FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136860845> ?p ?o ?g. }

• W3136860845 abstract "Low and high egg producing hens exhibit gene expression differences related to ovarian steroidogenesis. High egg producing hens display increased expression of genes involved in progesterone and estradiol production, in the granulosa layer of the largest follicle (F1G) and small white follicles (SWF), respectively, whereas low egg producing hens display increased expression of genes related to progesterone and androgen production in the granulosa (F5G) and theca interna layer (F5I) of the fifth largest follicle, respectively. Transcriptome analysis was performed on F1G, F5G, F5I, and SWF samples from low and high egg producing hens to identify novel regulators of ovarian steroidogenesis. In total, 12,221 differentially expressed genes (DEGs) were identified between low and high egg producing hens across the four cell types examined. Pathway analysis implied differential regulation of the hypothalamo-pituitary-thyroid (HPT) axis, particularly thyroid hormone transporters and thyroid hormone receptors, and of estradiol signaling in low and high egg producing hens. The HPT axis showed up-regulation in high egg producing hens in less mature follicles but up-regulation in low egg producing hens in more mature follicles. Estradiol signaling exclusively exhibited up-regulation in high egg producing hens. Treatment of SWF cells from low and high egg producing hens with thyroid hormone in vitro decreased estradiol production in cells from high egg producing hens to the levels seen in cells from low egg producing hens, whereas thyroid hormone treatment did not impact estradiol production in cells from low egg producing hens. Transcriptome analysis of the major cell types involved in steroidogenesis inferred the involvement of the HPT axis and estradiol signaling in the regulation of differential steroid hormone production seen among hens with different egg production levels." @default.
• W3136860845 created "2021-03-29" @default.
• W3136860845 creator A5020661494 @default.
• W3136860845 creator A5030552895 @default.
• W3136860845 creator A5034265370 @default.
• W3136860845 creator A5042429684 @default.
• W3136860845 creator A5068422791 @default.
• W3136860845 date "2021-03-18" @default.
• W3136860845 modified "2023-09-27" @default.
• W3136860845 title "Transcriptome Analysis During Follicle Development in Turkey Hens With Low and High Egg Production" @default.
• W3136860845 cites W1274984702 @default.
• W3136860845 cites W1903013422 @default.
• W3136860845 cites W1972455454 @default.
• W3136860845 cites W1979635470 @default.
• W3136860845 cites W1982678390 @default.
• W3136860845 cites W1988009234 @default.
• W3136860845 cites W2003975080 @default.
• W3136860845 cites W2013764309 @default.
• W3136860845 cites W2030055950 @default.
• W3136860845 cites W2035016453 @default.
• W3136860845 cites W2036204980 @default.
• W3136860845 cites W2037098597 @default.
• W3136860845 cites W2039430966 @default.
• W3136860845 cites W2041266100 @default.
• W3136860845 cites W2051895244 @default.
• W3136860845 cites W2060093367 @default.
• W3136860845 cites W2064241974 @default.
• W3136860845 cites W2073325756 @default.
• W3136860845 cites W2098260977 @default.
• W3136860845 cites W2107870537 @default.
• W3136860845 cites W2109347638 @default.
• W3136860845 cites W2111150220 @default.
• W3136860845 cites W2113705043 @default.
• W3136860845 cites W2117546403 @default.
• W3136860845 cites W2119607161 @default.
• W3136860845 cites W2136609880 @default.
• W3136860845 cites W2142613067 @default.
• W3136860845 cites W2147196233 @default.
• W3136860845 cites W2162143298 @default.
• W3136860845 cites W2171630591 @default.
• W3136860845 cites W2261189741 @default.
• W3136860845 cites W2481902373 @default.
• W3136860845 cites W2594227676 @default.
• W3136860845 cites W2606277229 @default.
• W3136860845 cites W2760897315 @default.
• W3136860845 cites W2792550193 @default.
• W3136860845 cites W2969017928 @default.
• W3136860845 cites W3001364055 @default.
• W3136860845 cites W3081793010 @default.
• W3136860845 doi "https://doi.org/10.3389/fgene.2021.619196" @default.
• W3136860845 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8012691" @default.
• W3136860845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33815464" @default.
• W3136860845 hasPublicationYear "2021" @default.
• W3136860845 type Work @default.
• W3136860845 sameAs 3136860845 @default.
• W3136860845 citedByCount "8" @default.
• W3136860845 countsByYear W31368608452021 @default.
• W3136860845 countsByYear W31368608452022 @default.
• W3136860845 countsByYear W31368608452023 @default.
• W3136860845 crossrefType "journal-article" @default.
• W3136860845 hasAuthorship W3136860845A5020661494 @default.
• W3136860845 hasAuthorship W3136860845A5030552895 @default.
• W3136860845 hasAuthorship W3136860845A5034265370 @default.
• W3136860845 hasAuthorship W3136860845A5042429684 @default.
• W3136860845 hasAuthorship W3136860845A5068422791 @default.
• W3136860845 hasBestOaLocation W31368608451 @default.
• W3136860845 hasConcept C102570824 @default.
• W3136860845 hasConcept C104317684 @default.
• W3136860845 hasConcept C126322002 @default.
• W3136860845 hasConcept C134018914 @default.
• W3136860845 hasConcept C150194340 @default.
• W3136860845 hasConcept C162317418 @default.
• W3136860845 hasConcept C16685009 @default.
• W3136860845 hasConcept C175805485 @default.
• W3136860845 hasConcept C187785154 @default.
• W3136860845 hasConcept C2778324911 @default.
• W3136860845 hasConcept C2780536345 @default.
• W3136860845 hasConcept C526584372 @default.
• W3136860845 hasConcept C55493867 @default.
• W3136860845 hasConcept C71315377 @default.
• W3136860845 hasConcept C71924100 @default.
• W3136860845 hasConcept C86803240 @default.
• W3136860845 hasConceptScore W3136860845C102570824 @default.
• W3136860845 hasConceptScore W3136860845C104317684 @default.
• W3136860845 hasConceptScore W3136860845C126322002 @default.
• W3136860845 hasConceptScore W3136860845C134018914 @default.
• W3136860845 hasConceptScore W3136860845C150194340 @default.
• W3136860845 hasConceptScore W3136860845C162317418 @default.
• W3136860845 hasConceptScore W3136860845C16685009 @default.
• W3136860845 hasConceptScore W3136860845C175805485 @default.
• W3136860845 hasConceptScore W3136860845C187785154 @default.
• W3136860845 hasConceptScore W3136860845C2778324911 @default.
• W3136860845 hasConceptScore W3136860845C2780536345 @default.
• W3136860845 hasConceptScore W3136860845C526584372 @default.
• W3136860845 hasConceptScore W3136860845C55493867 @default.
• W3136860845 hasConceptScore W3136860845C71315377 @default.
• W3136860845 hasConceptScore W3136860845C71924100 @default.
• W3136860845 hasConceptScore W3136860845C86803240 @default.
• W3136860845 hasFunder F4320332299 @default.
• W3136860845 hasLocation W31368608451 @default.

• next