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- W3137331761 abstract "Sheep pox and goat pox are viral disease that are endemic in Middle East and cause significant economic loses. They caused by strains of Capripoxvirus. A few strains are equally pathogenic and immunogenic in both sheep and goat, although most cause more severe clinical disease and are immunogenic in only one species. Gorgan strain is a goat pox virus that has been used as goat pox vaccine since 1959 in Iran. In this study subcutaneous injection of 10 2.5, 103.5, 104.5, 105.5 TCID50 attenuated Gorgan goat pox vaccine was used for immunization sheep and compared with sheep pox vaccine. Titration of sheep pox 8316 wild strain in flank in or Intradermal injection of 104 RD50 was used for challenging. Challenge virus titre was 106.5, 105.8, 104.9, 105 respectively in groups that mentioned and it was 10 3.25 and 10 7 in sheep pox vaccinated and control respectively. Therefore, only sheep pox vaccinated had a difference of log titre log10 2.5 as evidence of protection in titration challenge. In challenging with intradermal injection of RD50, only sheep pox vaccinated was completely immune although the disease didn't generalize in any vaccinates and 65% vaccinated animal with high titre(10 4.5 ) were immune. It seems that Gorgan strain of goat pox can not induce an effective immunity against sheep pox in sheep." @default.
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- W3137331761 date "2008-01-01" @default.
- W3137331761 modified "2023-09-23" @default.
- W3137331761 title "Study of Safety and Immunogenicity of Goat Pox Vaccine against Sheep Pox in Susceptible Sheep." @default.
- W3137331761 hasPublicationYear "2008" @default.
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