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- W3136397714 abstract "Abstract A major function of the kidney is to, by glomerular filtration, maintain the overall steady‐state of 5–30 kDa proteins, many of which are signalling molecules. This function of the kidney has been overlooked, since predominantly low‐molecular‐mass substances <1 kDa have been used to measure or estimate glomerular filtration rate (GFR). The use of cystatin C (13 kDa) as a marker of GFR has allowed the discovery that the filtration of 5–30 kDa molecules can be selectively impaired defining the shrunken pore syndrome. The discovery, pathophysiology, morbidity (mainly cardiovascular manifestations) and mortality of this syndrome are described." @default.
- W3136397714 created "2021-03-29" @default.
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- W3136397714 date "2021-03-30" @default.
- W3136397714 modified "2023-10-16" @default.
- W3136397714 title "Glomerular filtration and shrunken pore syndrome in children and adults" @default.
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- W3136397714 doi "https://doi.org/10.1111/apa.15846" @default.
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