Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136257643> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W3136257643 abstract "Background: The accuracy of CT perfusion imaging for estimating the ischemic core has been questioned. Methods: In SELECT, a prospective cohort study of imaging selection, pts who achieved complete reperfusion after EVT were stratified on time from LKW to imaging acquisition and time from imaging to reperfusion. The difference between baseline CTP core volume and f/up infarct volume (on DWI after EVT) was classified as over-estimation (core >10 cc larger than infarct), adequate, or under-estimation (≥ 25 cc smaller). F/up DWI lesion was outlined using a semiautomated algorithm and co-registered to CTP. Results: Of 361 enrolled, 117 achieved TICI 3. F/up MRIs were acquired at 21 (13-30) hrs from EVT with median infarct volume of 16.4 cc, median 8.1 cc larger than baseline core. Median (IQR) time from imaging acquisition to groin puncture (GP) was 70 (50-95) min. Reperfusion was achieved at 35 (25-54) min of GP. The frequency of overestimation decreased as time LKW to imaging increased: < 90 min 6 (14%), 90 – 270 min 3 (6%) and > 270 min 1 (4%), and adequate estimation increased (< 90 min 21 (50%), 90 – 270 min 32 (65%) and > 270min 19 (73%), p for trend 0.048) Fig 1. Overestimation primarily occurred in pts imaged within 90 min who had short imaging to reperfusion times Fig 2. Volumetric correlation between pre-procedure and f/up imaging improved as LKW time to imaging acquisition increased; Spearman’s ρ: <90 min: 0.41 (p=0.007), 90-270 min: 0.35 (p=0.01), >270 min: 0.79 (p<0.0001). Spatially, overestimation occurred predominantly in white matter juxtacortical areas. Adjusting rCBF threshold from < 30% to < 20% in the 6 pts with overestimation ≤ 90 min from LKW resulted in adequate core estimation in all 6, Fig 3. Conclusion: In patients who achieve reperfusion, the correlation between baseline CTP ischemic core volume and f/up DWI volume improved as time LKW to imaging increased. Core estimation accuracy improved by using the < 20% CBF threshold for patients imaged within 90 minutes of LKW." @default.
- W3136257643 created "2021-03-29" @default.
- W3136257643 creator A5000809249 @default.
- W3136257643 creator A5000895141 @default.
- W3136257643 creator A5003937158 @default.
- W3136257643 creator A5009588075 @default.
- W3136257643 creator A5034247564 @default.
- W3136257643 creator A5051404338 @default.
- W3136257643 creator A5074508324 @default.
- W3136257643 creator A5075054318 @default.
- W3136257643 creator A5077135257 @default.
- W3136257643 creator A5079031814 @default.
- W3136257643 date "2021-03-01" @default.
- W3136257643 modified "2023-10-18" @default.
- W3136257643 title "Abstract P331: Accuracy of CT Perfusion Core Estimates for Predicting Infarct Size in the SELECT Study" @default.
- W3136257643 doi "https://doi.org/10.1161/str.52.suppl_1.p331" @default.
- W3136257643 hasPublicationYear "2021" @default.
- W3136257643 type Work @default.
- W3136257643 sameAs 3136257643 @default.
- W3136257643 citedByCount "0" @default.
- W3136257643 crossrefType "journal-article" @default.
- W3136257643 hasAuthorship W3136257643A5000809249 @default.
- W3136257643 hasAuthorship W3136257643A5000895141 @default.
- W3136257643 hasAuthorship W3136257643A5003937158 @default.
- W3136257643 hasAuthorship W3136257643A5009588075 @default.
- W3136257643 hasAuthorship W3136257643A5034247564 @default.
- W3136257643 hasAuthorship W3136257643A5051404338 @default.
- W3136257643 hasAuthorship W3136257643A5074508324 @default.
- W3136257643 hasAuthorship W3136257643A5075054318 @default.
- W3136257643 hasAuthorship W3136257643A5077135257 @default.
- W3136257643 hasAuthorship W3136257643A5079031814 @default.
- W3136257643 hasConcept C126838900 @default.
- W3136257643 hasConcept C135691158 @default.
- W3136257643 hasConcept C146957229 @default.
- W3136257643 hasConcept C2989005 @default.
- W3136257643 hasConcept C71924100 @default.
- W3136257643 hasConceptScore W3136257643C126838900 @default.
- W3136257643 hasConceptScore W3136257643C135691158 @default.
- W3136257643 hasConceptScore W3136257643C146957229 @default.
- W3136257643 hasConceptScore W3136257643C2989005 @default.
- W3136257643 hasConceptScore W3136257643C71924100 @default.
- W3136257643 hasIssue "Suppl_1" @default.
- W3136257643 hasLocation W31362576431 @default.
- W3136257643 hasOpenAccess W3136257643 @default.
- W3136257643 hasPrimaryLocation W31362576431 @default.
- W3136257643 hasRelatedWork W104630177 @default.
- W3136257643 hasRelatedWork W2024932886 @default.
- W3136257643 hasRelatedWork W2168058639 @default.
- W3136257643 hasRelatedWork W2356249032 @default.
- W3136257643 hasRelatedWork W2366627568 @default.
- W3136257643 hasRelatedWork W2382350448 @default.
- W3136257643 hasRelatedWork W2802606979 @default.
- W3136257643 hasRelatedWork W3030916910 @default.
- W3136257643 hasRelatedWork W3032311490 @default.
- W3136257643 hasRelatedWork W3207490395 @default.
- W3136257643 hasVolume "52" @default.
- W3136257643 isParatext "false" @default.
- W3136257643 isRetracted "false" @default.
- W3136257643 magId "3136257643" @default.
- W3136257643 workType "article" @default.