Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136303747> ?p ?o ?g. }
- W3136303747 endingPage "95" @default.
- W3136303747 startingPage "86" @default.
- W3136303747 abstract "Infection with HIV-1 remains uncurable due to reservoirs of latently infected cells. Any potential cure for HIV will require a mechanism to identify and target these cells in vivo. We created a panel of Jurkat cell lines latently infected with the HIV DuoFlo virus to identify candidate biomarkers of latency. SWATH mass spectrometry was used to compare the membrane proteomes of one of the cell lines to parental Jurkat cells. Several candidate proteins with significantly altered expression were identified. The differential expression of several candidates was validated in multiple latently infected cell lines. Three factors (LAG-3, CD147,CD231) were altered across numerous cell lines, but the expression of most candidate biomarkers was variable. These results confirm that phenotypic differences in latently infected cells exists and identify additional novel biomarkers. The variable expression of biomarkers across different cell clones suggests universal antigen-based detection of latently infected cells may require a multiplex approach." @default.
- W3136303747 created "2021-03-29" @default.
- W3136303747 creator A5007044731 @default.
- W3136303747 creator A5023892667 @default.
- W3136303747 creator A5052560107 @default.
- W3136303747 creator A5056246963 @default.
- W3136303747 creator A5058220952 @default.
- W3136303747 creator A5063419335 @default.
- W3136303747 creator A5065405324 @default.
- W3136303747 creator A5084075042 @default.
- W3136303747 creator A5089451679 @default.
- W3136303747 date "2021-06-01" @default.
- W3136303747 modified "2023-10-18" @default.
- W3136303747 title "Discovery of candidate HIV-1 latency biomarkers using an OMICs approach" @default.
- W3136303747 cites W1409231956 @default.
- W3136303747 cites W1690275817 @default.
- W3136303747 cites W1961668980 @default.
- W3136303747 cites W1971057735 @default.
- W3136303747 cites W1981440980 @default.
- W3136303747 cites W1989035987 @default.
- W3136303747 cites W1991102201 @default.
- W3136303747 cites W1996076856 @default.
- W3136303747 cites W2001375348 @default.
- W3136303747 cites W2005465321 @default.
- W3136303747 cites W2008426575 @default.
- W3136303747 cites W2010458160 @default.
- W3136303747 cites W2011626958 @default.
- W3136303747 cites W2023404433 @default.
- W3136303747 cites W2027222148 @default.
- W3136303747 cites W2030844138 @default.
- W3136303747 cites W2032440901 @default.
- W3136303747 cites W2036890038 @default.
- W3136303747 cites W2037199116 @default.
- W3136303747 cites W2046854154 @default.
- W3136303747 cites W2053540546 @default.
- W3136303747 cites W2059763409 @default.
- W3136303747 cites W2063628696 @default.
- W3136303747 cites W2066013688 @default.
- W3136303747 cites W2071944732 @default.
- W3136303747 cites W2074130602 @default.
- W3136303747 cites W2081550246 @default.
- W3136303747 cites W2082314789 @default.
- W3136303747 cites W2082803909 @default.
- W3136303747 cites W2088890142 @default.
- W3136303747 cites W2089276164 @default.
- W3136303747 cites W2090646713 @default.
- W3136303747 cites W2091741044 @default.
- W3136303747 cites W2091841926 @default.
- W3136303747 cites W2094434723 @default.
- W3136303747 cites W2100859269 @default.
- W3136303747 cites W2113081839 @default.
- W3136303747 cites W2113282092 @default.
- W3136303747 cites W2121201612 @default.
- W3136303747 cites W2122550753 @default.
- W3136303747 cites W2128208230 @default.
- W3136303747 cites W2131717958 @default.
- W3136303747 cites W2131819621 @default.
- W3136303747 cites W2144697720 @default.
- W3136303747 cites W2147220600 @default.
- W3136303747 cites W2154890740 @default.
- W3136303747 cites W2161345806 @default.
- W3136303747 cites W2171273743 @default.
- W3136303747 cites W2180805750 @default.
- W3136303747 cites W2203560898 @default.
- W3136303747 cites W2240080643 @default.
- W3136303747 cites W2306284315 @default.
- W3136303747 cites W2426204902 @default.
- W3136303747 cites W2462078368 @default.
- W3136303747 cites W2558343753 @default.
- W3136303747 cites W2565673296 @default.
- W3136303747 cites W2595002955 @default.
- W3136303747 cites W2736822140 @default.
- W3136303747 cites W2736848882 @default.
- W3136303747 cites W2762486448 @default.
- W3136303747 cites W2792945463 @default.
- W3136303747 cites W2794937027 @default.
- W3136303747 cites W2797584216 @default.
- W3136303747 cites W2800560571 @default.
- W3136303747 cites W2801428242 @default.
- W3136303747 cites W2893059110 @default.
- W3136303747 cites W2913946693 @default.
- W3136303747 cites W2922220213 @default.
- W3136303747 cites W2923403959 @default.
- W3136303747 cites W2923624122 @default.
- W3136303747 cites W2988692460 @default.
- W3136303747 cites W3089079155 @default.
- W3136303747 cites W4313314629 @default.
- W3136303747 doi "https://doi.org/10.1016/j.virol.2021.03.003" @default.
- W3136303747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33735754" @default.
- W3136303747 hasPublicationYear "2021" @default.
- W3136303747 type Work @default.
- W3136303747 sameAs 3136303747 @default.
- W3136303747 citedByCount "2" @default.
- W3136303747 countsByYear W31363037472022 @default.
- W3136303747 countsByYear W31363037472023 @default.
- W3136303747 crossrefType "journal-article" @default.
- W3136303747 hasAuthorship W3136303747A5007044731 @default.
- W3136303747 hasAuthorship W3136303747A5023892667 @default.