Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137218982> ?p ?o ?g. }
- W3137218982 endingPage "609" @default.
- W3137218982 startingPage "601" @default.
- W3137218982 abstract "Patients with liver disease acquire complex changes in their hemostatic system. Historically, these patients were considered to have a bleeding tendency related, in part, to a hyperfibrinolytic state. However, studies using more modern fibrinolysis tests have questioned the presence of a hyperfibrinolytic state in patients with liver disease and its association with bleeding risk. It may be that the sickest patients with liver disease do have fibrinolytic abnormalities. However, the debate on the fibrinolytic state of patients with (decompensated) cirrhosis or critically ill liver disease is complicated by the fact that hypo- and hyperfibrinolysis have been poorly defined. This could, in part, be explained by the lack of reliable tests that assess a patient's fibrinolytic status. Moreover, large clinical studies on the relationship between bleeding and fibrinolysis in patients with liver disease are scarce. Here, we provide an overview of the current knowledge on fibrinolysis in various types of liver diseases and possible implications as a target for therapeutic strategies in liver disease. As antifibrinolytic therapy has been shown to be safe and effective during liver transplantation, it could potentially be of use in patients with (either laboratory-established or suspected) hyperfibrinolysis-related bleeding." @default.
- W3137218982 created "2021-03-29" @default.
- W3137218982 creator A5029344931 @default.
- W3137218982 creator A5074302578 @default.
- W3137218982 date "2021-03-26" @default.
- W3137218982 modified "2023-10-18" @default.
- W3137218982 title "Fibrinolysis in Patients with Liver Disease" @default.
- W3137218982 cites W1562275781 @default.
- W3137218982 cites W1769450009 @default.
- W3137218982 cites W1782727592 @default.
- W3137218982 cites W1934397638 @default.
- W3137218982 cites W1946750711 @default.
- W3137218982 cites W1981749711 @default.
- W3137218982 cites W1986837360 @default.
- W3137218982 cites W1993340951 @default.
- W3137218982 cites W1993575120 @default.
- W3137218982 cites W2018268831 @default.
- W3137218982 cites W2028816956 @default.
- W3137218982 cites W2034306276 @default.
- W3137218982 cites W2034413738 @default.
- W3137218982 cites W2043704659 @default.
- W3137218982 cites W2048027358 @default.
- W3137218982 cites W2056187496 @default.
- W3137218982 cites W2060836090 @default.
- W3137218982 cites W2063322610 @default.
- W3137218982 cites W2064567628 @default.
- W3137218982 cites W2065459298 @default.
- W3137218982 cites W2071449607 @default.
- W3137218982 cites W2075182040 @default.
- W3137218982 cites W2086252784 @default.
- W3137218982 cites W2087226513 @default.
- W3137218982 cites W2088383697 @default.
- W3137218982 cites W2090387429 @default.
- W3137218982 cites W2091463103 @default.
- W3137218982 cites W2091742879 @default.
- W3137218982 cites W2093338681 @default.
- W3137218982 cites W2094486696 @default.
- W3137218982 cites W2097708776 @default.
- W3137218982 cites W2100118997 @default.
- W3137218982 cites W210528726 @default.
- W3137218982 cites W2107522704 @default.
- W3137218982 cites W2117012107 @default.
- W3137218982 cites W2125581937 @default.
- W3137218982 cites W2128916601 @default.
- W3137218982 cites W2137010719 @default.
- W3137218982 cites W2144895900 @default.
- W3137218982 cites W2144919692 @default.
- W3137218982 cites W2145888792 @default.
- W3137218982 cites W2157280948 @default.
- W3137218982 cites W2160390803 @default.
- W3137218982 cites W2233281615 @default.
- W3137218982 cites W2344515048 @default.
- W3137218982 cites W2399199659 @default.
- W3137218982 cites W2413186508 @default.
- W3137218982 cites W2415488596 @default.
- W3137218982 cites W2488556807 @default.
- W3137218982 cites W2507044693 @default.
- W3137218982 cites W2607870311 @default.
- W3137218982 cites W2742683725 @default.
- W3137218982 cites W2744654376 @default.
- W3137218982 cites W2747912680 @default.
- W3137218982 cites W2760821898 @default.
- W3137218982 cites W2772388737 @default.
- W3137218982 cites W2786212616 @default.
- W3137218982 cites W2793000938 @default.
- W3137218982 cites W2796568037 @default.
- W3137218982 cites W2803891640 @default.
- W3137218982 cites W2809833128 @default.
- W3137218982 cites W2883884766 @default.
- W3137218982 cites W2909761474 @default.
- W3137218982 cites W2909810655 @default.
- W3137218982 cites W2968186435 @default.
- W3137218982 cites W2971304637 @default.
- W3137218982 cites W3021119552 @default.
- W3137218982 cites W3036528941 @default.
- W3137218982 cites W3190912488 @default.
- W3137218982 cites W4230071474 @default.
- W3137218982 cites W846039756 @default.
- W3137218982 doi "https://doi.org/10.1055/s-0040-1718924" @default.
- W3137218982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33772480" @default.
- W3137218982 hasPublicationYear "2021" @default.
- W3137218982 type Work @default.
- W3137218982 sameAs 3137218982 @default.
- W3137218982 citedByCount "9" @default.
- W3137218982 countsByYear W31372189822021 @default.
- W3137218982 countsByYear W31372189822022 @default.
- W3137218982 countsByYear W31372189822023 @default.
- W3137218982 crossrefType "journal-article" @default.
- W3137218982 hasAuthorship W3137218982A5029344931 @default.
- W3137218982 hasAuthorship W3137218982A5074302578 @default.
- W3137218982 hasBestOaLocation W31372189822 @default.
- W3137218982 hasConcept C126322002 @default.
- W3137218982 hasConcept C141071460 @default.
- W3137218982 hasConcept C177713679 @default.
- W3137218982 hasConcept C2776825266 @default.
- W3137218982 hasConcept C2777075537 @default.
- W3137218982 hasConcept C2777214474 @default.
- W3137218982 hasConcept C2779134260 @default.