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- W3137231642 endingPage "299" @default.
- W3137231642 startingPage "299" @default.
- W3137231642 abstract "The GATA family of transcription factors consists of six proteins (GATA1-6) that control a variety of physiological and pathological processes. In particular, GATA2 and GATA3 are coexpressed in a number of tissues, including in the urogenital and sympathoadrenal systems, in which both factors participate in the developmental process and tissue maintenance. Furthermore, accumulating studies have demonstrated that GATA2 and GATA3 are involved in distinct types of inherited diseases as well as carcinogenesis in diverse tissues. This review summarizes our current knowledge of how GATA2 and GATA3 participate in the transcriptional regulatory circuitry during the development of the sympathoadrenal and urogenital systems, and how their dysregulation results in the carcinogenesis of neuroblastoma, renal urothelial, and gynecologic cancers." @default.
- W3137231642 created "2021-03-29" @default.
- W3137231642 creator A5079658858 @default.
- W3137231642 date "2021-03-15" @default.
- W3137231642 modified "2023-09-24" @default.
- W3137231642 title "Development and Carcinogenesis: Roles of GATA Factors in the Sympathoadrenal and Urogenital Systems" @default.
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- W3137231642 doi "https://doi.org/10.3390/biomedicines9030299" @default.
- W3137231642 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8001475" @default.
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- W3137231642 hasPublicationYear "2021" @default.
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