Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136306021> ?p ?o ?g. }
- W3136306021 endingPage "861.e1" @default.
- W3136306021 startingPage "851" @default.
- W3136306021 abstract "Right ventricular (RV) failure in patients with pulmonary hypertension (PH) is associated with unfavorable clinical events and a poor prognosis. Elevation of right atrial (RA) pressure is established as a marker for RV failure. However, the additive prognostic value of RA mechanical function is unclear.The authors tested the hypothesis that RA function by strain echocardiography has prognostic usefulness by studying 165 consecutive patients with precapillary PH defined invasively: mean pulmonary artery pressure ≥ 25 mm Hg and pulmonary capillary wedge pressure < 15 mm Hg. Speckle-tracking strain analyses of the right atrium and right ventricle were performed, along with routine measures. Peak RA strain values from six segments using generic speckle-tracking software were averaged to RA peak longitudinal strain, representing RA global reservoir function. The primary end point was all-cause mortality during 5 years of follow-up. RA strain was similarly analyzed in a control group of 16 normal subjects for comparison.There were 151 patients with PH (mean age, 55 ± 16 years; 73% women; mean World Health Organization functional class, 2.6 ± 0.6), after 14 exclusions (three with atrial septal defects and 11 with left ventricular ejection fractions < 50%). RA strain measurement was feasible in 93% of patients and RV strain measurement in 88%. RA peak longitudinal strain was significantly reduced in patients with PH compared with control subjects, as expected (P < .001). During 5-year follow-up, 73 patients (48%) died. Patients with RA peak strain in the lowest quartile (<25%) had a significant risk for death (P = .006), even after correcting for confounding variables. RA strain was independently associated with survival in multivariate analysis (P = .039) and had additive prognostic value to RV strain (log-rank P = .01) in subgroup analysis.RA peak longitudinal strain had additive prognostic usefulness to other clinical measures, including RV strain, RA area, and RA pressure, in patients with PH. RA mechanical function by strain imaging has potential for clinical applications in patients with PH." @default.
- W3136306021 created "2021-03-29" @default.
- W3136306021 creator A5008768110 @default.
- W3136306021 creator A5021629114 @default.
- W3136306021 creator A5031249497 @default.
- W3136306021 creator A5047964605 @default.
- W3136306021 creator A5053397530 @default.
- W3136306021 creator A5059572789 @default.
- W3136306021 creator A5064388728 @default.
- W3136306021 creator A5066872244 @default.
- W3136306021 creator A5076627885 @default.
- W3136306021 creator A5077886342 @default.
- W3136306021 date "2021-08-01" @default.
- W3136306021 modified "2023-10-11" @default.
- W3136306021 title "The Prognostic Value of Right Atrial Strain Imaging in Patients with Precapillary Pulmonary Hypertension" @default.
- W3136306021 cites W1543475932 @default.
- W3136306021 cites W1572953677 @default.
- W3136306021 cites W175829112 @default.
- W3136306021 cites W1866413456 @default.
- W3136306021 cites W1989584416 @default.
- W3136306021 cites W1994316495 @default.
- W3136306021 cites W2013017465 @default.
- W3136306021 cites W2032885711 @default.
- W3136306021 cites W2051526869 @default.
- W3136306021 cites W2078614820 @default.
- W3136306021 cites W2096546669 @default.
- W3136306021 cites W2119502139 @default.
- W3136306021 cites W2124624517 @default.
- W3136306021 cites W2141987653 @default.
- W3136306021 cites W2161994440 @default.
- W3136306021 cites W2174070261 @default.
- W3136306021 cites W2187630416 @default.
- W3136306021 cites W2277767964 @default.
- W3136306021 cites W2334103823 @default.
- W3136306021 cites W2547822369 @default.
- W3136306021 cites W2596797126 @default.
- W3136306021 cites W2607051096 @default.
- W3136306021 cites W2745943161 @default.
- W3136306021 cites W2787267072 @default.
- W3136306021 cites W2802775615 @default.
- W3136306021 cites W2885889345 @default.
- W3136306021 cites W2890035758 @default.
- W3136306021 cites W2901405337 @default.
- W3136306021 cites W2901518538 @default.
- W3136306021 cites W2942581674 @default.
- W3136306021 cites W2947584571 @default.
- W3136306021 cites W2975748859 @default.
- W3136306021 cites W2990639809 @default.
- W3136306021 cites W2996002032 @default.
- W3136306021 cites W2999685931 @default.
- W3136306021 cites W3012838441 @default.
- W3136306021 cites W3017627152 @default.
- W3136306021 cites W3046544480 @default.
- W3136306021 doi "https://doi.org/10.1016/j.echo.2021.03.007" @default.
- W3136306021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33774108" @default.
- W3136306021 hasPublicationYear "2021" @default.
- W3136306021 type Work @default.
- W3136306021 sameAs 3136306021 @default.
- W3136306021 citedByCount "17" @default.
- W3136306021 countsByYear W31363060212021 @default.
- W3136306021 countsByYear W31363060212022 @default.
- W3136306021 countsByYear W31363060212023 @default.
- W3136306021 crossrefType "journal-article" @default.
- W3136306021 hasAuthorship W3136306021A5008768110 @default.
- W3136306021 hasAuthorship W3136306021A5021629114 @default.
- W3136306021 hasAuthorship W3136306021A5031249497 @default.
- W3136306021 hasAuthorship W3136306021A5047964605 @default.
- W3136306021 hasAuthorship W3136306021A5053397530 @default.
- W3136306021 hasAuthorship W3136306021A5059572789 @default.
- W3136306021 hasAuthorship W3136306021A5064388728 @default.
- W3136306021 hasAuthorship W3136306021A5066872244 @default.
- W3136306021 hasAuthorship W3136306021A5076627885 @default.
- W3136306021 hasAuthorship W3136306021A5077886342 @default.
- W3136306021 hasConcept C126322002 @default.
- W3136306021 hasConcept C146556889 @default.
- W3136306021 hasConcept C164705383 @default.
- W3136306021 hasConcept C2778198053 @default.
- W3136306021 hasConcept C2778296771 @default.
- W3136306021 hasConcept C2778921608 @default.
- W3136306021 hasConcept C2780930700 @default.
- W3136306021 hasConcept C2780940725 @default.
- W3136306021 hasConcept C44249647 @default.
- W3136306021 hasConcept C68443243 @default.
- W3136306021 hasConcept C71924100 @default.
- W3136306021 hasConcept C78085059 @default.
- W3136306021 hasConceptScore W3136306021C126322002 @default.
- W3136306021 hasConceptScore W3136306021C146556889 @default.
- W3136306021 hasConceptScore W3136306021C164705383 @default.
- W3136306021 hasConceptScore W3136306021C2778198053 @default.
- W3136306021 hasConceptScore W3136306021C2778296771 @default.
- W3136306021 hasConceptScore W3136306021C2778921608 @default.
- W3136306021 hasConceptScore W3136306021C2780930700 @default.
- W3136306021 hasConceptScore W3136306021C2780940725 @default.
- W3136306021 hasConceptScore W3136306021C44249647 @default.
- W3136306021 hasConceptScore W3136306021C68443243 @default.
- W3136306021 hasConceptScore W3136306021C71924100 @default.
- W3136306021 hasConceptScore W3136306021C78085059 @default.
- W3136306021 hasFunder F4320309650 @default.