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- W3136292551 abstract "Dear Editor, A 69-year-old male patient presented to the hospital with a 2-month history of systemic myalgia. Previous medical diagnoses included gastric cancer (a distal gastrectomy was performed 17 years prior) and dyslipidaemia on rosuvastatin. Bilateral crackles were heard over chest auscultation. Neurological examinations revealed proximal muscle weakness (manual muscle testing 4/5). Laboratory examinations showed elevated serum levels of the muscle-related enzymes (creatine kinase 814 U/l), cardiac enzymes (troponin I 0.846 ng/ml) and inflammatory markers (CRP 14.9 mg/l). Transthoracic echocardiography revealed mild diastolic dysfunction and pericardial effusion. Chest CT showed subpleural and basal predominant reticular shadows with honeycombing and traction bronchiectasis. Upper gastrointestinal endoscopy revealed advanced gastric cancer in the remnant stomach. A needle EMG study revealed a myopathic pattern. A muscle biopsy on the left biceps muscle returned results consistent with the clinical–serological diagnosis of immune-mediated necrotizing myopathy (IMNM) (Supplementary Fig. 1A–C). The serum was positive..." @default.
- W3136292551 created "2021-03-29" @default.
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- W3136292551 date "2021-03-25" @default.
- W3136292551 modified "2023-10-01" @default.
- W3136292551 title "An autopsy case of anti-hydroxy-3-methylglutaryl-coenzyme A reductase myopathy with involvement of the heart, lungs and respiratory muscles" @default.
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- W3136292551 doi "https://doi.org/10.1093/rheumatology/keab296" @default.
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