FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137331281> ?p ?o ?g. }

• W3137331281 endingPage "647025" @default.
• W3137331281 startingPage "647025" @default.
• W3137331281 abstract "Despite major advances in neonatal intensive care, infants born at extremely low birth weight still face an increased risk for chronic illness that may persist into adulthood. Pulmonary, retinal, and neurocognitive morbidities associated with preterm birth remain widespread despite interventions designed to minimize organ dysfunction. The design of therapeutic applications for preterm pathologies sharing common underlying triggers, such as fluctuations in oxygen supply or in the inflammatory state, requires alternative strategies that promote anti-inflammatory, pro-angiogenic, and trophic activities-ideally as a unitary treatment. Mesenchymal stem/stromal cell-derived extracellular vesicles (MEx) possess such inherent advantages, and they represent a most promising treatment candidate, as they have been shown to contribute to immunomodulation, homeostasis, and tissue regeneration. Current pre-clinical studies into the MEx mechanism of action are focusing on their restorative capability in the context of preterm birth-related pathologies, albeit not always with a multisystemic focus. This perspective will discuss the pathogenic mechanisms underlying the multisystemic lesions resulting from early-life disruption of normal physiology triggered by high oxygen exposures and pro-inflammatory conditions and introduce the application of MEx as immunomodulators and growth-promoting mediators for multisystem therapy." @default.
• W3137331281 created "2021-03-29" @default.
• W3137331281 creator A5000400855 @default.
• W3137331281 creator A5039732957 @default.
• W3137331281 creator A5051609710 @default.
• W3137331281 creator A5052675103 @default.
• W3137331281 creator A5056066296 @default.
• W3137331281 creator A5071192856 @default.
• W3137331281 creator A5074529580 @default.
• W3137331281 date "2021-01-01" @default.
• W3137331281 modified "2023-10-16" @default.
• W3137331281 title "Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective." @default.
• W3137331281 cites W1556848471 @default.
• W3137331281 cites W1857797615 @default.
• W3137331281 cites W1975478432 @default.
• W3137331281 cites W2006500041 @default.
• W3137331281 cites W2006618367 @default.
• W3137331281 cites W2027917639 @default.
• W3137331281 cites W2030814182 @default.
• W3137331281 cites W2033042544 @default.
• W3137331281 cites W2058579223 @default.
• W3137331281 cites W2071307510 @default.
• W3137331281 cites W2072806150 @default.
• W3137331281 cites W2082604867 @default.
• W3137331281 cites W2082896113 @default.
• W3137331281 cites W2089288497 @default.
• W3137331281 cites W2102520691 @default.
• W3137331281 cites W2114150640 @default.
• W3137331281 cites W2119809923 @default.
• W3137331281 cites W2128954340 @default.
• W3137331281 cites W2130576870 @default.
• W3137331281 cites W2131920995 @default.
• W3137331281 cites W2134014039 @default.
• W3137331281 cites W2138673644 @default.
• W3137331281 cites W2146894968 @default.
• W3137331281 cites W2207291742 @default.
• W3137331281 cites W2347148183 @default.
• W3137331281 cites W2397039719 @default.
• W3137331281 cites W2403570457 @default.
• W3137331281 cites W2534377661 @default.
• W3137331281 cites W2552379881 @default.
• W3137331281 cites W2564311069 @default.
• W3137331281 cites W2587852293 @default.
• W3137331281 cites W2592972178 @default.
• W3137331281 cites W2616451007 @default.
• W3137331281 cites W2617485792 @default.
• W3137331281 cites W2640481172 @default.
• W3137331281 cites W2752900046 @default.
• W3137331281 cites W2753884258 @default.
• W3137331281 cites W2763367588 @default.
• W3137331281 cites W2763485944 @default.
• W3137331281 cites W2769869753 @default.
• W3137331281 cites W2770711795 @default.
• W3137331281 cites W2798170384 @default.
• W3137331281 cites W2811208517 @default.
• W3137331281 cites W2885557301 @default.
• W3137331281 cites W2891258623 @default.
• W3137331281 cites W2900756811 @default.
• W3137331281 cites W2904254259 @default.
• W3137331281 cites W2925330721 @default.
• W3137331281 cites W2942732217 @default.
• W3137331281 cites W2977617462 @default.
• W3137331281 cites W2990915601 @default.
• W3137331281 cites W3007356512 @default.
• W3137331281 cites W3041361526 @default.
• W3137331281 cites W3042461304 @default.
• W3137331281 cites W2069177787 @default.
• W3137331281 doi "https://doi.org/10.3389/fcell.2021.647025" @default.
• W3137331281 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8007882" @default.
• W3137331281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33796534" @default.
• W3137331281 hasPublicationYear "2021" @default.
• W3137331281 type Work @default.
• W3137331281 sameAs 3137331281 @default.
• W3137331281 citedByCount "11" @default.
• W3137331281 countsByYear W31373312812021 @default.
• W3137331281 countsByYear W31373312812022 @default.
• W3137331281 countsByYear W31373312812023 @default.
• W3137331281 crossrefType "journal-article" @default.
• W3137331281 hasAuthorship W3137331281A5000400855 @default.
• W3137331281 hasAuthorship W3137331281A5039732957 @default.
• W3137331281 hasAuthorship W3137331281A5051609710 @default.
• W3137331281 hasAuthorship W3137331281A5052675103 @default.
• W3137331281 hasAuthorship W3137331281A5056066296 @default.
• W3137331281 hasAuthorship W3137331281A5071192856 @default.
• W3137331281 hasAuthorship W3137331281A5074529580 @default.
• W3137331281 hasBestOaLocation W31373312811 @default.
• W3137331281 hasConcept C126322002 @default.
• W3137331281 hasConcept C142724271 @default.
• W3137331281 hasConcept C151730666 @default.
• W3137331281 hasConcept C16930146 @default.
• W3137331281 hasConcept C169760540 @default.
• W3137331281 hasConcept C198826908 @default.
• W3137331281 hasConcept C203014093 @default.
• W3137331281 hasConcept C2776914184 @default.
• W3137331281 hasConcept C2777714996 @default.
• W3137331281 hasConcept C2778376644 @default.
• W3137331281 hasConcept C2778721537 @default.
• W3137331281 hasConcept C2779134260 @default.

• next