Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136209912> ?p ?o ?g. }
- W3136209912 endingPage "72" @default.
- W3136209912 startingPage "45" @default.
- W3136209912 abstract "Multiple sclerosis (MS) clusters with the so-called complex genetic diseases, a group of common disorders characterized by modest disease risk heritability and multifaceted gene-environment interactions. The major histocompatibility complex (MHC) is the only genomic region consistently associated with MS, and susceptible MHC haplotypes have been identified. Although the MHC does not account for all genetic contribution to MS, the other genetic contributors have been elusive. Microarray gene-expression studies, which also have not identified a major MS locus, have, however, been promising in elucidating some of the possible pathways involved in the disease. Yet, microarray studies thus far have been unable to separate the genetic causes of MS from the expression consequences of MS. The use of new methodologies and technologies to refine the phenotype, such as brain spectroscopy, PET and functional magnetic resonance imaging combined with novel computational tools and a better understanding of the human genome architecture, may help resolve the genetic causes of MS." @default.
- W3136209912 created "2021-03-29" @default.
- W3136209912 creator A5041195613 @default.
- W3136209912 creator A5088568312 @default.
- W3136209912 date "2008-01-01" @default.
- W3136209912 modified "2023-10-02" @default.
- W3136209912 title "Multiple Sclerosis Genetics" @default.
- W3136209912 cites W114001912 @default.
- W3136209912 cites W1600937528 @default.
- W3136209912 cites W1967591123 @default.
- W3136209912 cites W1969056699 @default.
- W3136209912 cites W1970789556 @default.
- W3136209912 cites W1972495948 @default.
- W3136209912 cites W1973363852 @default.
- W3136209912 cites W1979005856 @default.
- W3136209912 cites W1981714996 @default.
- W3136209912 cites W1981948896 @default.
- W3136209912 cites W1982256565 @default.
- W3136209912 cites W1986720623 @default.
- W3136209912 cites W1989848313 @default.
- W3136209912 cites W1991450386 @default.
- W3136209912 cites W1991842536 @default.
- W3136209912 cites W1991882709 @default.
- W3136209912 cites W1994009925 @default.
- W3136209912 cites W1994198990 @default.
- W3136209912 cites W1994469616 @default.
- W3136209912 cites W1995235123 @default.
- W3136209912 cites W1997011522 @default.
- W3136209912 cites W1997860958 @default.
- W3136209912 cites W1998235450 @default.
- W3136209912 cites W1998963293 @default.
- W3136209912 cites W2000375163 @default.
- W3136209912 cites W2002896714 @default.
- W3136209912 cites W2003116694 @default.
- W3136209912 cites W2004252057 @default.
- W3136209912 cites W2006810082 @default.
- W3136209912 cites W2006952734 @default.
- W3136209912 cites W2012398968 @default.
- W3136209912 cites W2013750281 @default.
- W3136209912 cites W2015554728 @default.
- W3136209912 cites W2015985014 @default.
- W3136209912 cites W2019568999 @default.
- W3136209912 cites W2019926860 @default.
- W3136209912 cites W2020017562 @default.
- W3136209912 cites W2021616480 @default.
- W3136209912 cites W2022421213 @default.
- W3136209912 cites W2022681885 @default.
- W3136209912 cites W2023466265 @default.
- W3136209912 cites W2024180037 @default.
- W3136209912 cites W2024366392 @default.
- W3136209912 cites W2027180135 @default.
- W3136209912 cites W2027587538 @default.
- W3136209912 cites W2028575660 @default.
- W3136209912 cites W2029358621 @default.
- W3136209912 cites W2030883695 @default.
- W3136209912 cites W2031393403 @default.
- W3136209912 cites W2032254195 @default.
- W3136209912 cites W2035117693 @default.
- W3136209912 cites W2036332361 @default.
- W3136209912 cites W2039557568 @default.
- W3136209912 cites W2040007196 @default.
- W3136209912 cites W2041077283 @default.
- W3136209912 cites W2042264889 @default.
- W3136209912 cites W2042300677 @default.
- W3136209912 cites W2043265122 @default.
- W3136209912 cites W2044566129 @default.
- W3136209912 cites W2044835741 @default.
- W3136209912 cites W2045674961 @default.
- W3136209912 cites W2048714660 @default.
- W3136209912 cites W2048887228 @default.
- W3136209912 cites W2050330507 @default.
- W3136209912 cites W2053457637 @default.
- W3136209912 cites W2053769520 @default.
- W3136209912 cites W2054129681 @default.
- W3136209912 cites W2059208857 @default.
- W3136209912 cites W2062374015 @default.
- W3136209912 cites W2069574509 @default.
- W3136209912 cites W2070587287 @default.
- W3136209912 cites W2071641375 @default.
- W3136209912 cites W2071772686 @default.
- W3136209912 cites W2073987596 @default.
- W3136209912 cites W2076322837 @default.
- W3136209912 cites W2076598308 @default.
- W3136209912 cites W2078003492 @default.
- W3136209912 cites W2078831506 @default.
- W3136209912 cites W2080142291 @default.
- W3136209912 cites W2084906622 @default.
- W3136209912 cites W2087553305 @default.
- W3136209912 cites W2089015359 @default.
- W3136209912 cites W2089111295 @default.
- W3136209912 cites W2089593597 @default.
- W3136209912 cites W2090348783 @default.
- W3136209912 cites W2090810305 @default.
- W3136209912 cites W2091625260 @default.
- W3136209912 cites W2094013223 @default.
- W3136209912 cites W2094577549 @default.
- W3136209912 cites W2094848571 @default.
- W3136209912 cites W2096528849 @default.