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- W3137291257 endingPage "2093" @default.
- W3137291257 startingPage "2079" @default.
- W3137291257 abstract "Penicillium is a widely explored genus due to its chemical diversity and associated biological properties; in addition, it represents an important source for cytotoxic compounds with good application perspectives. Based on these aspects, in this review, Penicillium compounds that presented activity against human leukemia cell lines are being listed and discussed. For this, a careful bibliographic survey was carried out in the main electronic databases, i.e. Scopus, SciFinder, Web of Science and Pubmed. Between 1984 and 2020, thirty seven original papers were selected, when using the search terms Penicillium and leukemia. The occurrence of l-asparaginase produced by some Penicillium spp. was also highlighted since this enzyme is being employed for acute lymphoblastic leukemia and lymphosarcoma therapies. Therefore, this overview aims to demonstrate the potential of metabolites biosynthesized by Penicillium fungi which can be applied in human leukemia therapies and opportunities for designing new lead compounds." @default.
- W3137291257 created "2021-03-29" @default.
- W3137291257 creator A5011845598 @default.
- W3137291257 creator A5046400616 @default.
- W3137291257 creator A5050156485 @default.
- W3137291257 creator A5070696294 @default.
- W3137291257 creator A5072569877 @default.
- W3137291257 date "2021-03-18" @default.
- W3137291257 modified "2023-10-03" @default.
- W3137291257 title "<i>Penicillium</i> genus as a source for anti-leukemia compounds: an overview from 1984 to 2020" @default.
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