Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136243081> ?p ?o ?g. }
- W3136243081 endingPage "3068" @default.
- W3136243081 startingPage "3068" @default.
- W3136243081 abstract "RNA-binding proteins (RBPs) are key elements involved in post-transcriptional regulation. Ataxin-2 (ATXN2) is an evolutionarily conserved RBP protein, whose function has been studied in several model organisms, from Saccharomyces cerevisiae to the Homo sapiens. ATXN2 interacts with poly(A) binding proteins (PABP) and binds to specific sequences at the 3′UTR of target mRNAs to stabilize them. CTC-Interacting Domain3 (CID3) and CID4 are two ATXN2 orthologs present in plant genomes whose function is unknown. In the present study, phenotypical and transcriptome profiling were used to examine the role of CID3 and CID4 in Arabidopsis thaliana. We found that they act redundantly to influence pathways throughout the life cycle. cid3cid4 double mutant showed a delay in flowering time and a reduced rosette size. Transcriptome profiling revealed that key factors that promote floral transition and floral meristem identity were downregulated in cid3cid4 whereas the flowering repressor FLOWERING LOCUS C (FLC) was upregulated. Expression of key factors in the photoperiodic regulation of flowering and circadian clock pathways, were also altered in cid3cid4, as well as the expression of several transcription factors and miRNAs encoding genes involved in leaf growth dynamics. These findings reveal that ATXN2 orthologs may have a role in developmental pathways throughout the life cycle of plants." @default.
- W3136243081 created "2021-03-29" @default.
- W3136243081 creator A5003756653 @default.
- W3136243081 creator A5052847528 @default.
- W3136243081 creator A5053565629 @default.
- W3136243081 date "2021-03-17" @default.
- W3136243081 modified "2023-09-26" @default.
- W3136243081 title "The ATXN2 Orthologs CID3 and CID4, Act Redundantly to In-Fluence Developmental Pathways throughout the Life Cycle of Arabidopsis thaliana" @default.
- W3136243081 cites W1527231190 @default.
- W3136243081 cites W1802305671 @default.
- W3136243081 cites W1911402980 @default.
- W3136243081 cites W1943800940 @default.
- W3136243081 cites W1963541985 @default.
- W3136243081 cites W1967400876 @default.
- W3136243081 cites W1971360525 @default.
- W3136243081 cites W1971528547 @default.
- W3136243081 cites W1972399183 @default.
- W3136243081 cites W1976378620 @default.
- W3136243081 cites W1982633651 @default.
- W3136243081 cites W1988142523 @default.
- W3136243081 cites W1989619236 @default.
- W3136243081 cites W1994840640 @default.
- W3136243081 cites W1998182670 @default.
- W3136243081 cites W2016332933 @default.
- W3136243081 cites W2023838441 @default.
- W3136243081 cites W2026374241 @default.
- W3136243081 cites W2028886234 @default.
- W3136243081 cites W2031384804 @default.
- W3136243081 cites W2033759019 @default.
- W3136243081 cites W2037175112 @default.
- W3136243081 cites W2040745508 @default.
- W3136243081 cites W2043438785 @default.
- W3136243081 cites W2057479270 @default.
- W3136243081 cites W2059242491 @default.
- W3136243081 cites W2059746610 @default.
- W3136243081 cites W2072267291 @default.
- W3136243081 cites W2098115340 @default.
- W3136243081 cites W2098732641 @default.
- W3136243081 cites W2105271154 @default.
- W3136243081 cites W2107400450 @default.
- W3136243081 cites W2108663777 @default.
- W3136243081 cites W2111900469 @default.
- W3136243081 cites W2112318170 @default.
- W3136243081 cites W2112542744 @default.
- W3136243081 cites W2112800334 @default.
- W3136243081 cites W2115514152 @default.
- W3136243081 cites W2122657443 @default.
- W3136243081 cites W2123321939 @default.
- W3136243081 cites W2126446831 @default.
- W3136243081 cites W2127826018 @default.
- W3136243081 cites W2130163276 @default.
- W3136243081 cites W2138238880 @default.
- W3136243081 cites W2152876917 @default.
- W3136243081 cites W2153659320 @default.
- W3136243081 cites W2164417370 @default.
- W3136243081 cites W2166608513 @default.
- W3136243081 cites W2166783246 @default.
- W3136243081 cites W2169158245 @default.
- W3136243081 cites W2169343403 @default.
- W3136243081 cites W2183656084 @default.
- W3136243081 cites W2249390313 @default.
- W3136243081 cites W2396556964 @default.
- W3136243081 cites W2397783656 @default.
- W3136243081 cites W2503927726 @default.
- W3136243081 cites W2504891656 @default.
- W3136243081 cites W2543025675 @default.
- W3136243081 cites W2605345061 @default.
- W3136243081 cites W2608445581 @default.
- W3136243081 cites W2620919859 @default.
- W3136243081 cites W2739439475 @default.
- W3136243081 cites W2739960938 @default.
- W3136243081 cites W2741701583 @default.
- W3136243081 cites W2743802253 @default.
- W3136243081 cites W2766911233 @default.
- W3136243081 cites W2769821632 @default.
- W3136243081 cites W2780277676 @default.
- W3136243081 cites W2791822818 @default.
- W3136243081 cites W2802256578 @default.
- W3136243081 cites W2802960899 @default.
- W3136243081 cites W2804294586 @default.
- W3136243081 cites W2804620307 @default.
- W3136243081 cites W2810898071 @default.
- W3136243081 cites W2885548848 @default.
- W3136243081 cites W2886986893 @default.
- W3136243081 cites W2887175528 @default.
- W3136243081 cites W2888221384 @default.
- W3136243081 cites W2898502596 @default.
- W3136243081 cites W2919578616 @default.
- W3136243081 cites W2920750935 @default.
- W3136243081 cites W2929157312 @default.
- W3136243081 cites W2931131092 @default.
- W3136243081 cites W2936163503 @default.
- W3136243081 cites W2936216122 @default.
- W3136243081 cites W2944495243 @default.
- W3136243081 cites W2949745031 @default.
- W3136243081 cites W2951878797 @default.
- W3136243081 cites W2993335633 @default.
- W3136243081 cites W3002033307 @default.