Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137825520> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3137825520 endingPage "17" @default.
- W3137825520 startingPage "11" @default.
- W3137825520 abstract "Background: Our objective is to prospectively evaluate pixelated carbon dioxide (CO 2 ) laser therapy for the treatment of symptomatic genitourinary syndrome of menopause (GSM) over 1 year using both subjective and objective assessment methods. Methods: Subjects with symptomatic GSM completed pre-treatment evaluations. Subjects underwent three standardized pixelated CO 2 laser treatments 4 weeks apart. Use of other treatments during the study period was prohibited. Subjects completed five subjective GSM questionnaires (visual analog grading scale for vaginal atrophy symptoms (VAS-VA), Symptoms of Atrophic Vaginitis Questionnaire (SAVQ), and a modified Vulvovaginal Symptom Questionnaire (mVSQ), Urinary Distress Inventory (UDI-6) and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire (PISQ-12)) and physical assessments (Bachmann Vaginal Health Index (BVHI) and Vaginal Health Assessment (VHA)) 2 weeks after each treatment, and at 1 year. Vaginal cytologic maturation assessment was performed before and after each treatment. Three random subjects also underwent vaginal biopsy after treatments were completed. A P value of less than 0.05 was considered statistically significant. Results: Fifteen subjects were recruited with an average age of 58.3 years (range 43 - 70). Subjects had significant improvements on four of the five subjective assessments of GSM and on the two objective indices, from baseline to shortly after the third treatment, and were maintained at 1-year follow-up, with no worsening of the improvements. Subjects did not have significant improvement in urinary symptoms. Histologically, the surface epithelium ranged from within normal limits to mild squamous atrophy. There was mild submucosal vascular congestion in all specimens, with evident neovascularization. Conclusions: Clinically significant improvement was noted in subjective and objective assessments of GSM, and was sustained for 1 year following pixelated CO 2 laser therapy. Histologic changes were consistent with mild submucosal neovascularization rather than estrogen-like epithelial squamous maturation. J Clin Gynecol Obstet. 2021;10(1):11-17 doi: https://doi.org/10.14740/jcgo729" @default.
- W3137825520 created "2021-03-29" @default.
- W3137825520 creator A5000666887 @default.
- W3137825520 creator A5021309563 @default.
- W3137825520 creator A5035779084 @default.
- W3137825520 creator A5046005517 @default.
- W3137825520 creator A5053544853 @default.
- W3137825520 date "2021-03-17" @default.
- W3137825520 modified "2023-10-07" @default.
- W3137825520 title "Prospective Study of Fractional Carbon Dioxide Laser Therapy for Symptoms of Genitourinary Syndrome of Menopause: One-Year Follow-Up" @default.
- W3137825520 doi "https://doi.org/10.14740/jcgo.v10i1.729" @default.
- W3137825520 hasPublicationYear "2021" @default.
- W3137825520 type Work @default.
- W3137825520 sameAs 3137825520 @default.
- W3137825520 citedByCount "0" @default.
- W3137825520 crossrefType "journal-article" @default.
- W3137825520 hasAuthorship W3137825520A5000666887 @default.
- W3137825520 hasAuthorship W3137825520A5021309563 @default.
- W3137825520 hasAuthorship W3137825520A5035779084 @default.
- W3137825520 hasAuthorship W3137825520A5046005517 @default.
- W3137825520 hasAuthorship W3137825520A5053544853 @default.
- W3137825520 hasConcept C126322002 @default.
- W3137825520 hasConcept C133507102 @default.
- W3137825520 hasConcept C141071460 @default.
- W3137825520 hasConcept C14184104 @default.
- W3137825520 hasConcept C2777333188 @default.
- W3137825520 hasConcept C2778531004 @default.
- W3137825520 hasConcept C2778562196 @default.
- W3137825520 hasConcept C29456083 @default.
- W3137825520 hasConcept C71924100 @default.
- W3137825520 hasConcept C77411442 @default.
- W3137825520 hasConceptScore W3137825520C126322002 @default.
- W3137825520 hasConceptScore W3137825520C133507102 @default.
- W3137825520 hasConceptScore W3137825520C141071460 @default.
- W3137825520 hasConceptScore W3137825520C14184104 @default.
- W3137825520 hasConceptScore W3137825520C2777333188 @default.
- W3137825520 hasConceptScore W3137825520C2778531004 @default.
- W3137825520 hasConceptScore W3137825520C2778562196 @default.
- W3137825520 hasConceptScore W3137825520C29456083 @default.
- W3137825520 hasConceptScore W3137825520C71924100 @default.
- W3137825520 hasConceptScore W3137825520C77411442 @default.
- W3137825520 hasIssue "1" @default.
- W3137825520 hasLocation W31378255201 @default.
- W3137825520 hasOpenAccess W3137825520 @default.
- W3137825520 hasPrimaryLocation W31378255201 @default.
- W3137825520 hasRelatedWork W2070396328 @default.
- W3137825520 hasRelatedWork W2129403191 @default.
- W3137825520 hasRelatedWork W2327044515 @default.
- W3137825520 hasRelatedWork W2398704040 @default.
- W3137825520 hasRelatedWork W2600904352 @default.
- W3137825520 hasRelatedWork W2615205819 @default.
- W3137825520 hasRelatedWork W2790551925 @default.
- W3137825520 hasRelatedWork W2807080769 @default.
- W3137825520 hasRelatedWork W2953954225 @default.
- W3137825520 hasRelatedWork W2954200390 @default.
- W3137825520 hasRelatedWork W2964650992 @default.
- W3137825520 hasRelatedWork W2981271458 @default.
- W3137825520 hasRelatedWork W2992070041 @default.
- W3137825520 hasRelatedWork W3020636412 @default.
- W3137825520 hasRelatedWork W3110124809 @default.
- W3137825520 hasRelatedWork W3120196669 @default.
- W3137825520 hasRelatedWork W3122089129 @default.
- W3137825520 hasRelatedWork W3131585854 @default.
- W3137825520 hasRelatedWork W3154561796 @default.
- W3137825520 hasRelatedWork W3201811455 @default.
- W3137825520 hasVolume "10" @default.
- W3137825520 isParatext "false" @default.
- W3137825520 isRetracted "false" @default.
- W3137825520 magId "3137825520" @default.
- W3137825520 workType "article" @default.