FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137628472> ?p ?o ?g. }

• W3137628472 endingPage "1348" @default.
• W3137628472 startingPage "1348" @default.
• W3137628472 abstract "Background: The objective of our project was to identify a late recanalization predictor in ruptured intracranial aneurysms treated with coil embolization. This goal was achieved by means of a statistical analysis followed by a computational fluid dynamics (CFD) with porous media modelling approach. Porous media CFD simulated the hemodynamics within the aneurysmal dome after coiling. Methods: Firstly, a retrospective single center analysis of 66 aneurysmal subarachnoid hemorrhage patients was conducted. The authors assessed morphometric parameters, packing density, first coil volume packing density (1st VPD) and recanalization rate on digital subtraction angiograms (DSA). The effectiveness of initial endovascular treatment was visually determined using the modified Raymond–Roy classification directly after the embolization and in a 6- and 12-month follow-up DSA. In the next step, a comparison between porous media CFD analyses and our statistical results was performed. A geometry used during numerical simulations based on a patient-specific anatomy, where the aneurysm dome was modelled as a separate, porous domain. To evaluate hemodynamic changes, CFD was utilized for a control case (without any porosity) and for a wide range of porosities that resembled 1–30% of VPD. Numerical analyses were performed in Ansys CFX solver. Results: A multivariate analysis showed that 1st VPD affected the late recanalization rate (p < 0.001). Its value was significantly greater in all patients without recanalization (p < 0.001). Receiver operating characteristic curves governed by the univariate analysis showed that the model for late recanalization prediction based on 1st VPD (AUC 0.94 (95%CI: 0.86–1.00) is the most important predictor of late recanalization (p < 0.001). A cut-off point of 10.56% (sensitivity—0.722; specificity—0.979) was confirmed as optimal in a computational fluid dynamics analysis. The CFD results indicate that pressure at the aneurysm wall and residual flow volume (blood volume with mean fluid velocity > 0.01 m/s) within the aneurysmal dome tended to asymptotically decrease when VPD exceeded 10%. Conclusions: High 1st VPD decreases the late recanalization rate in ruptured intracranial aneurysms treated with coil embolization (according to our statistical results > 10.56%). We present an easy intraoperatively calculable predictor which has the potential to be used in clinical practice as a tip to improve clinical outcomes." @default.
• W3137628472 created "2021-03-29" @default.
• W3137628472 creator A5000581255 @default.
• W3137628472 creator A5002768441 @default.
• W3137628472 creator A5008275363 @default.
• W3137628472 creator A5010625763 @default.
• W3137628472 creator A5016826052 @default.
• W3137628472 creator A5020927385 @default.
• W3137628472 creator A5024575710 @default.
• W3137628472 creator A5087792867 @default.
• W3137628472 creator A5091653293 @default.
• W3137628472 date "2021-03-24" @default.
• W3137628472 modified "2023-09-29" @default.
• W3137628472 title "Porous Media Computational Fluid Dynamics and the Role of the First Coil in the Embolization of Ruptured Intracranial Aneurysms" @default.
• W3137628472 cites W1494398683 @default.
• W3137628472 cites W1558070983 @default.
• W3137628472 cites W1964175830 @default.
• W3137628472 cites W1972755818 @default.
• W3137628472 cites W1974636167 @default.
• W3137628472 cites W1975938924 @default.
• W3137628472 cites W1983709306 @default.
• W3137628472 cites W1989937958 @default.
• W3137628472 cites W1991385448 @default.
• W3137628472 cites W1992375374 @default.
• W3137628472 cites W2002306345 @default.
• W3137628472 cites W2031345969 @default.
• W3137628472 cites W2044375065 @default.
• W3137628472 cites W2050524363 @default.
• W3137628472 cites W2060851265 @default.
• W3137628472 cites W2064848924 @default.
• W3137628472 cites W2099951463 @default.
• W3137628472 cites W2101910302 @default.
• W3137628472 cites W2105995168 @default.
• W3137628472 cites W2107647647 @default.
• W3137628472 cites W2107655025 @default.
• W3137628472 cites W2109634262 @default.
• W3137628472 cites W2111268578 @default.
• W3137628472 cites W2132610783 @default.
• W3137628472 cites W2138123546 @default.
• W3137628472 cites W2147462813 @default.
• W3137628472 cites W2150825819 @default.
• W3137628472 cites W2155290115 @default.
• W3137628472 cites W2156778065 @default.
• W3137628472 cites W2157422321 @default.
• W3137628472 cites W2158557877 @default.
• W3137628472 cites W2161811333 @default.
• W3137628472 cites W2163275247 @default.
• W3137628472 cites W2163480988 @default.
• W3137628472 cites W2170555528 @default.
• W3137628472 cites W2224592020 @default.
• W3137628472 cites W2237239251 @default.
• W3137628472 cites W2260587245 @default.
• W3137628472 cites W2299053973 @default.
• W3137628472 cites W2580929028 @default.
• W3137628472 cites W2616555459 @default.
• W3137628472 cites W2776800305 @default.
• W3137628472 cites W2896218745 @default.
• W3137628472 cites W2959275913 @default.
• W3137628472 cites W2967387221 @default.
• W3137628472 cites W2971068829 @default.
• W3137628472 cites W3003149235 @default.
• W3137628472 cites W3012794911 @default.
• W3137628472 cites W3034372972 @default.
• W3137628472 doi "https://doi.org/10.3390/jcm10071348" @default.
• W3137628472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8037793" @default.
• W3137628472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33805169" @default.
• W3137628472 hasPublicationYear "2021" @default.
• W3137628472 type Work @default.
• W3137628472 sameAs 3137628472 @default.
• W3137628472 citedByCount "6" @default.
• W3137628472 countsByYear W31376284722022 @default.
• W3137628472 countsByYear W31376284722023 @default.
• W3137628472 crossrefType "journal-article" @default.
• W3137628472 hasAuthorship W3137628472A5000581255 @default.
• W3137628472 hasAuthorship W3137628472A5002768441 @default.
• W3137628472 hasAuthorship W3137628472A5008275363 @default.
• W3137628472 hasAuthorship W3137628472A5010625763 @default.
• W3137628472 hasAuthorship W3137628472A5016826052 @default.
• W3137628472 hasAuthorship W3137628472A5020927385 @default.
• W3137628472 hasAuthorship W3137628472A5024575710 @default.
• W3137628472 hasAuthorship W3137628472A5087792867 @default.
• W3137628472 hasAuthorship W3137628472A5091653293 @default.
• W3137628472 hasBestOaLocation W31376284721 @default.
• W3137628472 hasConcept C121332964 @default.
• W3137628472 hasConcept C126322002 @default.
• W3137628472 hasConcept C126838900 @default.
• W3137628472 hasConcept C141071460 @default.
• W3137628472 hasConcept C144301174 @default.
• W3137628472 hasConcept C1633027 @default.
• W3137628472 hasConcept C2776035437 @default.
• W3137628472 hasConcept C2776098176 @default.
• W3137628472 hasConcept C2777736543 @default.
• W3137628472 hasConcept C2778286760 @default.
• W3137628472 hasConcept C2780643987 @default.
• W3137628472 hasConcept C38180746 @default.
• W3137628472 hasConcept C57879066 @default.
• W3137628472 hasConcept C71924100 @default.
• W3137628472 hasConceptScore W3137628472C121332964 @default.

• next