follicular growth pattern. Abnormalities on chromosome no. 17 were correlated with a diffuse histology and a shorter survival. A shorter survival was also correlated with a +5, +6, +18, all abnormalities on chromosome no. 5, or involvement of breakpoint 14q11–12. In a multivariate analysis, these chromosomal abnormalities appeared to be independent prognostic factors and correlated with survival more strongly than any traditional prognostic variable. Patients with a t(11;14)(q13;q32) had an elevated lactate dehydrogenase (LDH). Skin infiltration was correlated with abnormalities on 2p. Abnormalities involving breakpoints 6q11–16 were correlated with B symptoms. Patients with abnormalities involving breakpoints 3q21–25 and 13q21–24 had more frequent bulky disease. The correlations of certain clinical findings with specific chromosomal abnormalities might help unveil the pathogenetic mechanisms of NHL and tailor treatment regimens." @default.
• W3136207010 created "2021-03-29" @default.
• W3136207010 creator A5022164102 @default.
• W3136207010 creator A5028949419 @default.
• W3136207010 creator A5034779401 @default.
• W3136207010 creator A5049270053 @default.
• W3136207010 creator A5061471602 @default.
• W3136207010 date "1990-05-01" @default.
• W3136207010 modified "2023-09-28" @default.
• W3136207010 title "Chromosomal abnormalities in untreated patients with non-Hodgkin's lymphoma: associations with histology, clinical characteristics, and treatment outcome. The Nebraska Lymphoma Study Group" @default.
• W3136207010 cites W1510546584 @default.
• W3136207010 cites W1766242208 @default.
• W3136207010 cites W1840641250 @default.
• W3136207010 cites W1911120442 @default.
• W3136207010 cites W1966059563 @default.
• W3136207010 cites W1973223874 @default.
• W3136207010 cites W1979300931 @default.
• W3136207010 cites W1996616160 @default.
• W3136207010 cites W2003351228 @default.
• W3136207010 cites W2036036317 @default.
• W3136207010 cites W2041089085 @default.
• W3136207010 cites W2057796341 @default.
• W3136207010 cites W2067806450 @default.
• W3136207010 cites W2073243844 @default.
• W3136207010 cites W2093193204 @default.
• W3136207010 cites W2096501569 @default.
• W3136207010 cites W2150290224 @default.
• W3136207010 cites W2157198284 @default.
• W3136207010 cites W2225668169 @default.
• W3136207010 cites W2258442726 @default.
• W3136207010 cites W2317615904 @default.
• W3136207010 cites W2318225391 @default.
• W3136207010 cites W2336990540 @default.
• W3136207010 cites W2339359539 @default.
• W3136207010 cites W2400925245 @default.
• W3136207010 cites W2415779678 @default.
• W3136207010 cites W2424847179 @default.
• W3136207010 cites W2797407388 @default.
• W3136207010 cites W304227101 @default.
• W3136207010 cites W2995133996 @default.
• W3136207010 doi "https://doi.org/10.1182/blood.v75.9.1841.bloodjournal7591841" @default.
• W3136207010 hasPublicationYear "1990" @default.
• W3136207010 type Work @default.
• W3136207010 sameAs 3136207010 @default.
• W3136207010 citedByCount "21" @default.
• W3136207010 crossrefType "journal-article" @default.
• W3136207010 hasAuthorship W3136207010A5022164102 @default.
• W3136207010 hasAuthorship W3136207010A5028949419 @default.
• W3136207010 hasAuthorship W3136207010A5034779401 @default.
• W3136207010 hasAuthorship W3136207010A5049270053 @default.
• W3136207010 hasAuthorship W3136207010A5061471602 @default.
• W3136207010 hasBestOaLocation W31362070101 @default.
• W3136207010 hasConcept C104317684 @default.
• W3136207010 hasConcept C126322002 @default.
• W3136207010 hasConcept C138626823 @default.
• W3136207010 hasConcept C142724271 @default.
• W3136207010 hasConcept C174475383 @default.
• W3136207010 hasConcept C206936463 @default.
• W3136207010 hasConcept C2776229224 @default.
• W3136207010 hasConcept C2777058707 @default.
• W3136207010 hasConcept C2778476748 @default.
• W3136207010 hasConcept C2779338263 @default.
• W3136207010 hasConcept C30481170 @default.
• W3136207010 hasConcept C53226629 @default.
• W3136207010 hasConcept C54355233 @default.
• W3136207010 hasConcept C57269778 @default.
• W3136207010 hasConcept C57742111 @default.
• W3136207010 hasConcept C71924100 @default.
• W3136207010 hasConcept C86803240 @default.
• W3136207010 hasConcept C90924648 @default.
• W3136207010 hasConceptScore W3136207010C104317684 @default.
• W3136207010 hasConceptScore W3136207010C126322002 @default.
• W3136207010 hasConceptScore W3136207010C138626823 @default.
• W3136207010 hasConceptScore W3136207010C142724271 @default.
• W3136207010 hasConceptScore W3136207010C174475383 @default.
• W3136207010 hasConceptScore W3136207010C206936463 @default.
• W3136207010 hasConceptScore W3136207010C2776229224 @default.
• W3136207010 hasConceptScore W3136207010C2777058707 @default.
• W3136207010 hasConceptScore W3136207010C2778476748 @default.
• W3136207010 hasConceptScore W3136207010C2779338263 @default.
• W3136207010 hasConceptScore W3136207010C30481170 @default.
• W3136207010 hasConceptScore W3136207010C53226629 @default.
• W3136207010 hasConceptScore W3136207010C54355233 @default.
• W3136207010 hasConceptScore W3136207010C57269778 @default.
• W3136207010 hasConceptScore W3136207010C57742111 @default.
• W3136207010 hasConceptScore W3136207010C71924100 @default.
• W3136207010 hasConceptScore W3136207010C86803240 @default.
• W3136207010 hasConceptScore W3136207010C90924648 @default.
• W3136207010 hasLocation W31362070101 @default.
• W3136207010 hasOpenAccess W3136207010 @default.
• W3136207010 hasPrimaryLocation W31362070101 @default.
• W3136207010 hasRelatedWork W1545944643 @default.
• W3136207010 hasRelatedWork W1766242208 @default.
• W3136207010 hasRelatedWork W1784863686 @default.
• W3136207010 hasRelatedWork W1966059563 @default.
• W3136207010 hasRelatedWork W1990430117 @default.
• W3136207010 hasRelatedWork W2012770211 @default.
• W3136207010 hasRelatedWork W2031216320 @default.
• W3136207010 hasRelatedWork W2041089085 @default.
• W3136207010 hasRelatedWork W2049772811 @default.

• next