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• W3137812447 abstract "Relatively little is known about outcomes of procedural sedation in very young children. Our objective was to examine the association between procedural sedation in young children (≤ 2 years) and the incidence of sedation-related adverse events. This is a secondary analysis of a prospective cohort study of children 0 to 18 years undergoing parenteral procedural sedation in six Canadian pediatric emergency departments (ED). The primary risk factor was age ≤ 2 years. Secondary risk factors were sex, procedure type, pre-procedure and sedation medications. The outcomes examined were: serious adverse events (SAE), significant interventions, oxygen desaturation and vomiting. Of the 6295 patients included, 946 (15%) were ≤2 years. Children 13–24 months comprised 90% of the young age group. Children ≤ 2 years were sedated most commonly for laceration repair (n = 450; 47.6%), while orthopedic reduction was most common in children > 2 (n = 3983; 74.5%). Ketamine was the most common medication in both groups, but was used more frequently in children ≤ 2 years (80.9% vs 58.9%; p < 0.001). There was no difference in the odds of SAE (OR 0.83, 95% Confidence Interval (CI) 0.4 to 1.9), significant intervention (OR 0.82, 95% CI 0.4 to 1.7) or oxygen desaturation (OR 0.95, 95% CI 0.7 to 1.3) between age groups, however children ≤ 2 years vomited less frequently (OR 0.24, 95% CI 0.1 to 0.6). Young age, specifically between 13 and 24 months, was not associated with a significant difference in the incidence of adverse events." @default.
• W3137812447 created "2021-03-29" @default.
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• W3137812447 date "2021-08-01" @default.
• W3137812447 modified "2023-09-27" @default.
• W3137812447 title "Impact of young age on outcomes of emergency department procedural sedation" @default.
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• W3137812447 doi "https://doi.org/10.1016/j.ajem.2021.03.014" @default.
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