Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137155283> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3137155283 abstract "Sleep-disordered breathing (SDB) in patients with motor neurone disease (MND) is normally attributed to hypoventilation due to muscle weakness. However, we have observed different patterns of SDB among MND patients referred for non-invasive ventilation, which do not appear to be explained by respiratory muscle weakness alone.The aim of this study was to examine the characteristics of SDB in MND.This is a retrospective analysis of sleep studies (using polysomnography [PSG]), pulmonary function tests, and arterial blood gases in MND patients referred to a tertiary sleep medicine service for clinical review. Sleep apnoeas were characterised as obstructive or central, and to further characterise the nature of SDB, hypopnoeas were classified as obstructive versus central.Among 13 MND patients who had a diagnostic PSG, the mean ± SD age was 68.9 ± 9.8 years, BMI 23.0 ± 4.3 kg/m2, forced vital capacity 55.7 ± 20.9% predicted, and partial pressure of CO2 (arterial blood) 52.7 ± 12.1 mm Hg. A total of 38% of patients (5/13) showed evidence of sleep hypoventilation. The total apnoea/hypopnoea index (AHI) was (median [interquartile range]) 44.4(36.2-56.4)/h, with 92% (12/13) showing an AHI >10/h, predominantly due to obstructive events, although 8% (1/13) also showed frequent central apnoea/hypopnoeas.Patients with MND exhibit a wide variety of SDB. The prevalence of obstructive sleep apnoea (OSA) is surprising considering the normal BMI in most patients. A dystonic tongue and increased upper-airway collapsibility might predispose these patients to OSA. The wide variety of SDB demonstrated might have implications for ventilator settings and patients' outcomes." @default.
- W3137155283 created "2021-03-29" @default.
- W3137155283 creator A5001755883 @default.
- W3137155283 creator A5001845698 @default.
- W3137155283 creator A5028231635 @default.
- W3137155283 creator A5037989848 @default.
- W3137155283 creator A5058046345 @default.
- W3137155283 creator A5069729518 @default.
- W3137155283 date "2020-01-01" @default.
- W3137155283 modified "2023-09-27" @default.
- W3137155283 title "Sleep-Disordered Breathing in Patients with Motor Neurone Disease: One Size Does Not Fit all" @default.
- W3137155283 cites W1550745673 @default.
- W3137155283 cites W1915092807 @default.
- W3137155283 cites W1990733926 @default.
- W3137155283 cites W1993090005 @default.
- W3137155283 cites W2010243063 @default.
- W3137155283 cites W2010934845 @default.
- W3137155283 cites W2039585404 @default.
- W3137155283 cites W2058263723 @default.
- W3137155283 cites W2074842950 @default.
- W3137155283 cites W2078469555 @default.
- W3137155283 cites W2107401597 @default.
- W3137155283 cites W2130427411 @default.
- W3137155283 cites W2130579636 @default.
- W3137155283 cites W2163655870 @default.
- W3137155283 cites W2341901271 @default.
- W3137155283 cites W2765900418 @default.
- W3137155283 cites W2901090747 @default.
- W3137155283 doi "https://doi.org/10.1159/000513887" @default.
- W3137155283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33735900" @default.
- W3137155283 hasPublicationYear "2020" @default.
- W3137155283 type Work @default.
- W3137155283 sameAs 3137155283 @default.
- W3137155283 citedByCount "1" @default.
- W3137155283 countsByYear W31371552832023 @default.
- W3137155283 crossrefType "journal-article" @default.
- W3137155283 hasAuthorship W3137155283A5001755883 @default.
- W3137155283 hasAuthorship W3137155283A5001845698 @default.
- W3137155283 hasAuthorship W3137155283A5028231635 @default.
- W3137155283 hasAuthorship W3137155283A5037989848 @default.
- W3137155283 hasAuthorship W3137155283A5058046345 @default.
- W3137155283 hasAuthorship W3137155283A5069729518 @default.
- W3137155283 hasConcept C119060515 @default.
- W3137155283 hasConcept C126322002 @default.
- W3137155283 hasConcept C127413603 @default.
- W3137155283 hasConcept C164705383 @default.
- W3137155283 hasConcept C200457457 @default.
- W3137155283 hasConcept C2778205975 @default.
- W3137155283 hasConcept C2778466831 @default.
- W3137155283 hasConcept C2779134260 @default.
- W3137155283 hasConcept C2779594553 @default.
- W3137155283 hasConcept C2780596555 @default.
- W3137155283 hasConcept C2781326671 @default.
- W3137155283 hasConcept C42219234 @default.
- W3137155283 hasConcept C534529494 @default.
- W3137155283 hasConcept C71924100 @default.
- W3137155283 hasConcept C78519656 @default.
- W3137155283 hasConceptScore W3137155283C119060515 @default.
- W3137155283 hasConceptScore W3137155283C126322002 @default.
- W3137155283 hasConceptScore W3137155283C127413603 @default.
- W3137155283 hasConceptScore W3137155283C164705383 @default.
- W3137155283 hasConceptScore W3137155283C200457457 @default.
- W3137155283 hasConceptScore W3137155283C2778205975 @default.
- W3137155283 hasConceptScore W3137155283C2778466831 @default.
- W3137155283 hasConceptScore W3137155283C2779134260 @default.
- W3137155283 hasConceptScore W3137155283C2779594553 @default.
- W3137155283 hasConceptScore W3137155283C2780596555 @default.
- W3137155283 hasConceptScore W3137155283C2781326671 @default.
- W3137155283 hasConceptScore W3137155283C42219234 @default.
- W3137155283 hasConceptScore W3137155283C534529494 @default.
- W3137155283 hasConceptScore W3137155283C71924100 @default.
- W3137155283 hasConceptScore W3137155283C78519656 @default.
- W3137155283 hasLocation W31371552831 @default.
- W3137155283 hasLocation W31371552832 @default.
- W3137155283 hasOpenAccess W3137155283 @default.
- W3137155283 hasPrimaryLocation W31371552831 @default.
- W3137155283 hasRelatedWork W11302680 @default.
- W3137155283 hasRelatedWork W13378054 @default.
- W3137155283 hasRelatedWork W14198678 @default.
- W3137155283 hasRelatedWork W1793858 @default.
- W3137155283 hasRelatedWork W19144914 @default.
- W3137155283 hasRelatedWork W1965689 @default.
- W3137155283 hasRelatedWork W4383305 @default.
- W3137155283 hasRelatedWork W4827426 @default.
- W3137155283 hasRelatedWork W5179739 @default.
- W3137155283 hasRelatedWork W6263835 @default.
- W3137155283 isParatext "false" @default.
- W3137155283 isRetracted "false" @default.
- W3137155283 magId "3137155283" @default.
- W3137155283 workType "article" @default.