FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137656339> ?p ?o ?g. }

• W3137656339 endingPage "129785" @default.
• W3137656339 startingPage "129785" @default.
• W3137656339 abstract "Differential chemosensors have emerged as next-generation systems due to their simplicity and favourable responsive properties to produce different signals upon selective binding of various analytes simultaneously. Nevertheless, given their inadequate fluorescence response and laborious synthetic procedures, only a few differential chemosensors have been developed so far. In this work, we have employed a single pot synthesis strategy to establish a new benzimidazole-based Schiff base type fluorogenic chemosensor (DFB) which differentially detects Cu2+ (detection limit (LOD) = 24.4 ± 0.5 nM) and Zn2+ (LOD = 2.18 ± 0.1 nM) through fluorescence “off-on” manner over the library of other metal cations in an aqueous medium. The DFB-derived ‘in situ’ complexes DFB-Cu2+ and DFB-Zn2+ showed fluorescence revival “on-off” responses toward cyanide (CN−) and bio-relevant pyrophosphate (P2O74--PPi) ions with a significantly low LOD of 9.43 ± 0.2 and 2.9 ± 0.1 nM, respectively, in water. We have demonstrated the phosphate group-specific binding capability of DFB-Zn2+, by testing it with both ssDNA and dsDNA samples which displayed fluorescence “turn-off” response (LOD ∼10-7 M), similar to the PPi binding in an aqueous medium, indicating that it interacts explicitly with the phosphate backbone of DNA. We have also harnessed the DFB as a sequential fluorescent probe to detect Cu2+, Zn2+, CN− and P2O74- ions in human cervical (HeLa) and breast (MCF-7 and MDA-MB-231 (aggressive and invasive)) cancer cell lines. Moreover, we have explored the PPi recognition capability of DFB-Zn2+ in the polymerase-chain-reaction (PCR) products where PPi is one of the primary by-products during amplification of DNA." @default.
• W3137656339 created "2021-03-29" @default.
• W3137656339 creator A5008389238 @default.
• W3137656339 creator A5033845318 @default.
• W3137656339 creator A5037943804 @default.
• W3137656339 creator A5063013653 @default.
• W3137656339 creator A5077968687 @default.
• W3137656339 date "2021-06-01" @default.
• W3137656339 modified "2023-10-03" @default.
• W3137656339 title "A benzimidazole-based new fluorogenic differential/sequential chemosensor for Cu2+, Zn2+, CN-, P2O74-, DNA, its live-cell imaging and pyrosequencing applications" @default.
• W3137656339 cites W1837731385 @default.
• W3137656339 cites W1845196127 @default.
• W3137656339 cites W1887586221 @default.
• W3137656339 cites W1929689722 @default.
• W3137656339 cites W1964173367 @default.
• W3137656339 cites W1966501049 @default.
• W3137656339 cites W1968556300 @default.
• W3137656339 cites W1972001693 @default.
• W3137656339 cites W1976181408 @default.
• W3137656339 cites W1977214047 @default.
• W3137656339 cites W1978612094 @default.
• W3137656339 cites W1978914643 @default.
• W3137656339 cites W1987565198 @default.
• W3137656339 cites W1988501179 @default.
• W3137656339 cites W1992742007 @default.
• W3137656339 cites W1994057432 @default.
• W3137656339 cites W1994815244 @default.
• W3137656339 cites W2001946936 @default.
• W3137656339 cites W2002215442 @default.
• W3137656339 cites W2005065130 @default.
• W3137656339 cites W2006256659 @default.
• W3137656339 cites W2007468675 @default.
• W3137656339 cites W2007969411 @default.
• W3137656339 cites W2012268127 @default.
• W3137656339 cites W2013032342 @default.
• W3137656339 cites W2015199191 @default.
• W3137656339 cites W2016305315 @default.
• W3137656339 cites W2020554458 @default.
• W3137656339 cites W2031934234 @default.
• W3137656339 cites W2033869458 @default.
• W3137656339 cites W2035212880 @default.
• W3137656339 cites W2035666802 @default.
• W3137656339 cites W2035880078 @default.
• W3137656339 cites W2038228027 @default.
• W3137656339 cites W2049286121 @default.
• W3137656339 cites W2050896043 @default.
• W3137656339 cites W2051242106 @default.
• W3137656339 cites W2052682096 @default.
• W3137656339 cites W2057666290 @default.
• W3137656339 cites W2060801384 @default.
• W3137656339 cites W2062724689 @default.
• W3137656339 cites W2074729393 @default.
• W3137656339 cites W2075463525 @default.
• W3137656339 cites W2076674332 @default.
• W3137656339 cites W2078107038 @default.
• W3137656339 cites W2092719748 @default.
• W3137656339 cites W2102496731 @default.
• W3137656339 cites W2106794687 @default.
• W3137656339 cites W2108926866 @default.
• W3137656339 cites W2122277786 @default.
• W3137656339 cites W2124297768 @default.
• W3137656339 cites W2150067511 @default.
• W3137656339 cites W2153630542 @default.
• W3137656339 cites W2154965937 @default.
• W3137656339 cites W2160313703 @default.
• W3137656339 cites W2167573033 @default.
• W3137656339 cites W2167978304 @default.
• W3137656339 cites W2170964653 @default.
• W3137656339 cites W2278726896 @default.
• W3137656339 cites W2294939273 @default.
• W3137656339 cites W2313035794 @default.
• W3137656339 cites W2313443708 @default.
• W3137656339 cites W2314606111 @default.
• W3137656339 cites W2316846621 @default.
• W3137656339 cites W2322069218 @default.
• W3137656339 cites W2323292362 @default.
• W3137656339 cites W2323991209 @default.
• W3137656339 cites W2332521488 @default.
• W3137656339 cites W2396578808 @default.
• W3137656339 cites W2405748615 @default.
• W3137656339 cites W2413593035 @default.
• W3137656339 cites W2528833138 @default.
• W3137656339 cites W2545409416 @default.
• W3137656339 cites W2547890841 @default.
• W3137656339 cites W2558698653 @default.
• W3137656339 cites W2561001816 @default.
• W3137656339 cites W2623338355 @default.
• W3137656339 cites W2748715071 @default.
• W3137656339 cites W2763434265 @default.
• W3137656339 cites W2783920331 @default.
• W3137656339 cites W2787195471 @default.
• W3137656339 cites W2804695782 @default.
• W3137656339 cites W2807578205 @default.
• W3137656339 cites W2895889294 @default.
• W3137656339 cites W2897503237 @default.
• W3137656339 cites W2908657525 @default.
• W3137656339 cites W2914525264 @default.
• W3137656339 cites W2925840180 @default.

• next