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- W3137692419 abstract "Dear Editor, We would like to underline the role of reflectance confocal microscopy (RCM) in SSc skin involvement diagnosis. SSc, also defined as scleroderma as an immune-mediated rheumatic disease characterized by mild to plentiful skin fibrosis, is often related to massive involvement of internal organs, endothelial damage and skin localization [1]. Several studies published on SSc aetiology have allowed better assessment and disease management. The burden of non-lethal complications such as Raynaud’s phenomenon, musculoskeletal syndromes and fatigue associated with SSc is substantial, and likely to become more of a challenge [2]. Skin involvement, such as Raynaud’s phenomenon and digital ulcers, produces functional discomfort in everyday life, increasing disability and reducing quality of life [2, 3]. Nailfold video-capillaroscopy (NFC) is a simple, cheap, non-invasive and cost-effective technique to assess several morphological features of microvessels, such as architecture, shape, distribution, diameter and density; it..." @default.
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- W3137692419 date "2021-03-23" @default.
- W3137692419 modified "2023-09-30" @default.
- W3137692419 title "How reflectance confocal microscopy can be used in systemic sclerosis skin diagnosis" @default.
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- W3137692419 doi "https://doi.org/10.1093/rheumatology/keab241" @default.
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