Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137199685> ?p ?o ?g. }
- W3137199685 endingPage "83" @default.
- W3137199685 startingPage "76" @default.
- W3137199685 abstract "Neurons are long-lived cells with a complex architecture, in which synapses may be located far away from the cell body and are subject to plastic changes, thereby posing special challenges to the systems that maintain and dynamically regulate the synaptic proteome. These mechanisms include neuronal autophagy and the endolysosome pathway, as well as the ubiquitin/proteasome system, which cooperate in the constitutive and regulated turnover of presynaptic and postsynaptic proteins. Here, we summarize the pathways involved in synaptic protein degradation and the mechanisms underlying their regulation, for example, by neuronal activity, with an emphasis on the presynaptic compartment and outline perspectives for future research. Keywords: Synapse, Synaptic vesicle, Autophagy, Endolysosome, Proteasome, Protein turnover, Protein degradation, Endosome, Lysosome" @default.
- W3137199685 created "2021-03-29" @default.
- W3137199685 creator A5003163008 @default.
- W3137199685 creator A5013452452 @default.
- W3137199685 creator A5054087192 @default.
- W3137199685 date "2021-08-01" @default.
- W3137199685 modified "2023-10-16" @default.
- W3137199685 title "Mechanism of synaptic protein turnover and its regulation by neuronal activity" @default.
- W3137199685 cites W1985031488 @default.
- W3137199685 cites W1988178943 @default.
- W3137199685 cites W1992551226 @default.
- W3137199685 cites W2000874341 @default.
- W3137199685 cites W2006001960 @default.
- W3137199685 cites W2009966467 @default.
- W3137199685 cites W2038719756 @default.
- W3137199685 cites W2046585100 @default.
- W3137199685 cites W2053129791 @default.
- W3137199685 cites W2053818928 @default.
- W3137199685 cites W2074838566 @default.
- W3137199685 cites W2081631520 @default.
- W3137199685 cites W2118639179 @default.
- W3137199685 cites W2122791600 @default.
- W3137199685 cites W2126686784 @default.
- W3137199685 cites W2181193101 @default.
- W3137199685 cites W2508849304 @default.
- W3137199685 cites W2509350040 @default.
- W3137199685 cites W2527849633 @default.
- W3137199685 cites W2601351914 @default.
- W3137199685 cites W2792656249 @default.
- W3137199685 cites W2795560655 @default.
- W3137199685 cites W2801103925 @default.
- W3137199685 cites W2805844509 @default.
- W3137199685 cites W2806543441 @default.
- W3137199685 cites W2808848024 @default.
- W3137199685 cites W2810136351 @default.
- W3137199685 cites W2896466732 @default.
- W3137199685 cites W2901758236 @default.
- W3137199685 cites W2902404933 @default.
- W3137199685 cites W2907283267 @default.
- W3137199685 cites W2910722456 @default.
- W3137199685 cites W2914580150 @default.
- W3137199685 cites W2917398584 @default.
- W3137199685 cites W2938297872 @default.
- W3137199685 cites W2943109906 @default.
- W3137199685 cites W2954000601 @default.
- W3137199685 cites W2965965865 @default.
- W3137199685 cites W2974148748 @default.
- W3137199685 cites W2985101511 @default.
- W3137199685 cites W2988906435 @default.
- W3137199685 cites W2994628370 @default.
- W3137199685 cites W2994886188 @default.
- W3137199685 cites W2995824277 @default.
- W3137199685 cites W3008797387 @default.
- W3137199685 cites W3009452819 @default.
- W3137199685 cites W3010419162 @default.
- W3137199685 cites W3012498186 @default.
- W3137199685 cites W3014229249 @default.
- W3137199685 cites W3014984638 @default.
- W3137199685 cites W3022233430 @default.
- W3137199685 cites W3034595692 @default.
- W3137199685 cites W3048667246 @default.
- W3137199685 cites W3082069196 @default.
- W3137199685 cites W3094964773 @default.
- W3137199685 cites W3110893599 @default.
- W3137199685 cites W3116392218 @default.
- W3137199685 doi "https://doi.org/10.1016/j.conb.2021.02.006" @default.
- W3137199685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33744822" @default.
- W3137199685 hasPublicationYear "2021" @default.
- W3137199685 type Work @default.
- W3137199685 sameAs 3137199685 @default.
- W3137199685 citedByCount "16" @default.
- W3137199685 countsByYear W31371996852021 @default.
- W3137199685 countsByYear W31371996852022 @default.
- W3137199685 countsByYear W31371996852023 @default.
- W3137199685 crossrefType "journal-article" @default.
- W3137199685 hasAuthorship W3137199685A5003163008 @default.
- W3137199685 hasAuthorship W3137199685A5013452452 @default.
- W3137199685 hasAuthorship W3137199685A5054087192 @default.
- W3137199685 hasConcept C102747710 @default.
- W3137199685 hasConcept C104317684 @default.
- W3137199685 hasConcept C111472728 @default.
- W3137199685 hasConcept C127445978 @default.
- W3137199685 hasConcept C130316041 @default.
- W3137199685 hasConcept C138885662 @default.
- W3137199685 hasConcept C148785051 @default.
- W3137199685 hasConcept C169760540 @default.
- W3137199685 hasConcept C170493617 @default.
- W3137199685 hasConcept C181199279 @default.
- W3137199685 hasConcept C190283241 @default.
- W3137199685 hasConcept C195580219 @default.
- W3137199685 hasConcept C197341189 @default.
- W3137199685 hasConcept C203522944 @default.
- W3137199685 hasConcept C25602115 @default.
- W3137199685 hasConcept C27740335 @default.
- W3137199685 hasConcept C2780216420 @default.
- W3137199685 hasConcept C2992195973 @default.
- W3137199685 hasConcept C3675279 @default.
- W3137199685 hasConcept C41625074 @default.