FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136251402> ?p ?o ?g. }

• W3136251402 abstract "Abstract Neural interfacing nerve fascicles along the splenic neurovascular plexi (SNVP) is needed to better understand the spleen physiology, and for selective neuromodulation of this major organ. However, the small size and anatomical location have proven to be a significant challenge. Here, we use a reduced liquid crystalline graphene oxide (rGO) fiber coated with platinum (Pt) as a super-flexible suture-like electrode to interface multiple SNVP. The Pt-rGO fibers were used as handover knot electrodes over the small plexi, allowing sensitive recording from the splenic nerve (SN) terminal branches. Asymmetric defasciculation of the SN branches was revealed by electron microscopy, and the functional compartmentalization in spleen innervation was evidenced in response to hypoxia and pharmacological modulation of mean arterial pressure. We demonstrate that electrical stimulation of cervical and subdiaphragmatic vagus nerve (VN), evoked direct activity in a subset of SN terminal branches, providing evidence for a direct VN control over the spleen. This notion was supported by tract-tracing of SN branches, revealing an unconventional direct spleen-VN projection. High-performance Pt-rGO fiber electrodes, may be used for the fine neural modulation of other small neurovascular plexi at the point of entry of the organs as a bioelectronic medical alternative." @default.
• W3136251402 created "2021-03-29" @default.
• W3136251402 creator A5042388287 @default.
• W3136251402 creator A5047833962 @default.
• W3136251402 creator A5048421643 @default.
• W3136251402 creator A5074748535 @default.
• W3136251402 creator A5075351027 @default.
• W3136251402 date "2021-03-20" @default.
• W3136251402 modified "2023-09-26" @default.
• W3136251402 title "Platinized graphene fiber electrodes revealed differential activity in terminal splenic neurovascular plexi supporting a direct spleen-vagus communication" @default.
• W3136251402 cites W1907832415 @default.
• W3136251402 cites W1965391095 @default.
• W3136251402 cites W1971283039 @default.
• W3136251402 cites W1983718048 @default.
• W3136251402 cites W1992576502 @default.
• W3136251402 cites W1995525413 @default.
• W3136251402 cites W1996354441 @default.
• W3136251402 cites W2002497947 @default.
• W3136251402 cites W2006097588 @default.
• W3136251402 cites W2007143131 @default.
• W3136251402 cites W2022782996 @default.
• W3136251402 cites W2025042162 @default.
• W3136251402 cites W2027337530 @default.
• W3136251402 cites W2036325748 @default.
• W3136251402 cites W2046775696 @default.
• W3136251402 cites W2059704497 @default.
• W3136251402 cites W2069368135 @default.
• W3136251402 cites W2086946889 @default.
• W3136251402 cites W2097070426 @default.
• W3136251402 cites W2098321969 @default.
• W3136251402 cites W2107705622 @default.
• W3136251402 cites W2140175617 @default.
• W3136251402 cites W2149635908 @default.
• W3136251402 cites W2159374684 @default.
• W3136251402 cites W2262857824 @default.
• W3136251402 cites W2469268362 @default.
• W3136251402 cites W2576421220 @default.
• W3136251402 cites W2755841351 @default.
• W3136251402 cites W2799804041 @default.
• W3136251402 cites W2800689952 @default.
• W3136251402 cites W2908330676 @default.
• W3136251402 cites W2915688989 @default.
• W3136251402 cites W2922217365 @default.
• W3136251402 cites W3013313006 @default.
• W3136251402 cites W3016847514 @default.
• W3136251402 doi "https://doi.org/10.1101/2021.03.19.436189" @default.
• W3136251402 hasPublicationYear "2021" @default.
• W3136251402 type Work @default.
• W3136251402 sameAs 3136251402 @default.
• W3136251402 citedByCount "0" @default.
• W3136251402 crossrefType "posted-content" @default.
• W3136251402 hasAuthorship W3136251402A5042388287 @default.
• W3136251402 hasAuthorship W3136251402A5047833962 @default.
• W3136251402 hasAuthorship W3136251402A5048421643 @default.
• W3136251402 hasAuthorship W3136251402A5074748535 @default.
• W3136251402 hasAuthorship W3136251402A5075351027 @default.
• W3136251402 hasBestOaLocation W31362514021 @default.
• W3136251402 hasConcept C105572291 @default.
• W3136251402 hasConcept C105702510 @default.
• W3136251402 hasConcept C126322002 @default.
• W3136251402 hasConcept C136229726 @default.
• W3136251402 hasConcept C147789679 @default.
• W3136251402 hasConcept C171250308 @default.
• W3136251402 hasConcept C17525397 @default.
• W3136251402 hasConcept C185592680 @default.
• W3136251402 hasConcept C192562407 @default.
• W3136251402 hasConcept C24998067 @default.
• W3136251402 hasConcept C2780931953 @default.
• W3136251402 hasConcept C2781404750 @default.
• W3136251402 hasConcept C30080830 @default.
• W3136251402 hasConcept C71924100 @default.
• W3136251402 hasConceptScore W3136251402C105572291 @default.
• W3136251402 hasConceptScore W3136251402C105702510 @default.
• W3136251402 hasConceptScore W3136251402C126322002 @default.
• W3136251402 hasConceptScore W3136251402C136229726 @default.
• W3136251402 hasConceptScore W3136251402C147789679 @default.
• W3136251402 hasConceptScore W3136251402C171250308 @default.
• W3136251402 hasConceptScore W3136251402C17525397 @default.
• W3136251402 hasConceptScore W3136251402C185592680 @default.
• W3136251402 hasConceptScore W3136251402C192562407 @default.
• W3136251402 hasConceptScore W3136251402C24998067 @default.
• W3136251402 hasConceptScore W3136251402C2780931953 @default.
• W3136251402 hasConceptScore W3136251402C2781404750 @default.
• W3136251402 hasConceptScore W3136251402C30080830 @default.
• W3136251402 hasConceptScore W3136251402C71924100 @default.
• W3136251402 hasLocation W31362514021 @default.
• W3136251402 hasOpenAccess W3136251402 @default.
• W3136251402 hasPrimaryLocation W31362514021 @default.
• W3136251402 hasRelatedWork W1964421154 @default.
• W3136251402 hasRelatedWork W1983577786 @default.
• W3136251402 hasRelatedWork W1986500318 @default.
• W3136251402 hasRelatedWork W2084636046 @default.
• W3136251402 hasRelatedWork W2114926475 @default.
• W3136251402 hasRelatedWork W2275120746 @default.
• W3136251402 hasRelatedWork W2892628825 @default.
• W3136251402 hasRelatedWork W3118071758 @default.
• W3136251402 hasRelatedWork W4283271968 @default.
• W3136251402 hasRelatedWork W4310122315 @default.
• W3136251402 isParatext "false" @default.
• W3136251402 isRetracted "false" @default.

• next