FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136752605> ?p ?o ?g. }

• W3136752605 endingPage "120464" @default.
• W3136752605 startingPage "120464" @default.
• W3136752605 abstract "During the last decade, an innovative lab on a chip technology known as microfluidics became popular in the pharmaceutical field to produce nanomedicines in a scalable way. Nevertheless, the predominant barriers for new microfluidics users are access to expensive equipment and device fabrication expertise. 3D printing technology promises to be an enabling new field that helps to overcome these drawbacks expanding the realm of microfluidics. Among 3D printing techniques, fused deposition modeling allows the production of devices with relatively inexpensive materials and printers. In this work, we developed two different microfluidic chips designed to obtain a passive micromixing by a “zigzag” bas-relief and by the presence of “split and recombine” channels. Computational fluid dynamics studies improved the evaluation of the mixing potential. A fused deposition modeling 3D printer was used to print the developed devices with polypropylene as manufacturing material. Then, two different model nanocarriers (i.e., polymeric nanoparticles and liposomes), loading cannabidiol as model drug, were formulated evaluating the influence of manufacturing parameters on the final nanocarrier characteristics with a design of experiments approach (2-level full factorial design). Both the chips showed an effective production of nanocarriers with tunable characteristics and with an efficient drug loading. These polypropylene-based microfluidic chips could represent an affordable and low-cost alternative to common microfluidic devices for the effective manufacturing of nanomedicines (both polymer- and lipid-based) after appropriate tuning of manufacturing parameters." @default.
• W3136752605 created "2021-03-29" @default.
• W3136752605 creator A5020542753 @default.
• W3136752605 creator A5025273458 @default.
• W3136752605 creator A5029998665 @default.
• W3136752605 creator A5032156889 @default.
• W3136752605 creator A5049071981 @default.
• W3136752605 creator A5073802845 @default.
• W3136752605 creator A5076642853 @default.
• W3136752605 date "2021-04-01" @default.
• W3136752605 modified "2023-10-14" @default.
• W3136752605 title "Microfluidics for nanomedicines manufacturing: An affordable and low-cost 3D printing approach" @default.
• W3136752605 cites W178041083 @default.
• W3136752605 cites W1977238598 @default.
• W3136752605 cites W2002825244 @default.
• W3136752605 cites W2003741425 @default.
• W3136752605 cites W2023248330 @default.
• W3136752605 cites W2047833469 @default.
• W3136752605 cites W2053550926 @default.
• W3136752605 cites W2060332933 @default.
• W3136752605 cites W2072422429 @default.
• W3136752605 cites W2085357851 @default.
• W3136752605 cites W2086939869 @default.
• W3136752605 cites W2110187357 @default.
• W3136752605 cites W2192893032 @default.
• W3136752605 cites W2323177876 @default.
• W3136752605 cites W2342593170 @default.
• W3136752605 cites W2575105131 @default.
• W3136752605 cites W2789728104 @default.
• W3136752605 cites W2883043629 @default.
• W3136752605 cites W2885477546 @default.
• W3136752605 cites W2955479136 @default.
• W3136752605 cites W2978489158 @default.
• W3136752605 cites W2979619560 @default.
• W3136752605 cites W3007262342 @default.
• W3136752605 cites W3009566311 @default.
• W3136752605 cites W3012174137 @default.
• W3136752605 cites W3013114744 @default.
• W3136752605 cites W3021575950 @default.
• W3136752605 cites W3042729956 @default.
• W3136752605 cites W3043200106 @default.
• W3136752605 cites W3092315280 @default.
• W3136752605 cites W4246059079 @default.
• W3136752605 cites W4301358551 @default.
• W3136752605 doi "https://doi.org/10.1016/j.ijpharm.2021.120464" @default.
• W3136752605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33713759" @default.
• W3136752605 hasPublicationYear "2021" @default.
• W3136752605 type Work @default.
• W3136752605 sameAs 3136752605 @default.
• W3136752605 citedByCount "28" @default.
• W3136752605 countsByYear W31367526052021 @default.
• W3136752605 countsByYear W31367526052022 @default.
• W3136752605 countsByYear W31367526052023 @default.
• W3136752605 crossrefType "journal-article" @default.
• W3136752605 hasAuthorship W3136752605A5020542753 @default.
• W3136752605 hasAuthorship W3136752605A5025273458 @default.
• W3136752605 hasAuthorship W3136752605A5029998665 @default.
• W3136752605 hasAuthorship W3136752605A5032156889 @default.
• W3136752605 hasAuthorship W3136752605A5049071981 @default.
• W3136752605 hasAuthorship W3136752605A5073802845 @default.
• W3136752605 hasAuthorship W3136752605A5076642853 @default.
• W3136752605 hasConcept C15083742 @default.
• W3136752605 hasConcept C155672457 @default.
• W3136752605 hasConcept C159985019 @default.
• W3136752605 hasConcept C171250308 @default.
• W3136752605 hasConcept C18150654 @default.
• W3136752605 hasConcept C192562407 @default.
• W3136752605 hasConcept C2779820397 @default.
• W3136752605 hasConcept C2780329122 @default.
• W3136752605 hasConcept C2780934452 @default.
• W3136752605 hasConcept C41008148 @default.
• W3136752605 hasConcept C524769229 @default.
• W3136752605 hasConcept C8673954 @default.
• W3136752605 hasConceptScore W3136752605C15083742 @default.
• W3136752605 hasConceptScore W3136752605C155672457 @default.
• W3136752605 hasConceptScore W3136752605C159985019 @default.
• W3136752605 hasConceptScore W3136752605C171250308 @default.
• W3136752605 hasConceptScore W3136752605C18150654 @default.
• W3136752605 hasConceptScore W3136752605C192562407 @default.
• W3136752605 hasConceptScore W3136752605C2779820397 @default.
• W3136752605 hasConceptScore W3136752605C2780329122 @default.
• W3136752605 hasConceptScore W3136752605C2780934452 @default.
• W3136752605 hasConceptScore W3136752605C41008148 @default.
• W3136752605 hasConceptScore W3136752605C524769229 @default.
• W3136752605 hasConceptScore W3136752605C8673954 @default.
• W3136752605 hasLocation W31367526051 @default.
• W3136752605 hasOpenAccess W3136752605 @default.
• W3136752605 hasPrimaryLocation W31367526051 @default.
• W3136752605 hasRelatedWork W2762204558 @default.
• W3136752605 hasRelatedWork W2903231397 @default.
• W3136752605 hasRelatedWork W2962612507 @default.
• W3136752605 hasRelatedWork W2995977988 @default.
• W3136752605 hasRelatedWork W3127609762 @default.
• W3136752605 hasRelatedWork W3138289793 @default.
• W3136752605 hasRelatedWork W3213203579 @default.
• W3136752605 hasRelatedWork W4360971178 @default.
• W3136752605 hasRelatedWork W4379987333 @default.
• W3136752605 hasRelatedWork W2803995364 @default.

• next