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- W3136358722 abstract "This chapter describes the role of stem cells in the treatment of multidrug-resistant TB. Mesenchymal stem cells play an important immunomodulatory role in the pathogenesis of tuberculosis in patients that are affected by multidrug-resistant and extremely drug-resistant bacteria. Isolated from the host, autologous stem cells used in clinical trials have been shown to be safe and less toxic than current treatment regimens used against tuberculosis. Failed treatment regimens, poor patient compliance, and mutations by MTB have led to drug resistance, and these issues are also discussed. Several clinical trials have shown that stem cell therapy provides a safe alternative treatment that is better tolerated with fewer toxic side effects than current treatment regimens and will assist in slowing the global spread of TB. However, stem cell therapy is still in its early stages and much more intensive investigations are required to elucidate the role of stem cells in the treatment of drug-resistant TB." @default.
- W3136358722 created "2021-03-29" @default.
- W3136358722 creator A5081807210 @default.
- W3136358722 date "2021-01-01" @default.
- W3136358722 modified "2023-09-23" @default.
- W3136358722 title "Current approach of stem cell medicine in drug-resistant tuberculosis" @default.
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- W3136358722 doi "https://doi.org/10.1016/b978-0-12-819985-5.00001-2" @default.
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