FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137664552> ?p ?o ?g. }

• W3137664552 endingPage "653" @default.
• W3137664552 startingPage "645" @default.
• W3137664552 abstract "The 12-lead electrocardiogram (ECG) is routinely performed in children with hypertrophic cardiomyopathy (HCM). An ECG risk score has been suggested as a useful tool for risk stratification, but this has not been independently validated. This aim of this study was to describe the ECG phenotype of childhood HCM in a large, international, multi-centre cohort and investigate its role in risk prediction for arrhythmic events.Data from 356 childhood HCM patients with a mean age of 10.1 years (±4.5) were collected from a retrospective, multi-centre international cohort. Three hundred and forty-seven (97.5%) patients had ECG abnormalities at baseline, most commonly repolarization abnormalities (n = 277, 77.8%); left ventricular hypertrophy (n = 240, 67.7%); abnormal QRS axis (n = 126, 35.4%); or QT prolongation (n = 131, 36.8%). Over a median follow-up of 3.9 years (interquartile range 2.0-7.7), 25 (7%) had an arrhythmic event, with an overall annual event rate of 1.38 (95% CI 0.93-2.04). No ECG variables were associated with 5-year arrhythmic event on univariable or multivariable analysis. The ECG risk score threshold of >5 had modest discriminatory ability [C-index 0.60 (95% CI 0.484-0.715)], with corresponding negative and positive predictive values of 96.7% and 6.7.In a large, international, multi-centre cohort of childhood HCM, ECG abnormalities were common and varied. No ECG characteristic, either in isolation or combined in the previously described ECG risk score, was associated with 5-year sudden cardiac death risk. This suggests that the role of baseline ECG phenotype in improving risk stratification in childhood HCM is limited." @default.
• W3137664552 created "2021-03-29" @default.
• W3137664552 creator A5004819858 @default.
• W3137664552 creator A5005775971 @default.
• W3137664552 creator A5006211041 @default.
• W3137664552 creator A5006716563 @default.
• W3137664552 creator A5011239865 @default.
• W3137664552 creator A5012026969 @default.
• W3137664552 creator A5012359524 @default.
• W3137664552 creator A5013450480 @default.
• W3137664552 creator A5017663636 @default.
• W3137664552 creator A5019877201 @default.
• W3137664552 creator A5022810365 @default.
• W3137664552 creator A5023015846 @default.
• W3137664552 creator A5023563117 @default.
• W3137664552 creator A5027001574 @default.
• W3137664552 creator A5028548591 @default.
• W3137664552 creator A5029153489 @default.
• W3137664552 creator A5031119081 @default.
• W3137664552 creator A5033829263 @default.
• W3137664552 creator A5034884428 @default.
• W3137664552 creator A5039143060 @default.
• W3137664552 creator A5043014481 @default.
• W3137664552 creator A5043583718 @default.
• W3137664552 creator A5043720811 @default.
• W3137664552 creator A5048123150 @default.
• W3137664552 creator A5054299469 @default.
• W3137664552 creator A5054455613 @default.
• W3137664552 creator A5056328033 @default.
• W3137664552 creator A5057095415 @default.
• W3137664552 creator A5059365360 @default.
• W3137664552 creator A5061023709 @default.
• W3137664552 creator A5062155971 @default.
• W3137664552 creator A5062980410 @default.
• W3137664552 creator A5063501784 @default.
• W3137664552 creator A5066512411 @default.
• W3137664552 creator A5068118299 @default.
• W3137664552 creator A5068918618 @default.
• W3137664552 creator A5070325308 @default.
• W3137664552 creator A5072386441 @default.
• W3137664552 creator A5074221016 @default.
• W3137664552 creator A5078231013 @default.
• W3137664552 creator A5081236967 @default.
• W3137664552 creator A5082650963 @default.
• W3137664552 creator A5083438870 @default.
• W3137664552 creator A5083610318 @default.
• W3137664552 creator A5083664150 @default.
• W3137664552 creator A5084319177 @default.
• W3137664552 creator A5085119245 @default.
• W3137664552 creator A5085386690 @default.
• W3137664552 creator A5086105005 @default.
• W3137664552 creator A5087200583 @default.
• W3137664552 creator A5091707158 @default.
• W3137664552 date "2021-03-27" @default.
• W3137664552 modified "2023-10-17" @default.
• W3137664552 title "The role of the electrocardiographic phenotype in risk stratification for sudden cardiac death in childhood hypertrophic cardiomyopathy" @default.
• W3137664552 cites W1996043685 @default.
• W3137664552 cites W2006444904 @default.
• W3137664552 cites W2020490598 @default.
• W3137664552 cites W2040622988 @default.
• W3137664552 cites W2045837103 @default.
• W3137664552 cites W2065877266 @default.
• W3137664552 cites W2087302565 @default.
• W3137664552 cites W2096508288 @default.
• W3137664552 cites W2097618980 @default.
• W3137664552 cites W2106024736 @default.
• W3137664552 cites W2119231255 @default.
• W3137664552 cites W2124178623 @default.
• W3137664552 cites W2126804529 @default.
• W3137664552 cites W2134843796 @default.
• W3137664552 cites W2153067557 @default.
• W3137664552 cites W2160232053 @default.
• W3137664552 cites W2212801488 @default.
• W3137664552 cites W2350064866 @default.
• W3137664552 cites W2470285974 @default.
• W3137664552 cites W2510819727 @default.
• W3137664552 cites W2590105723 @default.
• W3137664552 cites W2767154412 @default.
• W3137664552 cites W2768634522 @default.
• W3137664552 cites W2771167593 @default.
• W3137664552 cites W2789374978 @default.
• W3137664552 cites W2792696478 @default.
• W3137664552 cites W2792969537 @default.
• W3137664552 cites W2968371705 @default.
• W3137664552 cites W3004208181 @default.
• W3137664552 cites W3024147252 @default.
• W3137664552 cites W3045082596 @default.
• W3137664552 cites W4255063816 @default.
• W3137664552 doi "https://doi.org/10.1093/eurjpc/zwab046" @default.
• W3137664552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33772274" @default.
• W3137664552 hasPublicationYear "2021" @default.
• W3137664552 type Work @default.
• W3137664552 sameAs 3137664552 @default.
• W3137664552 citedByCount "15" @default.
• W3137664552 countsByYear W31376645522021 @default.
• W3137664552 countsByYear W31376645522022 @default.
• W3137664552 countsByYear W31376645522023 @default.
• W3137664552 crossrefType "journal-article" @default.

• next