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- W3136522110 abstract "Intranasal oxytocin (OT) has been suggested as a putative adjunctive treatment for patients with schizophrenia and autism spectrum disorders (ASD). Here, we examine available evidence from trials investigating the effects of repeated administrations of intranasal OT on the core symptoms of patients with schizophrenia and ASD, focusing on its therapeutic efficacy and heterogeneity of response (meta-ANOVA). Repeated administration of intranasal OT does not improve most of the core symptoms of schizophrenia and ASD, beyond a small tentative effect on schizophrenia general symptoms. However, we found significant moderator effects for dose in schizophrenia total psychopathology and positive symptoms, and percentage of included men and duration of treatment in schizophrenia general symptoms. We found evidence of heterogeneity (increased variance) in the response of schizophrenia negative symptoms to intranasal OT compared with placebo, suggesting that subgroups of responsive and non-responsive patients might coexist. For other core symptoms of schizophrenia, or any of the core symptom dimensions in ASD, the response to repeated treatment with intranasal OT did not show evidence of heterogeneity. LINKED ARTICLES: This article is part of a themed issue on Building Bridges in Neuropharmacology. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v179.8/issuetoc." @default.
- W3136522110 created "2021-03-29" @default.
- W3136522110 creator A5012070489 @default.
- W3136522110 creator A5025894040 @default.
- W3136522110 creator A5044072399 @default.
- W3136522110 date "2021-05-06" @default.
- W3136522110 modified "2023-10-18" @default.
- W3136522110 title "Heterogeneity in response to repeated intranasal oxytocin in schizophrenia and autism spectrum disorders: A meta‐analysis of variance" @default.
- W3136522110 cites W1591837399 @default.
- W3136522110 cites W1750764127 @default.
- W3136522110 cites W1823169087 @default.
- W3136522110 cites W1939311028 @default.
- W3136522110 cites W1966452992 @default.
- W3136522110 cites W1968228654 @default.
- W3136522110 cites W1970617251 @default.
- W3136522110 cites W1974375338 @default.
- W3136522110 cites W1975228824 @default.
- W3136522110 cites W1976654483 @default.
- W3136522110 cites W1978748770 @default.
- W3136522110 cites W2007872832 @default.
- W3136522110 cites W2009984993 @default.
- W3136522110 cites W2017323063 @default.
- W3136522110 cites W2026473386 @default.
- W3136522110 cites W2035561357 @default.
- W3136522110 cites W2038181972 @default.
- W3136522110 cites W2041684282 @default.
- W3136522110 cites W2042669554 @default.
- W3136522110 cites W2050566450 @default.
- W3136522110 cites W2062278675 @default.
- W3136522110 cites W2068471892 @default.
- W3136522110 cites W2070420735 @default.
- W3136522110 cites W2078390027 @default.
- W3136522110 cites W2081758073 @default.
- W3136522110 cites W2090207626 @default.
- W3136522110 cites W2092083729 @default.
- W3136522110 cites W2095898364 @default.
- W3136522110 cites W2097672669 @default.
- W3136522110 cites W2098923148 @default.
- W3136522110 cites W2099177143 @default.
- W3136522110 cites W2126398688 @default.
- W3136522110 cites W2129951232 @default.
- W3136522110 cites W2131925003 @default.
- W3136522110 cites W2134806674 @default.
- W3136522110 cites W2134902121 @default.
- W3136522110 cites W2140606211 @default.
- W3136522110 cites W2166079633 @default.
- W3136522110 cites W2166649563 @default.
- W3136522110 cites W2169219561 @default.
- W3136522110 cites W2173794558 @default.
- W3136522110 cites W2216419462 @default.
- W3136522110 cites W2224112374 @default.
- W3136522110 cites W2259158508 @default.
- W3136522110 cites W2272393891 @default.
- W3136522110 cites W2318201734 @default.
- W3136522110 cites W2399624761 @default.
- W3136522110 cites W2506824871 @default.
- W3136522110 cites W2514199772 @default.
- W3136522110 cites W2534481183 @default.
- W3136522110 cites W2558320693 @default.
- W3136522110 cites W2560374635 @default.
- W3136522110 cites W2560438049 @default.
- W3136522110 cites W2573197647 @default.
- W3136522110 cites W2577452335 @default.
- W3136522110 cites W2613162307 @default.
- W3136522110 cites W2613328034 @default.
- W3136522110 cites W2624006781 @default.
- W3136522110 cites W2735278545 @default.
- W3136522110 cites W2773566393 @default.
- W3136522110 cites W2809900380 @default.
- W3136522110 cites W2889420339 @default.
- W3136522110 cites W2900366804 @default.
- W3136522110 cites W2903331697 @default.
- W3136522110 cites W2903817743 @default.
- W3136522110 cites W2909165574 @default.
- W3136522110 cites W2915217457 @default.
- W3136522110 cites W2925087935 @default.
- W3136522110 cites W2940688781 @default.
- W3136522110 cites W2960208233 @default.
- W3136522110 cites W2963637818 @default.
- W3136522110 cites W2982236498 @default.
- W3136522110 cites W2987002164 @default.
- W3136522110 cites W2990915417 @default.
- W3136522110 cites W2996885413 @default.
- W3136522110 cites W3007261060 @default.
- W3136522110 cites W3009941151 @default.
- W3136522110 cites W3018825014 @default.
- W3136522110 cites W3026565435 @default.
- W3136522110 cites W3027892425 @default.
- W3136522110 cites W3031412498 @default.
- W3136522110 cites W3032430873 @default.
- W3136522110 cites W3049568087 @default.
- W3136522110 cites W3110433053 @default.
- W3136522110 cites W3120548380 @default.
- W3136522110 cites W4246287156 @default.
- W3136522110 cites W581256308 @default.
- W3136522110 doi "https://doi.org/10.1111/bph.15451" @default.
- W3136522110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33739447" @default.
- W3136522110 hasPublicationYear "2021" @default.