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- W3136452555 abstract "Breast cancer has the highest incidence rate of malignancy in women worldwide. A major clinical challenge faced by patients with breast cancer treated by conventional therapies is frequent relapse. This relapse has been attributed to the cancer stem cell (CSC) population that resides within the tumor and possess stemness properties. Breast CSCs are generated when breast cancer cells undergo epithelial-mesenchymal transition resulting in aggressive, highly metastatic, and invasive phenotypes that exhibit resistance towards chemotherapeutics. Metastasis, a phenomenon that aids in the migration of breast CSCs, occurs through any of three different routes: hematogenous, lymphatic, and transcoelomic. Hematogenous dissemination of breast CSCs leads to metastasis towards distant unrelated organs like lungs, liver, bone, and brain causing secondary tumor generation. Activation of metastasis genes or silencing of metastasis suppressor genes often leads to the advancement of metastasis. This review focuses on various genes and molecular factors that have been implicated to regulate organ-specific breast cancer metastasis by defying the available therapeutic interventions." @default.
- W3136452555 created "2021-03-29" @default.
- W3136452555 creator A5076993637 @default.
- W3136452555 creator A5085956532 @default.
- W3136452555 date "2021-12-01" @default.
- W3136452555 modified "2023-10-06" @default.
- W3136452555 title "Molecular mediators of breast cancer metastasis" @default.
- W3136452555 cites W104311660 @default.
- W3136452555 cites W1438161774 @default.
- W3136452555 cites W1480621946 @default.
- W3136452555 cites W1523079887 @default.
- W3136452555 cites W1596105818 @default.
- W3136452555 cites W1608726418 @default.
- W3136452555 cites W1809740262 @default.
- W3136452555 cites W1847015339 @default.
- W3136452555 cites W1880891411 @default.
- W3136452555 cites W1950118853 @default.
- W3136452555 cites W1964348356 @default.
- W3136452555 cites W1965371218 @default.
- W3136452555 cites W1966459698 @default.
- W3136452555 cites W1966578684 @default.
- W3136452555 cites W1968820371 @default.
- W3136452555 cites W1971343062 @default.
- W3136452555 cites W1973039656 @default.
- W3136452555 cites W1976033816 @default.
- W3136452555 cites W1983784090 @default.
- W3136452555 cites W1985023614 @default.
- W3136452555 cites W1993322072 @default.
- W3136452555 cites W1995209724 @default.
- W3136452555 cites W1997089955 @default.
- W3136452555 cites W2001286107 @default.
- W3136452555 cites W2001720727 @default.
- W3136452555 cites W2003730644 @default.
- W3136452555 cites W2006434892 @default.
- W3136452555 cites W2007196889 @default.
- W3136452555 cites W2008870230 @default.
- W3136452555 cites W2009014150 @default.
- W3136452555 cites W2009863423 @default.
- W3136452555 cites W2011960198 @default.
- W3136452555 cites W2012651591 @default.
- W3136452555 cites W2015182899 @default.
- W3136452555 cites W2015597738 @default.
- W3136452555 cites W2020158469 @default.
- W3136452555 cites W2023720844 @default.
- W3136452555 cites W2029548767 @default.
- W3136452555 cites W2029773366 @default.
- W3136452555 cites W2034855589 @default.
- W3136452555 cites W2039844465 @default.
- W3136452555 cites W2051940224 @default.
- W3136452555 cites W2052289997 @default.
- W3136452555 cites W2073158328 @default.
- W3136452555 cites W2075002120 @default.
- W3136452555 cites W2083232571 @default.
- W3136452555 cites W2083274861 @default.
- W3136452555 cites W2084987090 @default.
- W3136452555 cites W2088204809 @default.
- W3136452555 cites W2088556438 @default.
- W3136452555 cites W2090590858 @default.
- W3136452555 cites W2099261130 @default.
- W3136452555 cites W2105056222 @default.
- W3136452555 cites W2105183595 @default.
- W3136452555 cites W2109292973 @default.
- W3136452555 cites W2115189949 @default.
- W3136452555 cites W2116760308 @default.
- W3136452555 cites W2116975728 @default.
- W3136452555 cites W2120021814 @default.
- W3136452555 cites W2122909337 @default.
- W3136452555 cites W2125164793 @default.
- W3136452555 cites W2126584678 @default.
- W3136452555 cites W2126811493 @default.
- W3136452555 cites W2129211286 @default.
- W3136452555 cites W2131605616 @default.
- W3136452555 cites W2131994307 @default.
- W3136452555 cites W2133464443 @default.
- W3136452555 cites W2136546686 @default.
- W3136452555 cites W2138095640 @default.
- W3136452555 cites W2139030718 @default.
- W3136452555 cites W2146317640 @default.
- W3136452555 cites W2149914697 @default.
- W3136452555 cites W2151155898 @default.
- W3136452555 cites W2154568166 @default.
- W3136452555 cites W2155214429 @default.
- W3136452555 cites W2156323704 @default.
- W3136452555 cites W2156898371 @default.
- W3136452555 cites W2158287992 @default.
- W3136452555 cites W2160200374 @default.
- W3136452555 cites W2161092830 @default.
- W3136452555 cites W2163132378 @default.
- W3136452555 cites W2164394286 @default.
- W3136452555 cites W2165200432 @default.
- W3136452555 cites W2167105148 @default.
- W3136452555 cites W2168338978 @default.
- W3136452555 cites W2169334668 @default.
- W3136452555 cites W2169465106 @default.
- W3136452555 cites W2170304997 @default.
- W3136452555 cites W2280923709 @default.
- W3136452555 cites W2299095671 @default.
- W3136452555 cites W2313087390 @default.