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• W3136285194 abstract "Objectives The true global prevalence of pediatric oral mucosal disease has historically proved difficult to determine, based on heterogeneity and inherent limitations in study designs and a largely descriptive narrative. The 2019 World Workshop on Oral Medicine VII: Relative Frequency of Oral Mucosal Lesions in Children, a Scoping Review quantified pediatric oral mucosal disease experience globally based on pooled and region-specific data from clinical studies and biopsy reports. The aim of this investigation was to retrospectively review clinical data to compare pediatric disease experience in a tertiary joint pediatric-oral medicine clinic at the Royal National ENT and Eastman Dental Hospital, UCLH, London, UK, with published global data from the world workshop. Methods Quantitative analysis was retrospectively performed on recorded clinical data from 22 joint clinics attended between January and December 2018, with recording of patient demographic characteristics, diagnosis, investigations, and management. Results Two hundred sixty-six patients (143 males, 128 females; age range, 8 months to 18 years) were seen in 2018. Referring clinicians included general dental practitioners (n = 54; 49%), secondary care medical and dental specialties (n = 33; 30%), community dental services (n = 15; 14%), and general medical practitioners (n = 9; 8%). Medical comorbidities were noted in 62 patients (23%). Idiopathic recurrent aphthous stomatitis (n = 65; 24%,), mucocele (n = 24; 9%), oral Crohn disease/orofacial granulomatosis (n = 18; 7%), and geographic tongue (n = 11; 4%) were the most commonly presenting conditions. Malignancy was the primary diagnosis in only 1 patient (mucoepidermoid carcinoma). Investigations performed included imaging (n = 27; 11%), blood tests (n = 26; 10%), and biopsy procedures (n = 23; 9%). Management included the use of topical analgesics (n = 71; 27%), topical corticosteroids (n = 94; 35%), topical calcineurin inhibitors (n = 19; 7%), and systemic immunomodulation (n = 22; 8%). Conclusions Similarity to world workshop conclusions was noted, with a predominance of benign oral mucosal disease within this patient demographic. Roughly 1 in 10 patients required investigation by imaging, blood testing, or biopsy. Although the world workshop data represented mostly transient conditions with an infectious or traumatic etiology, within this cohort, there was a greater representation of the oral manifestations of systemic disease, which may well represent the tertiary nature of referral to this unit. The true global prevalence of pediatric oral mucosal disease has historically proved difficult to determine, based on heterogeneity and inherent limitations in study designs and a largely descriptive narrative. The 2019 World Workshop on Oral Medicine VII: Relative Frequency of Oral Mucosal Lesions in Children, a Scoping Review quantified pediatric oral mucosal disease experience globally based on pooled and region-specific data from clinical studies and biopsy reports. The aim of this investigation was to retrospectively review clinical data to compare pediatric disease experience in a tertiary joint pediatric-oral medicine clinic at the Royal National ENT and Eastman Dental Hospital, UCLH, London, UK, with published global data from the world workshop. Quantitative analysis was retrospectively performed on recorded clinical data from 22 joint clinics attended between January and December 2018, with recording of patient demographic characteristics, diagnosis, investigations, and management. Two hundred sixty-six patients (143 males, 128 females; age range, 8 months to 18 years) were seen in 2018. Referring clinicians included general dental practitioners (n = 54; 49%), secondary care medical and dental specialties (n = 33; 30%), community dental services (n = 15; 14%), and general medical practitioners (n = 9; 8%). Medical comorbidities were noted in 62 patients (23%). Idiopathic recurrent aphthous stomatitis (n = 65; 24%,), mucocele (n = 24; 9%), oral Crohn disease/orofacial granulomatosis (n = 18; 7%), and geographic tongue (n = 11; 4%) were the most commonly presenting conditions. Malignancy was the primary diagnosis in only 1 patient (mucoepidermoid carcinoma). Investigations performed included imaging (n = 27; 11%), blood tests (n = 26; 10%), and biopsy procedures (n = 23; 9%). Management included the use of topical analgesics (n = 71; 27%), topical corticosteroids (n = 94; 35%), topical calcineurin inhibitors (n = 19; 7%), and systemic immunomodulation (n = 22; 8%). Similarity to world workshop conclusions was noted, with a predominance of benign oral mucosal disease within this patient demographic. Roughly 1 in 10 patients required investigation by imaging, blood testing, or biopsy. Although the world workshop data represented mostly transient conditions with an infectious or traumatic etiology, within this cohort, there was a greater representation of the oral manifestations of systemic disease, which may well represent the tertiary nature of referral to this unit." @default.
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• W3136285194 date "2021-04-01" @default.
• W3136285194 modified "2023-09-27" @default.
• W3136285194 title "A service evaluation of pediatric oral mucosal disease experience in a tertiary joint pediatric-oral medicine clinic" @default.
• W3136285194 doi "https://doi.org/10.1016/j.oooo.2020.10.054" @default.
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