FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136255745> ?p ?o ?g. }

• W3136255745 endingPage "1867" @default.
• W3136255745 startingPage "1858" @default.
• W3136255745 abstract "Long non-coding RNAs (lncRNAs) are widely involved in a variety of biological processes, including epithelial-mesenchymal transition (EMT). In the current study, we found that lncRNA small nucleolar RNA host gene 8 (SNHG8) was tightly correlated with EMT-associated gene signatures, and was down-regulated by Zinc finger E-box-binding homeobox 1 (ZEB1) during EMT progress. Functionally, knockdown of SNHG8 induced EMT in epithelial cells, through destabilizing the CDH1 mRNA dependent on a 17-nucleotide sequence shared by SNHG8 and CDH1. In addition, analysis with public database showed that SNHG8 tended to be down-regulated in different cancer types and the lower expression of SNHG8 predicted poorer prognosis. Taken together, our study reports a ZEB1-repressed lncRNA SNHG8 which is important for stabilizing CDH1 mRNA, thereby maintaining the epithelial status of epithelial cells." @default.
• W3136255745 created "2021-03-29" @default.
• W3136255745 creator A5017175637 @default.
• W3136255745 creator A5075596275 @default.
• W3136255745 creator A5081933089 @default.
• W3136255745 creator A5089489848 @default.
• W3136255745 date "2021-03-18" @default.
• W3136255745 modified "2023-09-26" @default.
• W3136255745 title "Loss of lncRNA SNHG8 promotes epithelial-mesenchymal transition by destabilizing CDH1 mRNA" @default.
• W3136255745 cites W1964212105 @default.
• W3136255745 cites W1977090021 @default.
• W3136255745 cites W1979026812 @default.
• W3136255745 cites W1981223981 @default.
• W3136255745 cites W1994242450 @default.
• W3136255745 cites W1995480433 @default.
• W3136255745 cites W1996989652 @default.
• W3136255745 cites W2008273587 @default.
• W3136255745 cites W2010231795 @default.
• W3136255745 cites W2012117840 @default.
• W3136255745 cites W2024769280 @default.
• W3136255745 cites W2054574453 @default.
• W3136255745 cites W2056302937 @default.
• W3136255745 cites W2059448294 @default.
• W3136255745 cites W2102284002 @default.
• W3136255745 cites W2104546896 @default.
• W3136255745 cites W2126166557 @default.
• W3136255745 cites W2130410032 @default.
• W3136255745 cites W2130687298 @default.
• W3136255745 cites W2148700019 @default.
• W3136255745 cites W2150585673 @default.
• W3136255745 cites W2155354546 @default.
• W3136255745 cites W2161725244 @default.
• W3136255745 cites W2172312226 @default.
• W3136255745 cites W2178279848 @default.
• W3136255745 cites W2284823004 @default.
• W3136255745 cites W2518100556 @default.
• W3136255745 cites W2617971959 @default.
• W3136255745 cites W2751247278 @default.
• W3136255745 cites W2764013112 @default.
• W3136255745 cites W2793441282 @default.
• W3136255745 cites W2800702047 @default.
• W3136255745 cites W2892230172 @default.
• W3136255745 cites W2905065947 @default.
• W3136255745 cites W2907299724 @default.
• W3136255745 cites W2940057770 @default.
• W3136255745 cites W2947971322 @default.
• W3136255745 cites W2964088941 @default.
• W3136255745 cites W3015714049 @default.
• W3136255745 cites W3024409053 @default.
• W3136255745 cites W3025650229 @default.
• W3136255745 cites W3045747015 @default.
• W3136255745 cites W3046423524 @default.
• W3136255745 doi "https://doi.org/10.1007/s11427-020-1895-2" @default.
• W3136255745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33754289" @default.
• W3136255745 hasPublicationYear "2021" @default.
• W3136255745 type Work @default.
• W3136255745 sameAs 3136255745 @default.
• W3136255745 citedByCount "4" @default.
• W3136255745 countsByYear W31362557452022 @default.
• W3136255745 countsByYear W31362557452023 @default.
• W3136255745 crossrefType "journal-article" @default.
• W3136255745 hasAuthorship W3136255745A5017175637 @default.
• W3136255745 hasAuthorship W3136255745A5075596275 @default.
• W3136255745 hasAuthorship W3136255745A5081933089 @default.
• W3136255745 hasAuthorship W3136255745A5089489848 @default.
• W3136255745 hasBestOaLocation W31362557451 @default.
• W3136255745 hasConcept C104317684 @default.
• W3136255745 hasConcept C105580179 @default.
• W3136255745 hasConcept C121587040 @default.
• W3136255745 hasConcept C1491633281 @default.
• W3136255745 hasConcept C149402561 @default.
• W3136255745 hasConcept C150194340 @default.
• W3136255745 hasConcept C173396325 @default.
• W3136255745 hasConcept C194232998 @default.
• W3136255745 hasConcept C2776391639 @default.
• W3136255745 hasConcept C54355233 @default.
• W3136255745 hasConcept C67705224 @default.
• W3136255745 hasConcept C76419328 @default.
• W3136255745 hasConcept C86803240 @default.
• W3136255745 hasConcept C95444343 @default.
• W3136255745 hasConceptScore W3136255745C104317684 @default.
• W3136255745 hasConceptScore W3136255745C105580179 @default.
• W3136255745 hasConceptScore W3136255745C121587040 @default.
• W3136255745 hasConceptScore W3136255745C1491633281 @default.
• W3136255745 hasConceptScore W3136255745C149402561 @default.
• W3136255745 hasConceptScore W3136255745C150194340 @default.
• W3136255745 hasConceptScore W3136255745C173396325 @default.
• W3136255745 hasConceptScore W3136255745C194232998 @default.
• W3136255745 hasConceptScore W3136255745C2776391639 @default.
• W3136255745 hasConceptScore W3136255745C54355233 @default.
• W3136255745 hasConceptScore W3136255745C67705224 @default.
• W3136255745 hasConceptScore W3136255745C76419328 @default.
• W3136255745 hasConceptScore W3136255745C86803240 @default.
• W3136255745 hasConceptScore W3136255745C95444343 @default.
• W3136255745 hasIssue "11" @default.
• W3136255745 hasLocation W31362557451 @default.
• W3136255745 hasLocation W31362557452 @default.
• W3136255745 hasOpenAccess W3136255745 @default.

• next