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• W3137418175 abstract "Diabetes mellitus is characterized by a hyperglycemia, characterized by increased blood sugar level and glycosylated hemoglobin (HbA1c). Hyperglycemia also produced excessive amount of Reactive Oxygen Species (ROS) which caused increased level of serum Malondialdehyde (MDA) and progressive changes in the mean amount of the pancreatic islets. Matoa bark extract is used as an antidiabetic agent containing polyphenols and flavonoids which acts as antioxidants againts Reactive Oxygen Species (ROS) and also as an α-glucosidase enzyme inhibitors. To determine the antidiabetic effect of matoa stem bark extract on alloxan-induced Wistar rats. Experimental research design with post-test only control group design. The control group was positive, negative, and 4 treatment groups consisted of 5 experimental animals in each group for 38 days. Blood sugar and MDA are measured using a spectrophotometer. HbA1c was measured using the HPLC method. Langerhans Island was dyed HE checked using a microscope. Data were analyzed using ANOVA, Post Hoc, and Regression tests. ANOVA test results have a significant effect (p = 0,000). Post Hoc test results obtained a significant difference (p" @default.
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• W3137418175 date "2020-01-01" @default.
• W3137418175 modified "2023-09-23" @default.
• W3137418175 title "ANTIDIABETIC POTENTIAL OF MATOA BARK EXTRACT (Pometia pinnata) IN ALLOXAN-INDUCED DIABETIC MALE RAT STRAIN WISTAR (Rattus norvegicus)" @default.
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