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- W3136677504 abstract "Oral complications may develop during the different phases of allogeneic hematopoietic cell transplantation (HCT). Xerostomia has been found to be indicative for salivary gland dysfunction in long-term HCT patients. Patients with xerostomia should receive meticulous oral hygiene, undertake preventive measures for dental and periodontal disease, and aggressive treatment of oral infections. The oral cavity is a common site for chronic graft-versus-host disease (cGVHD) with up to 80% of patients demonstrating involvement. Chronic oral graft-versus-host disease (GVHD) significantly increases the risk of developing a second malignancy in the oral cavity. Patients who are currently or have previously been treated with antiresorptive therapy such as bisphosphonates or denosumab are at risk for developing medication-related osteonecrosis of the jaws. The number of long-term HCT survivors is increasing, thus there is a need for monitoring late oral complications, such as persistent xerostomia, second malignancies, osteonecrosis of the jaw and sequelae of HCT including oral GVHD." @default.
- W3136677504 created "2021-03-29" @default.
- W3136677504 creator A5020002610 @default.
- W3136677504 date "2021-03-19" @default.
- W3136677504 modified "2023-09-23" @default.
- W3136677504 title "Management of oral and dental complications" @default.
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- W3136677504 doi "https://doi.org/10.1002/9781119612780.ch18" @default.
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