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- W3136244663 abstract "Immune checkpoint inhibitors such as programmed death protein 1/programmed death-ligand 1 and cytotoxic T-lymphocyte–associated protein 4 inhibitors are already playing a central role in the treatment of metastatic renal cell carcinoma. However, they seem to be only effective in a subset of patients, with a high risk of innate and adaptive tumor resistance. Consequently, biomarkers capable of predicting immune treatment efficacy in advanced renal cancer are needed both in the clinical and the experimental setting. We hereby present a brief summary of evidence on the most studied biomarkers in metastatic renal cell carcinoma with a focus on the possible future place of T cell immunoglobulin and mucin domain-3 (TIM-3)." @default.
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- W3136244663 date "2021-06-01" @default.
- W3136244663 modified "2023-10-16" @default.
- W3136244663 title "Biomarkers in renal cell carcinoma: Towards a more selective immune checkpoint inhibition" @default.
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- W3136244663 doi "https://doi.org/10.1016/j.tranon.2021.101071" @default.
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