FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137392705> ?p ?o ?g. }

• W3137392705 endingPage "100181" @default.
• W3137392705 startingPage "100181" @default.
• W3137392705 abstract "The translatome, a profile of the translational status of genetic information within cells, provides a new perspective on gene expression. Although many plant genomes have been sequenced, comprehensive translatomic annotations are not available for plants due to a lack of efficient translatome profiling techniques. Here, we developed a new technique termed 3′ ribosome-profiling sequencing (3′Ribo-seq) for reliable, robust translatomic profiling. 3′Ribo-seq combines polysome profiling and 3′ selection with a barcoding and pooling strategy. Systematic translatome profiling of different tissues of Arabidopsis, rice, and maize using conventional ribosome profiling (Ribo-seq) and 3′Ribo-seq revealed many novel translational genomic loci, thereby complementing functional genome annotation in plants. Using the low-cost, efficient 3′Ribo-seq technique and genome-wide association mapping of translatome expression (eGWAS), we performed a population-level dissection of the translatomes of 159 diverse maize inbred lines and identified 1,777 translational expression quantitative trait loci (eQTLs). Notably, local eQTLs are significantly enriched in the 3′ untranslated regions of genes. Detailed eQTL analysis suggested that sequence variation around the polyadenylation (polyA) signal motif plays a key role in translatomic variation. Our study provides a comprehensive translatome annotation of plant functional genomes and introduces 3′Ribo-seq, which paves the way for deep translatomic analysis at the population level." @default.
• W3137392705 created "2021-03-29" @default.
• W3137392705 creator A5002649440 @default.
• W3137392705 creator A5005573660 @default.
• W3137392705 creator A5007219244 @default.
• W3137392705 creator A5011121798 @default.
• W3137392705 creator A5039849475 @default.
• W3137392705 creator A5055493931 @default.
• W3137392705 creator A5059309879 @default.
• W3137392705 creator A5064255772 @default.
• W3137392705 creator A5069296078 @default.
• W3137392705 date "2021-07-01" @default.
• W3137392705 modified "2023-10-13" @default.
• W3137392705 title "Large-scale translatome profiling annotates the functional genome and reveals the key role of genic 3′ untranslated regions in translatomic variation in plants" @default.
• W3137392705 cites W1864021403 @default.
• W3137392705 cites W1906706885 @default.
• W3137392705 cites W1966275499 @default.
• W3137392705 cites W1968164444 @default.
• W3137392705 cites W1973268693 @default.
• W3137392705 cites W1986705163 @default.
• W3137392705 cites W1993210315 @default.
• W3137392705 cites W1993981485 @default.
• W3137392705 cites W1999574084 @default.
• W3137392705 cites W2008410413 @default.
• W3137392705 cites W2027980770 @default.
• W3137392705 cites W2030722598 @default.
• W3137392705 cites W2036581163 @default.
• W3137392705 cites W2041677964 @default.
• W3137392705 cites W2045124856 @default.
• W3137392705 cites W2054563332 @default.
• W3137392705 cites W2054574453 @default.
• W3137392705 cites W2079517684 @default.
• W3137392705 cites W2084942072 @default.
• W3137392705 cites W2088486634 @default.
• W3137392705 cites W2100305481 @default.
• W3137392705 cites W2102212449 @default.
• W3137392705 cites W2102278945 @default.
• W3137392705 cites W2104005232 @default.
• W3137392705 cites W2105879579 @default.
• W3137392705 cites W2108078395 @default.
• W3137392705 cites W2108264419 @default.
• W3137392705 cites W2118031210 @default.
• W3137392705 cites W2118834857 @default.
• W3137392705 cites W2119444539 @default.
• W3137392705 cites W2128551987 @default.
• W3137392705 cites W2133301154 @default.
• W3137392705 cites W2135937351 @default.
• W3137392705 cites W2138098955 @default.
• W3137392705 cites W2139838862 @default.
• W3137392705 cites W2142589193 @default.
• W3137392705 cites W2152532695 @default.
• W3137392705 cites W2154825888 @default.
• W3137392705 cites W2161030070 @default.
• W3137392705 cites W2162530578 @default.
• W3137392705 cites W2170551349 @default.
• W3137392705 cites W2170669858 @default.
• W3137392705 cites W2316200901 @default.
• W3137392705 cites W2342688693 @default.
• W3137392705 cites W2463761386 @default.
• W3137392705 cites W2515922456 @default.
• W3137392705 cites W2576961387 @default.
• W3137392705 cites W2623168030 @default.
• W3137392705 cites W2794298643 @default.
• W3137392705 cites W2804011390 @default.
• W3137392705 cites W2804476515 @default.
• W3137392705 cites W2887970906 @default.
• W3137392705 cites W2899630292 @default.
• W3137392705 cites W2908822468 @default.
• W3137392705 cites W2952109315 @default.
• W3137392705 cites W2971539337 @default.
• W3137392705 cites W3012068569 @default.
• W3137392705 cites W3028519422 @default.
• W3137392705 cites W3036319615 @default.
• W3137392705 cites W3092933521 @default.
• W3137392705 cites W3127626595 @default.
• W3137392705 cites W4251041305 @default.
• W3137392705 cites W4297168595 @default.
• W3137392705 doi "https://doi.org/10.1016/j.xplc.2021.100181" @default.
• W3137392705 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8299070" @default.
• W3137392705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34327320" @default.
• W3137392705 hasPublicationYear "2021" @default.
• W3137392705 type Work @default.
• W3137392705 sameAs 3137392705 @default.
• W3137392705 citedByCount "14" @default.
• W3137392705 countsByYear W31373927052021 @default.
• W3137392705 countsByYear W31373927052022 @default.
• W3137392705 countsByYear W31373927052023 @default.
• W3137392705 crossrefType "journal-article" @default.
• W3137392705 hasAuthorship W3137392705A5002649440 @default.
• W3137392705 hasAuthorship W3137392705A5005573660 @default.
• W3137392705 hasAuthorship W3137392705A5007219244 @default.
• W3137392705 hasAuthorship W3137392705A5011121798 @default.
• W3137392705 hasAuthorship W3137392705A5039849475 @default.
• W3137392705 hasAuthorship W3137392705A5055493931 @default.
• W3137392705 hasAuthorship W3137392705A5059309879 @default.
• W3137392705 hasAuthorship W3137392705A5064255772 @default.
• W3137392705 hasAuthorship W3137392705A5069296078 @default.
• W3137392705 hasBestOaLocation W31373927051 @default.

• next