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- W313684671 abstract "Methane producing organisms are of interest because they provide an efficient and cost-effective biofuel that can be distributed readily using existing infrastructure. Methanosarcina acetivorans (MA) is a methanogenic archaeon found in diverse anaerobic habitats including oil wells, trash dumps, deep sea hydrothermal vents, and oxygen depleted sediments beneath kelp beds. With the largest genome of all known methanogenic archaea containing 4721 predicted genes; MA is considered to be the most metabolically diverse methanogenic archaea.As with other organisms, accurate gene functional annotation of methanogens lags significantly behind the large body of sequence data, representing a sizable gap in understanding of the biology of these organisms. One particular poorly understood system in MA is the biotin network, where homology based gene annotations show an incomplete biotin biosynthetic pathway. In an effort to better understand the biotin network in MA, we are studying the metabolomic differences of MA grown under biotin containing and biotin depleted conditions.We are using high mass resolution capability that FT-ICR mass spectrometry provides to investigate the changes in metabolism. Preliminary data indicates that ether lipids play major role in this archaea metabolism." @default.
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- W313684671 date "2012-01-01" @default.
- W313684671 modified "2023-09-25" @default.
- W313684671 title "Metabolite Profiling of Methanosarcina Acetivorans (MA) with Direct Infusion to FT-ICR" @default.
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