FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136349265> ?p ?o ?g. }

• W3136349265 endingPage "12" @default.
• W3136349265 startingPage "1" @default.
• W3136349265 abstract "Soft tissue sarcoma (STS) is a heterogeneous family of rare mesenchymal tumors, characterized by histopathological and molecular diversity. Tissue microarray (TMA) is a tool that allows performing research in orphan diseases in a more efficient and cost-effective way. TMAs are paraffin blocks consisting of multiple small representative tissue cores from biological samples, for example, from multiple donors, diverse sites of disease, or multiple different diseases. In 2015, we began constructing TMAs using archival tumor material from STS patients. Specimens were well annotated in terms of histopathological diagnosis, treatment, and clinical follow-up of the tissue donors. Each TMA block contains duplicate or triplicate 1.0–1.5 mm tissue cores from representative tumor areas selected by sarcoma pathologists. The construction of TMAs was performed with TMA Grand Master (3DHistech). So far, we have established disease-specific TMAs from 7 STS subtypes: gastrointestinal stromal tumor (72 cases included in the array), alveolar soft part sarcoma (n = 12 + 47), clear cell sarcoma (n = 22 + 32), leiomyosarcoma (n = 55), liposarcoma (n = 42), inflammatory myofibroblastic tumor (n = 12 + 21), and alveolar rhabdomyosarcoma (n = 24). We also constructed a multisarcoma TMA covering a representative number of important histopathological subtypes on arrays for screening purposes, namely, angiosarcoma, dedifferentiated liposarcoma, pleomorphic liposarcoma, and myxoid liposarcoma, leiomyosarcoma, malignant peripheral nerve sheath tumor, myxofibrosarcoma, rhabdomyosarcoma, synovial sarcoma, and undifferentiated pleomorphic sarcoma, with 7–11 individual cases per subtype. We are currently expanding the list of TMAs with additional sarcoma entities, considering the heterogeneity of this family of tumors. Our extensive STS TMA platform is suitable for rapid and cost-effective morphological, immunohistochemical, and molecular characterization of the tumor as well as for the identification of potential novel diagnostic markers and drug targets. It is readily available for collaborative projects with research partners." @default.
• W3136349265 created "2021-03-29" @default.
• W3136349265 creator A5018719411 @default.
• W3136349265 creator A5021550191 @default.
• W3136349265 creator A5041905625 @default.
• W3136349265 creator A5042786501 @default.
• W3136349265 creator A5042984084 @default.
• W3136349265 creator A5050142222 @default.
• W3136349265 creator A5055506828 @default.
• W3136349265 creator A5071512489 @default.
• W3136349265 creator A5073653373 @default.
• W3136349265 creator A5078295184 @default.
• W3136349265 creator A5083401778 @default.
• W3136349265 creator A5086102127 @default.
• W3136349265 date "2021-03-13" @default.
• W3136349265 modified "2023-10-14" @default.
• W3136349265 title "Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research" @default.
• W3136349265 cites W1200068469 @default.
• W3136349265 cites W1496992326 @default.
• W3136349265 cites W1969463489 @default.
• W3136349265 cites W1972170969 @default.
• W3136349265 cites W1986308239 @default.
• W3136349265 cites W1988669729 @default.
• W3136349265 cites W2029035352 @default.
• W3136349265 cites W2043730237 @default.
• W3136349265 cites W2060591619 @default.
• W3136349265 cites W2061179497 @default.
• W3136349265 cites W2063571129 @default.
• W3136349265 cites W2072661822 @default.
• W3136349265 cites W2087430412 @default.
• W3136349265 cites W2087810003 @default.
• W3136349265 cites W2109770623 @default.
• W3136349265 cites W2131505559 @default.
• W3136349265 cites W2135734390 @default.
• W3136349265 cites W2146355396 @default.
• W3136349265 cites W2154193486 @default.
• W3136349265 cites W2588118089 @default.
• W3136349265 cites W2603403798 @default.
• W3136349265 cites W2621958968 @default.
• W3136349265 cites W2755514319 @default.
• W3136349265 cites W2769616494 @default.
• W3136349265 cites W2773047103 @default.
• W3136349265 cites W2790254562 @default.
• W3136349265 cites W2793403013 @default.
• W3136349265 cites W2797695262 @default.
• W3136349265 cites W2800567296 @default.
• W3136349265 cites W2807534769 @default.
• W3136349265 cites W2883866956 @default.
• W3136349265 cites W2951721953 @default.
• W3136349265 cites W2951814896 @default.
• W3136349265 cites W2979724228 @default.
• W3136349265 cites W3015411213 @default.
• W3136349265 cites W3015807874 @default.
• W3136349265 cites W3037595396 @default.
• W3136349265 cites W3092409743 @default.
• W3136349265 cites W4213048107 @default.
• W3136349265 doi "https://doi.org/10.1155/2021/6675260" @default.
• W3136349265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8369337" @default.
• W3136349265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34413700" @default.
• W3136349265 hasPublicationYear "2021" @default.
• W3136349265 type Work @default.
• W3136349265 sameAs 3136349265 @default.
• W3136349265 citedByCount "4" @default.
• W3136349265 countsByYear W31363492652021 @default.
• W3136349265 countsByYear W31363492652022 @default.
• W3136349265 crossrefType "journal-article" @default.
• W3136349265 hasAuthorship W3136349265A5018719411 @default.
• W3136349265 hasAuthorship W3136349265A5021550191 @default.
• W3136349265 hasAuthorship W3136349265A5041905625 @default.
• W3136349265 hasAuthorship W3136349265A5042786501 @default.
• W3136349265 hasAuthorship W3136349265A5042984084 @default.
• W3136349265 hasAuthorship W3136349265A5050142222 @default.
• W3136349265 hasAuthorship W3136349265A5055506828 @default.
• W3136349265 hasAuthorship W3136349265A5071512489 @default.
• W3136349265 hasAuthorship W3136349265A5073653373 @default.
• W3136349265 hasAuthorship W3136349265A5078295184 @default.
• W3136349265 hasAuthorship W3136349265A5083401778 @default.
• W3136349265 hasAuthorship W3136349265A5086102127 @default.
• W3136349265 hasBestOaLocation W31363492651 @default.
• W3136349265 hasConcept C136948725 @default.
• W3136349265 hasConcept C142724271 @default.
• W3136349265 hasConcept C16930146 @default.
• W3136349265 hasConcept C193270364 @default.
• W3136349265 hasConcept C204232928 @default.
• W3136349265 hasConcept C2776522094 @default.
• W3136349265 hasConcept C2776910622 @default.
• W3136349265 hasConcept C2777007597 @default.
• W3136349265 hasConcept C2777532014 @default.
• W3136349265 hasConcept C2777666782 @default.
• W3136349265 hasConcept C2778173781 @default.
• W3136349265 hasConcept C2778256501 @default.
• W3136349265 hasConcept C2778464197 @default.
• W3136349265 hasConcept C2778629024 @default.
• W3136349265 hasConcept C2778758220 @default.
• W3136349265 hasConcept C2779052582 @default.
• W3136349265 hasConcept C2779568860 @default.
• W3136349265 hasConcept C2780844630 @default.
• W3136349265 hasConcept C2781225692 @default.

• next