FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137466538> ?p ?o ?g. }

• W3137466538 endingPage "2219" @default.
• W3137466538 startingPage "2210" @default.
• W3137466538 abstract "This study aimed to determine the effects of sodium-glucose cotransporter-2 inhibitor (SGLT2i) in heart failure with reduced ejection fraction (HFrEF), compare the effect of SGLT2i with angiotensin receptor neprilysin inhibitor (ARNI), and find whether combination of SGLT2i and ARNI is better than monotherapy.Embase, Medline, and Cochrane Central Registry of Controlled Trials were searched for randomized controlled trials evaluating SGLT2i or ARNI in HFrEF. And a total of six trials were included. SGLT2i was found to significantly reduce the risk of cardiovascular death or hospitalization for heart failure by 27% [hazard ratio (HR) 0.73, 95% confidence interval (CI) 0.67-0.80], hospitalization for heart failure by 31% (HR 0.69, 95% CI 0.62-0.77), cardiovascular death by 16% (HR 0.84, 95% CI 0.74-0.95), and all-cause death by 16% (HR 0.84, 95% CI 0.75-0.94) in HFrEF only with a statistically higher risk of genital infection (risk ratio (RR) 2.78, 95% CI 1.46-5.29). The reduction in cardiovascular death or hospitalization for heart failure was of similar magnitude in patients with or without diabetes mellitus (HR 0.71, 95% CI 0.64-0.80 vs. HR 0.75, 95% CI 0.65-0.87) using SGLT2i. Indirect treatment comparison showed that SGLT2i and ARNI had similar effects on primary outcome (HR 0.93, 95% CI 0.82-1.06). And combination of SGLT2i and ARNI achieved a better prognosis performance (HR 0.68, 95% CI 0.53-0.89) compared with ARNI monotherapy.SGLT2i could safely reduce cardiovascular death or hospitalization for heart failure in HFrEF regardless of diabetes mellitus status. SGLT2i and ARNI demonstrate similar effects, while combination of SGLT2i and ARNI results in a better cardiovascular protective effect." @default.
• W3137466538 created "2021-03-29" @default.
• W3137466538 creator A5008496072 @default.
• W3137466538 creator A5013881064 @default.
• W3137466538 creator A5037677450 @default.
• W3137466538 creator A5048682332 @default.
• W3137466538 creator A5048826252 @default.
• W3137466538 creator A5054294373 @default.
• W3137466538 creator A5054978768 @default.
• W3137466538 creator A5087695635 @default.
• W3137466538 creator A5088300347 @default.
• W3137466538 date "2021-03-21" @default.
• W3137466538 modified "2023-10-16" @default.
• W3137466538 title "SGLT2i versus ARNI in heart failure with reduced ejection fraction: a systematic review and meta‐analysis" @default.
• W3137466538 cites W2068171948 @default.
• W3137466538 cites W2113698123 @default.
• W3137466538 cites W2146264128 @default.
• W3137466538 cites W2289709123 @default.
• W3137466538 cites W2341611738 @default.
• W3137466538 cites W2427094903 @default.
• W3137466538 cites W2468095632 @default.
• W3137466538 cites W2473842483 @default.
• W3137466538 cites W2519669846 @default.
• W3137466538 cites W2557983041 @default.
• W3137466538 cites W2577614303 @default.
• W3137466538 cites W2609605008 @default.
• W3137466538 cites W2626446274 @default.
• W3137466538 cites W2784567604 @default.
• W3137466538 cites W2789606819 @default.
• W3137466538 cites W2900413769 @default.
• W3137466538 cites W2913564090 @default.
• W3137466538 cites W2914699275 @default.
• W3137466538 cites W2919368874 @default.
• W3137466538 cites W2921866736 @default.
• W3137466538 cites W2936593438 @default.
• W3137466538 cites W2938564873 @default.
• W3137466538 cites W2971294569 @default.
• W3137466538 cites W2974260792 @default.
• W3137466538 cites W2996517820 @default.
• W3137466538 cites W3015945217 @default.
• W3137466538 cites W3038036007 @default.
• W3137466538 cites W3081830235 @default.
• W3137466538 cites W3100542962 @default.
• W3137466538 cites W3137466538 @default.
• W3137466538 cites W4238907867 @default.
• W3137466538 doi "https://doi.org/10.1002/ehf2.13313" @default.
• W3137466538 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8120387" @default.
• W3137466538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33749159" @default.
• W3137466538 hasPublicationYear "2021" @default.
• W3137466538 type Work @default.
• W3137466538 sameAs 3137466538 @default.
• W3137466538 citedByCount "20" @default.
• W3137466538 countsByYear W31374665382021 @default.
• W3137466538 countsByYear W31374665382022 @default.
• W3137466538 countsByYear W31374665382023 @default.
• W3137466538 crossrefType "journal-article" @default.
• W3137466538 hasAuthorship W3137466538A5008496072 @default.
• W3137466538 hasAuthorship W3137466538A5013881064 @default.
• W3137466538 hasAuthorship W3137466538A5037677450 @default.
• W3137466538 hasAuthorship W3137466538A5048682332 @default.
• W3137466538 hasAuthorship W3137466538A5048826252 @default.
• W3137466538 hasAuthorship W3137466538A5054294373 @default.
• W3137466538 hasAuthorship W3137466538A5054978768 @default.
• W3137466538 hasAuthorship W3137466538A5087695635 @default.
• W3137466538 hasAuthorship W3137466538A5088300347 @default.
• W3137466538 hasBestOaLocation W31374665382 @default.
• W3137466538 hasConcept C126322002 @default.
• W3137466538 hasConcept C134018914 @default.
• W3137466538 hasConcept C164705383 @default.
• W3137466538 hasConcept C168563851 @default.
• W3137466538 hasConcept C207103383 @default.
• W3137466538 hasConcept C2778198053 @default.
• W3137466538 hasConcept C44249647 @default.
• W3137466538 hasConcept C555293320 @default.
• W3137466538 hasConcept C71924100 @default.
• W3137466538 hasConcept C78085059 @default.
• W3137466538 hasConcept C95190672 @default.
• W3137466538 hasConceptScore W3137466538C126322002 @default.
• W3137466538 hasConceptScore W3137466538C134018914 @default.
• W3137466538 hasConceptScore W3137466538C164705383 @default.
• W3137466538 hasConceptScore W3137466538C168563851 @default.
• W3137466538 hasConceptScore W3137466538C207103383 @default.
• W3137466538 hasConceptScore W3137466538C2778198053 @default.
• W3137466538 hasConceptScore W3137466538C44249647 @default.
• W3137466538 hasConceptScore W3137466538C555293320 @default.
• W3137466538 hasConceptScore W3137466538C71924100 @default.
• W3137466538 hasConceptScore W3137466538C78085059 @default.
• W3137466538 hasConceptScore W3137466538C95190672 @default.
• W3137466538 hasFunder F4320321001 @default.
• W3137466538 hasFunder F4320327726 @default.
• W3137466538 hasFunder F4320333688 @default.
• W3137466538 hasIssue "3" @default.
• W3137466538 hasLocation W31374665381 @default.
• W3137466538 hasLocation W31374665382 @default.
• W3137466538 hasLocation W31374665383 @default.
• W3137466538 hasOpenAccess W3137466538 @default.
• W3137466538 hasPrimaryLocation W31374665381 @default.
• W3137466538 hasRelatedWork W2051712573 @default.

• next