Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136286353> ?p ?o ?g. }
- W3136286353 endingPage "5096" @default.
- W3136286353 startingPage "5084" @default.
- W3136286353 abstract "Human exposure to microplastic is recognized as a global problem, but the uncertainty, variability, and lifetime accumulation are unresolved. We provide a probabilistic lifetime exposure model for children and adults, which accounts for intake via eight food types and inhalation, intestinal absorption, biliary excretion, and plastic-associated chemical exposure via a physiologically based pharmacokinetic submodel. The model probabilistically simulates microplastic concentrations in the gut, body tissue, and stool, the latter allowing validation against empirical data. Rescaling methods were used to ensure comparability between microplastic abundance data. Microplastic (1–5000 μm) median intake rates are 553 particles/capita/day (184 ng/capita/day) and 883 particles/capita/day (583 ng/capita/day) for children and adults, respectively. This intake can irreversibly accumulate to 8.32 × 103 (90% CI, 7.08 × 102–1.91 × 106) particles/capita or 6.4 (90% CI, 0.1–2.31 × 103) ng/capita for children until age 18, and up to 5.01 × 104 (90% CI, 5.25 × 103–9.33 × 106) particles/capita or 40.7 (90% CI, 0.8–9.85 × 103) ng/capita for adults until age 70 in the body tissue for 1–10 μm particles. Simulated microplastic concentrations in stool agree with empirical data. Chemical absorption from food and ingested microplastic of the nine intake media based on biphasic, reversible, and size-specific sorption kinetics, reveals that the contribution of microplastics to total chemical intake is small. The as-yet-unknown contributions of other food types are discussed in light of future research needs." @default.
- W3136286353 created "2021-03-29" @default.
- W3136286353 creator A5001483262 @default.
- W3136286353 creator A5011772381 @default.
- W3136286353 creator A5012761842 @default.
- W3136286353 creator A5040429015 @default.
- W3136286353 date "2021-03-16" @default.
- W3136286353 modified "2023-10-17" @default.
- W3136286353 title "Lifetime Accumulation of Microplastic in Children and Adults" @default.
- W3136286353 cites W1197379902 @default.
- W3136286353 cites W143133288 @default.
- W3136286353 cites W1735309556 @default.
- W3136286353 cites W1844981334 @default.
- W3136286353 cites W1868126015 @default.
- W3136286353 cites W1918281332 @default.
- W3136286353 cites W1974829426 @default.
- W3136286353 cites W1975077715 @default.
- W3136286353 cites W1979363781 @default.
- W3136286353 cites W1980589942 @default.
- W3136286353 cites W1981644934 @default.
- W3136286353 cites W1983247439 @default.
- W3136286353 cites W1984966262 @default.
- W3136286353 cites W1985760219 @default.
- W3136286353 cites W1990236675 @default.
- W3136286353 cites W1992198528 @default.
- W3136286353 cites W1992390233 @default.
- W3136286353 cites W2001392185 @default.
- W3136286353 cites W2008983008 @default.
- W3136286353 cites W2017291633 @default.
- W3136286353 cites W2021966295 @default.
- W3136286353 cites W2023957562 @default.
- W3136286353 cites W2025808947 @default.
- W3136286353 cites W2027328413 @default.
- W3136286353 cites W2036367387 @default.
- W3136286353 cites W2043653606 @default.
- W3136286353 cites W2045524726 @default.
- W3136286353 cites W2048706353 @default.
- W3136286353 cites W2062054665 @default.
- W3136286353 cites W2064162813 @default.
- W3136286353 cites W2069700706 @default.
- W3136286353 cites W2072529881 @default.
- W3136286353 cites W2074337064 @default.
- W3136286353 cites W2076123156 @default.
- W3136286353 cites W2078048974 @default.
- W3136286353 cites W2078579419 @default.
- W3136286353 cites W2079236889 @default.
- W3136286353 cites W2080068601 @default.
- W3136286353 cites W2087917002 @default.
- W3136286353 cites W2089302309 @default.
- W3136286353 cites W2096209528 @default.
- W3136286353 cites W2096541314 @default.
- W3136286353 cites W2113038310 @default.
- W3136286353 cites W2121346848 @default.
- W3136286353 cites W2123953516 @default.
- W3136286353 cites W2126125179 @default.
- W3136286353 cites W2136829296 @default.
- W3136286353 cites W2139009293 @default.
- W3136286353 cites W2154208403 @default.
- W3136286353 cites W2160446463 @default.
- W3136286353 cites W2162101778 @default.
- W3136286353 cites W2165384969 @default.
- W3136286353 cites W2166292739 @default.
- W3136286353 cites W2181713881 @default.
- W3136286353 cites W2201554425 @default.
- W3136286353 cites W2213772066 @default.
- W3136286353 cites W2300403628 @default.
- W3136286353 cites W2328984514 @default.
- W3136286353 cites W2340862543 @default.
- W3136286353 cites W2414372525 @default.
- W3136286353 cites W2515987409 @default.
- W3136286353 cites W2522138202 @default.
- W3136286353 cites W2594809016 @default.
- W3136286353 cites W2608368045 @default.
- W3136286353 cites W2609177230 @default.
- W3136286353 cites W2620099204 @default.
- W3136286353 cites W2730933369 @default.
- W3136286353 cites W2753938917 @default.
- W3136286353 cites W2761179171 @default.
- W3136286353 cites W2785715629 @default.
- W3136286353 cites W2800589245 @default.
- W3136286353 cites W2806355655 @default.
- W3136286353 cites W2808334666 @default.
- W3136286353 cites W2809114659 @default.
- W3136286353 cites W2809418529 @default.
- W3136286353 cites W2888186731 @default.
- W3136286353 cites W2894937305 @default.
- W3136286353 cites W2895193046 @default.
- W3136286353 cites W2901368925 @default.
- W3136286353 cites W2903763818 @default.
- W3136286353 cites W2908304050 @default.
- W3136286353 cites W2909085130 @default.
- W3136286353 cites W2914940150 @default.
- W3136286353 cites W2918895016 @default.
- W3136286353 cites W2946017099 @default.
- W3136286353 cites W2947607054 @default.
- W3136286353 cites W2948574679 @default.
- W3136286353 cites W2949224266 @default.
- W3136286353 cites W2957777175 @default.