SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136338571> ?p ?o ?g. }

Showing items 1 to 100 of ±193 with 100 items per page.

W3136338571 abstract "Improvement in outcomes of children with acute myeloid leukemia (AML) is attributed to several refinements in clinical management. We evaluated treatment outcomes of Taiwanese pediatric AML patients in the past 20 years. Overall, 860 de novo AML patients aged 0-18 years and registered in the Childhood Cancer Foundation of R.O.C during January 1996-December 2019 were included. Survival analysis was performed to identify factors that improved treatment outcomes. Regardless of treatment modalities used, patients during 2008-2019 had better 5-year event-free survival (EFS) and overall survival (OS) rates than patients during 1996-2007. For patients received the TPOG-AML-97A treatment, only 5-year OS rates were significantly different between patients diagnosed before and after 2008. Patients with RUNX1-RUNX1T1 had similar relapse-free survival rates, but 5-year OS rates were better during 2008-2019. However, the survival of patients who received hematopoietic stem-cell transplantations (HSCT) did not differ significantly before and after 2008. For patients without relapse, the 5-year OS improved during 2008-2019. Non-relapse mortality decreased annually, and cumulative relapse rates were similar. In conclusion, 5-year EFS and OS rates improved during 2008-2019, though intensities of chemotherapy treatments were similar before and after 2008. Non-relapse mortality decreased gradually. Further treatment strategies including more intensive chemotherapy, novel agents' use, identification of high-risk patients using genotyping and minimal residual disease, early intervention of HSCT, and antibiotic prophylaxis can be considered for future clinical protocol designs in Taiwan." @default.
W3136338571 created "2021-03-29" @default.
W3136338571 creator A5001569041 @default.
W3136338571 creator A5002873481 @default.
W3136338571 creator A5010668785 @default.
W3136338571 creator A5011004492 @default.
W3136338571 creator A5012801344 @default.
W3136338571 creator A5014261936 @default.
W3136338571 creator A5016674535 @default.
W3136338571 creator A5016979024 @default.
W3136338571 creator A5019453338 @default.
W3136338571 creator A5020715095 @default.
W3136338571 creator A5022590626 @default.
W3136338571 creator A5023112977 @default.
W3136338571 creator A5023856047 @default.
W3136338571 creator A5025928443 @default.
W3136338571 creator A5028791665 @default.
W3136338571 creator A5031791818 @default.
W3136338571 creator A5033553310 @default.
W3136338571 creator A5034882234 @default.
W3136338571 creator A5038466313 @default.
W3136338571 creator A5044868680 @default.
W3136338571 creator A5050252875 @default.
W3136338571 creator A5057937159 @default.
W3136338571 creator A5058085552 @default.
W3136338571 creator A5061680818 @default.
W3136338571 creator A5062560071 @default.
W3136338571 creator A5062637077 @default.
W3136338571 creator A5064779642 @default.
W3136338571 creator A5065341924 @default.
W3136338571 creator A5065572900 @default.
W3136338571 creator A5065759103 @default.
W3136338571 creator A5069347047 @default.
W3136338571 creator A5069929441 @default.
W3136338571 creator A5070994118 @default.
W3136338571 creator A5071772004 @default.
W3136338571 creator A5072158873 @default.
W3136338571 creator A5073763310 @default.
W3136338571 creator A5076962212 @default.
W3136338571 creator A5077923494 @default.
W3136338571 creator A5081155708 @default.
W3136338571 creator A5082986065 @default.
W3136338571 creator A5086609279 @default.
W3136338571 creator A5088638547 @default.
W3136338571 creator A5089325904 @default.
W3136338571 creator A5089837427 @default.
W3136338571 creator A5091524824 @default.
W3136338571 date "2021-03-15" @default.
W3136338571 modified "2023-10-11" @default.
W3136338571 title "Treatment outcomes of pediatric acute myeloid leukemia: a retrospective analysis from 1996 to 2019 in Taiwan" @default.
W3136338571 cites W1498271295 @default.
W3136338571 cites W1507489869 @default.
W3136338571 cites W1525555991 @default.
W3136338571 cites W1967150581 @default.
W3136338571 cites W1972953139 @default.
W3136338571 cites W1977985381 @default.
W3136338571 cites W1980100889 @default.
W3136338571 cites W1984614343 @default.
W3136338571 cites W2021982292 @default.
W3136338571 cites W2033039774 @default.
W3136338571 cites W2083165546 @default.
W3136338571 cites W2107968021 @default.
W3136338571 cites W2109703672 @default.
W3136338571 cites W2116440163 @default.
W3136338571 cites W2118250079 @default.
W3136338571 cites W2131713200 @default.
W3136338571 cites W2132693111 @default.
W3136338571 cites W2137423947 @default.
W3136338571 cites W2140929964 @default.
W3136338571 cites W2141869972 @default.
W3136338571 cites W2144341550 @default.
W3136338571 cites W2152182390 @default.
W3136338571 cites W2163358530 @default.
W3136338571 cites W2168891740 @default.
W3136338571 cites W2169923083 @default.
W3136338571 cites W2173804501 @default.
W3136338571 cites W2250451640 @default.
W3136338571 cites W2528975604 @default.
W3136338571 cites W2610889635 @default.
W3136338571 cites W2611952484 @default.
W3136338571 cites W2617342763 @default.
W3136338571 cites W2621998980 @default.
W3136338571 cites W2725729917 @default.
W3136338571 cites W2746557141 @default.
W3136338571 cites W2793614832 @default.
W3136338571 cites W2886678686 @default.
W3136338571 cites W2895050534 @default.
W3136338571 cites W2904637409 @default.
W3136338571 cites W2913703252 @default.
W3136338571 cites W2955461553 @default.
W3136338571 cites W2987507623 @default.
W3136338571 cites W2988966444 @default.
W3136338571 cites W2990654418 @default.
W3136338571 cites W2998127786 @default.
W3136338571 cites W3011638072 @default.
W3136338571 cites W3034704364 @default.
W3136338571 cites W4211166898 @default.
W3136338571 cites W4236468126 @default.
W3136338571 cites W4244077050 @default.
W3136338571 doi "https://doi.org/10.1038/s41598-021-85321-3" @default.