Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136607483> ?p ?o ?g. }
- W3136607483 endingPage "310" @default.
- W3136607483 startingPage "310" @default.
- W3136607483 abstract "Nanocrystalline materials (NCM, i.e., crystalline nanoparticles) have become an important class of materials with great potential for applications ranging from drug delivery and electronics to optics. Drug nanocrystals (NC) and nano co-crystals (NCC) are examples of NCM with fascinating physicochemical properties and have attracted significant attention in drug delivery. NCM are categorized by advantageous properties, such as high drug-loading efficiency, good long-term physical stability, steady and predictable drug release, and long systemic circulation time. These properties make them excellent formulations for the efficient delivery of a variety of active pharmaceutical ingredients (API). In this review, we summarize the recent advances in drug NCM-based therapy options. Currently, there are three main methods to synthesize drug NCM, including top-down, bottom-up, and combination methods. The fundamental characterization methods of drug NCM are elaborated. Furthermore, the applications of these characterizations and their implications on the post-formulation performance of NCM are introduced." @default.
- W3136607483 created "2021-03-29" @default.
- W3136607483 creator A5016891341 @default.
- W3136607483 creator A5021558260 @default.
- W3136607483 creator A5029219123 @default.
- W3136607483 creator A5072430912 @default.
- W3136607483 date "2021-03-21" @default.
- W3136607483 modified "2023-09-26" @default.
- W3136607483 title "Application of Fundamental Techniques for Physicochemical Characterizations to Understand Post-Formulation Performance of Pharmaceutical Nanocrystalline Materials" @default.
- W3136607483 cites W1194468842 @default.
- W3136607483 cites W126241540 @default.
- W3136607483 cites W1264540065 @default.
- W3136607483 cites W1491143151 @default.
- W3136607483 cites W1505631108 @default.
- W3136607483 cites W1576568858 @default.
- W3136607483 cites W1658687932 @default.
- W3136607483 cites W1846379412 @default.
- W3136607483 cites W1965364890 @default.
- W3136607483 cites W1966121878 @default.
- W3136607483 cites W1966355349 @default.
- W3136607483 cites W1966982589 @default.
- W3136607483 cites W1967870094 @default.
- W3136607483 cites W1968054977 @default.
- W3136607483 cites W1969644888 @default.
- W3136607483 cites W1970939924 @default.
- W3136607483 cites W1974149149 @default.
- W3136607483 cites W1974503306 @default.
- W3136607483 cites W1975828910 @default.
- W3136607483 cites W1976764164 @default.
- W3136607483 cites W1978137600 @default.
- W3136607483 cites W1979425595 @default.
- W3136607483 cites W1983162648 @default.
- W3136607483 cites W1987670851 @default.
- W3136607483 cites W1990424094 @default.
- W3136607483 cites W1990903461 @default.
- W3136607483 cites W1991916654 @default.
- W3136607483 cites W1993002471 @default.
- W3136607483 cites W1993066893 @default.
- W3136607483 cites W1995008519 @default.
- W3136607483 cites W1997764055 @default.
- W3136607483 cites W1998020561 @default.
- W3136607483 cites W1999098366 @default.
- W3136607483 cites W1999493153 @default.
- W3136607483 cites W2000924336 @default.
- W3136607483 cites W2001596955 @default.
- W3136607483 cites W2003093213 @default.
- W3136607483 cites W2006498847 @default.
- W3136607483 cites W2007068681 @default.
- W3136607483 cites W2009537932 @default.
- W3136607483 cites W2012384177 @default.
- W3136607483 cites W2012404925 @default.
- W3136607483 cites W2012867962 @default.
- W3136607483 cites W2015879870 @default.
- W3136607483 cites W2016895538 @default.
- W3136607483 cites W2016971948 @default.
- W3136607483 cites W2017702218 @default.
- W3136607483 cites W2017865089 @default.
- W3136607483 cites W2018032820 @default.
- W3136607483 cites W2021243298 @default.
- W3136607483 cites W2023328981 @default.
- W3136607483 cites W2023409962 @default.
- W3136607483 cites W2023616237 @default.
- W3136607483 cites W2024565434 @default.
- W3136607483 cites W2030319324 @default.
- W3136607483 cites W2031294959 @default.
- W3136607483 cites W2032842297 @default.
- W3136607483 cites W2036262674 @default.
- W3136607483 cites W2037464135 @default.
- W3136607483 cites W2038850098 @default.
- W3136607483 cites W2041317416 @default.
- W3136607483 cites W2041332307 @default.
- W3136607483 cites W2043504487 @default.
- W3136607483 cites W2046996525 @default.
- W3136607483 cites W2047549455 @default.
- W3136607483 cites W2049210214 @default.
- W3136607483 cites W2052681276 @default.
- W3136607483 cites W2056211275 @default.
- W3136607483 cites W2058307956 @default.
- W3136607483 cites W2058368669 @default.
- W3136607483 cites W2060298851 @default.
- W3136607483 cites W2060309057 @default.
- W3136607483 cites W2062619217 @default.
- W3136607483 cites W2063435985 @default.
- W3136607483 cites W2064802984 @default.
- W3136607483 cites W2067532006 @default.
- W3136607483 cites W2068524399 @default.
- W3136607483 cites W2070249775 @default.
- W3136607483 cites W2072225635 @default.
- W3136607483 cites W2077396556 @default.
- W3136607483 cites W2077888386 @default.
- W3136607483 cites W2080724281 @default.
- W3136607483 cites W2081445061 @default.
- W3136607483 cites W2083663613 @default.
- W3136607483 cites W2086929874 @default.
- W3136607483 cites W2087330633 @default.
- W3136607483 cites W2095564121 @default.
- W3136607483 cites W2096309345 @default.
- W3136607483 cites W2098329282 @default.