FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136998901> ?p ?o ?g. }

• W3136998901 abstract "Abstract Purpose : There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African women. Methods : We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for the association of lipid biomarkers – total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides – with odds of BC overall and by subtype (Luminal A, Luminal B, HER2-enriched and triple-negative or TNBC) for 296 newly diagnosed BC cases and 116 healthy controls in Nigeria. Results : Cases were slightly older than controls (48.5 vs. 46.0) and had a lower BMI (25.4 vs. 26.5). Each unit SD increase in triglycerides was associated with 39% increased odds of BC in fully adjusted models (aOR: 1.39; 95% CI: 1.03, 1.86). However, there were no significant associations of total cholesterol, LDL and HDL with odds of breast cancer in fully adjusted models. In analysis of molecular subtypes, each unit SD increase in LDL was associated with 64% increased odds of Luminal B BC (aOR 1.64; 95% CI: 1.06, 2.55). Each unit SD decrease in HDL was associated with 49% increased odds of TNBC (aOR: 1.49, 95% CI: 0.94, 2.34), and clinically low HDL was associated with 2.7 times increased odds of TNBC (aOR 2.67; 95% CI: 1.10, 6.49). Conclusions : Low HDL and high LDL appear to significantly increase the odds of TN and Luminal B BC, among African women. Future prospective studies can characterize this association and inform clinical approaches targeting HDL as a BC prevention strategy." @default.
• W3136998901 created "2021-03-29" @default.
• W3136998901 creator A5000910706 @default.
• W3136998901 creator A5005841132 @default.
• W3136998901 creator A5006213707 @default.
• W3136998901 creator A5006727990 @default.
• W3136998901 creator A5009876542 @default.
• W3136998901 creator A5014100248 @default.
• W3136998901 creator A5015053533 @default.
• W3136998901 creator A5015423998 @default.
• W3136998901 creator A5023341100 @default.
• W3136998901 creator A5026873580 @default.
• W3136998901 creator A5028180915 @default.
• W3136998901 creator A5031091122 @default.
• W3136998901 creator A5031659516 @default.
• W3136998901 creator A5032614083 @default.
• W3136998901 creator A5034046758 @default.
• W3136998901 creator A5038959604 @default.
• W3136998901 creator A5047070039 @default.
• W3136998901 creator A5056879131 @default.
• W3136998901 creator A5062992566 @default.
• W3136998901 creator A5064567400 @default.
• W3136998901 creator A5065205070 @default.
• W3136998901 creator A5074539440 @default.
• W3136998901 creator A5084514560 @default.
• W3136998901 creator A5088918635 @default.
• W3136998901 date "2021-03-10" @default.
• W3136998901 modified "2023-10-03" @default.
• W3136998901 title "Association of Lipid Profile Biomarkers with Breast Cancer by Molecular Subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Women of African Descent (MEND) study" @default.
• W3136998901 doi "https://doi.org/10.21203/rs.3.rs-271970/v1" @default.
• W3136998901 hasPublicationYear "2021" @default.
• W3136998901 type Work @default.
• W3136998901 sameAs 3136998901 @default.
• W3136998901 citedByCount "0" @default.
• W3136998901 crossrefType "posted-content" @default.
• W3136998901 hasAuthorship W3136998901A5000910706 @default.
• W3136998901 hasAuthorship W3136998901A5005841132 @default.
• W3136998901 hasAuthorship W3136998901A5006213707 @default.
• W3136998901 hasAuthorship W3136998901A5006727990 @default.
• W3136998901 hasAuthorship W3136998901A5009876542 @default.
• W3136998901 hasAuthorship W3136998901A5014100248 @default.
• W3136998901 hasAuthorship W3136998901A5015053533 @default.
• W3136998901 hasAuthorship W3136998901A5015423998 @default.
• W3136998901 hasAuthorship W3136998901A5023341100 @default.
• W3136998901 hasAuthorship W3136998901A5026873580 @default.
• W3136998901 hasAuthorship W3136998901A5028180915 @default.
• W3136998901 hasAuthorship W3136998901A5031091122 @default.
• W3136998901 hasAuthorship W3136998901A5031659516 @default.
• W3136998901 hasAuthorship W3136998901A5032614083 @default.
• W3136998901 hasAuthorship W3136998901A5034046758 @default.
• W3136998901 hasAuthorship W3136998901A5038959604 @default.
• W3136998901 hasAuthorship W3136998901A5047070039 @default.
• W3136998901 hasAuthorship W3136998901A5056879131 @default.
• W3136998901 hasAuthorship W3136998901A5062992566 @default.
• W3136998901 hasAuthorship W3136998901A5064567400 @default.
• W3136998901 hasAuthorship W3136998901A5065205070 @default.
• W3136998901 hasAuthorship W3136998901A5074539440 @default.
• W3136998901 hasAuthorship W3136998901A5084514560 @default.
• W3136998901 hasAuthorship W3136998901A5088918635 @default.
• W3136998901 hasBestOaLocation W31369989011 @default.
• W3136998901 hasConcept C121608353 @default.
• W3136998901 hasConcept C126322002 @default.
• W3136998901 hasConcept C134018914 @default.
• W3136998901 hasConcept C143095724 @default.
• W3136998901 hasConcept C143998085 @default.
• W3136998901 hasConcept C151956035 @default.
• W3136998901 hasConcept C156957248 @default.
• W3136998901 hasConcept C2780110267 @default.
• W3136998901 hasConcept C44249647 @default.
• W3136998901 hasConcept C530470458 @default.
• W3136998901 hasConcept C71924100 @default.
• W3136998901 hasConcept C90924648 @default.
• W3136998901 hasConceptScore W3136998901C121608353 @default.
• W3136998901 hasConceptScore W3136998901C126322002 @default.
• W3136998901 hasConceptScore W3136998901C134018914 @default.
• W3136998901 hasConceptScore W3136998901C143095724 @default.
• W3136998901 hasConceptScore W3136998901C143998085 @default.
• W3136998901 hasConceptScore W3136998901C151956035 @default.
• W3136998901 hasConceptScore W3136998901C156957248 @default.
• W3136998901 hasConceptScore W3136998901C2780110267 @default.
• W3136998901 hasConceptScore W3136998901C44249647 @default.
• W3136998901 hasConceptScore W3136998901C530470458 @default.
• W3136998901 hasConceptScore W3136998901C71924100 @default.
• W3136998901 hasConceptScore W3136998901C90924648 @default.
• W3136998901 hasLocation W31369989011 @default.
• W3136998901 hasOpenAccess W3136998901 @default.
• W3136998901 hasPrimaryLocation W31369989011 @default.
• W3136998901 hasRelatedWork W1966181922 @default.
• W3136998901 hasRelatedWork W1996753309 @default.
• W3136998901 hasRelatedWork W2006376692 @default.
• W3136998901 hasRelatedWork W2011313051 @default.
• W3136998901 hasRelatedWork W2037611947 @default.
• W3136998901 hasRelatedWork W2106414694 @default.
• W3136998901 hasRelatedWork W2156190299 @default.
• W3136998901 hasRelatedWork W2554176272 @default.
• W3136998901 hasRelatedWork W3162357257 @default.
• W3136998901 hasRelatedWork W4294578992 @default.
• W3136998901 isParatext "false" @default.
• W3136998901 isRetracted "false" @default.
• W3136998901 magId "3136998901" @default.

• next