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• W3136255205 abstract "Purpose To assess potential associations between the prevalence of age-related macular degeneration (AMD) and systemic parameters in a Chinese population. Design Cross-sectional study. Methods The Tongren Health Care Study included individuals attending regular health care check-up examinations in the Beijing Tongren Hospital from 2017 to 2019. Detailed medical examinations and ophthalmic examinations were applied, including fundus photography. AMD was evaluated according to the Beckman Initiative guidelines. Results The study included 7,719 participants (mean age: 60.5 ± 8.1 years; range: 50-97 years). The prevalence of any, early, intermediate, and late AMD was 1,607 of 7,719 (20.8%; 95% confidence interval [CI]: 20.1%, 21.9%), 832 of 7,719 (10.8%; 95% CI: 10.1%, 11.5%), 733 of 7,719 (9.5%; 95% CI: 8.9%, 10.2%), and 42 of 7,719 (0.50%; 95% CI: 0.40%, 0.70%), respectively. In multivariate analysis, the prevalence of any AMD increased with higher blood monocyte count (odds ratio [OR]:3.49; 95% CI: 2.26, 5.38; P Conclusion A higher prevalence of early AMD, intermediate AMD, late AMD, and any AMD was associated with a higher peripheral monocyte count. In agreement with previous studies, the observation suggests monocytes playing a role in the pathogenesis of AMD." @default.
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• W3136255205 date "2021-07-01" @default.
• W3136255205 modified "2023-09-23" @default.
• W3136255205 title "Peripheral Monocyte Count and Age-Related Macular Degeneration. The Tongren Health Care Study" @default.
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• W3136255205 doi "https://doi.org/10.1016/j.ajo.2021.03.010" @default.
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