Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136928143> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3136928143 abstract "Flap endonuclease 1 (FEN1) is a multifunctional DNA branching nuclease. Post-translational modifications (PTMs) exist in this protein widely, including phosphorylation, methylation, acetylation, ubiquitination and small ubiquitination modification (SUMO). Here, we make a summary for those PTMs studies on FEN1, to illustrate relationships between mutations of those amino acids and their functions alteration of FEN1. Numerous evidences have confirmed that dysfunction of FEN1 would lead to genome instability, and then induce a variety of chromosome-related diseases ultimately, including tumors. On one hand, interaction partner also stimulates FEN1 nuclease activity, to further ensure an effective role in the processing of different DNA structures; on the other hand, PTMs may regulate protein-protein interactions and FEN1’s cellular localization." @default.
- W3136928143 created "2021-03-29" @default.
- W3136928143 creator A5011415259 @default.
- W3136928143 creator A5028064159 @default.
- W3136928143 creator A5037743899 @default.
- W3136928143 creator A5069818203 @default.
- W3136928143 date "2021-06-30" @default.
- W3136928143 modified "2023-09-23" @default.
- W3136928143 title "The Function of FEN1 is Regulated by Post-Translational Modification" @default.
- W3136928143 cites W1774053018 @default.
- W3136928143 cites W1832030339 @default.
- W3136928143 cites W1979275431 @default.
- W3136928143 cites W1980485757 @default.
- W3136928143 cites W2000945872 @default.
- W3136928143 cites W2001341780 @default.
- W3136928143 cites W2008233500 @default.
- W3136928143 cites W2008744347 @default.
- W3136928143 cites W2008758356 @default.
- W3136928143 cites W2013108773 @default.
- W3136928143 cites W2015122435 @default.
- W3136928143 cites W2015997780 @default.
- W3136928143 cites W2022690300 @default.
- W3136928143 cites W2023972288 @default.
- W3136928143 cites W2040135708 @default.
- W3136928143 cites W2053213954 @default.
- W3136928143 cites W2054877486 @default.
- W3136928143 cites W2064921878 @default.
- W3136928143 cites W2079708844 @default.
- W3136928143 cites W2087998931 @default.
- W3136928143 cites W2092265639 @default.
- W3136928143 cites W2114836779 @default.
- W3136928143 cites W2115638153 @default.
- W3136928143 cites W2121046220 @default.
- W3136928143 cites W2121781216 @default.
- W3136928143 cites W2123558100 @default.
- W3136928143 cites W2144805565 @default.
- W3136928143 cites W2147899637 @default.
- W3136928143 cites W2150123812 @default.
- W3136928143 cites W2153912626 @default.
- W3136928143 cites W2169553212 @default.
- W3136928143 cites W2314797738 @default.
- W3136928143 cites W2620071155 @default.
- W3136928143 cites W2890253927 @default.
- W3136928143 cites W2995017040 @default.
- W3136928143 doi "https://doi.org/10.5772/intechopen.96635" @default.
- W3136928143 hasPublicationYear "2021" @default.
- W3136928143 type Work @default.
- W3136928143 sameAs 3136928143 @default.
- W3136928143 citedByCount "0" @default.
- W3136928143 crossrefType "book-chapter" @default.
- W3136928143 hasAuthorship W3136928143A5011415259 @default.
- W3136928143 hasAuthorship W3136928143A5028064159 @default.
- W3136928143 hasAuthorship W3136928143A5037743899 @default.
- W3136928143 hasAuthorship W3136928143A5069818203 @default.
- W3136928143 hasBestOaLocation W31369281431 @default.
- W3136928143 hasConcept C104317684 @default.
- W3136928143 hasConcept C119157956 @default.
- W3136928143 hasConcept C185592680 @default.
- W3136928143 hasConcept C25602115 @default.
- W3136928143 hasConcept C2777028655 @default.
- W3136928143 hasConcept C2777271071 @default.
- W3136928143 hasConcept C552990157 @default.
- W3136928143 hasConcept C55493867 @default.
- W3136928143 hasConcept C86803240 @default.
- W3136928143 hasConcept C95444343 @default.
- W3136928143 hasConceptScore W3136928143C104317684 @default.
- W3136928143 hasConceptScore W3136928143C119157956 @default.
- W3136928143 hasConceptScore W3136928143C185592680 @default.
- W3136928143 hasConceptScore W3136928143C25602115 @default.
- W3136928143 hasConceptScore W3136928143C2777028655 @default.
- W3136928143 hasConceptScore W3136928143C2777271071 @default.
- W3136928143 hasConceptScore W3136928143C552990157 @default.
- W3136928143 hasConceptScore W3136928143C55493867 @default.
- W3136928143 hasConceptScore W3136928143C86803240 @default.
- W3136928143 hasConceptScore W3136928143C95444343 @default.
- W3136928143 hasLocation W31369281431 @default.
- W3136928143 hasOpenAccess W3136928143 @default.
- W3136928143 hasPrimaryLocation W31369281431 @default.
- W3136928143 hasRelatedWork W11818587 @default.
- W3136928143 hasRelatedWork W14170749 @default.
- W3136928143 hasRelatedWork W15954634 @default.
- W3136928143 hasRelatedWork W16081248 @default.
- W3136928143 hasRelatedWork W16193563 @default.
- W3136928143 hasRelatedWork W16279686 @default.
- W3136928143 hasRelatedWork W16776261 @default.
- W3136928143 hasRelatedWork W18472363 @default.
- W3136928143 hasRelatedWork W2158600 @default.
- W3136928143 hasRelatedWork W2784838 @default.
- W3136928143 isParatext "false" @default.
- W3136928143 isRetracted "false" @default.
- W3136928143 magId "3136928143" @default.
- W3136928143 workType "book-chapter" @default.